delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass
Cellular Component: integral to plasma membrane; intrinsic to plasma membrane; neuron projection; plasma membrane
Molecular Function: neuropeptide binding; opioid receptor activity; protein binding
Biological Process: activation of CREB transcription factor; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; negative regulation of protein oligomerization; neuropeptide signaling pathway; positive regulation of peptidyl-serine phosphorylation; protein import into nucleus, translocation; regulation of mitochondrial membrane potential; sensory perception of pain; synaptic transmission
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.