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Protein Page:
PDE4DIP (human)

PDE4DIP May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes. A chromosomal aberration involving PDE4DIP may be the cause of a myeloproliferative disorder (MBD) associated with eosinophilia. Translocation t(1;5)(q23;q33) that forms a PDE4DIP- PDGFRB fusion protein. 11 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 1q12
Cellular Component: centrosome; cytoplasm; Golgi apparatus; myofibril; nucleus
Molecular Function: enzyme binding; protein binding
Biological Process: cellular protein complex assembly
Reference #:  Q5VU43-2 (UniProtKB)
Alt. Names/Synonyms: cardiomyopathy associated 2; Cardiomyopathy-associated protein 2; CMYA2; DKFZp781J054; KIAA0454; KIAA0477; MGC75440; MMGL; MYOME; Myomegalin; PDE4DIP; phosphodiesterase 4D interacting protein; Phosphodiesterase 4D-interacting protein
Gene Symbols: PDE4DIP
Molecular weight: 128,464 Da
Basal Isoelectric point: 5.04  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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