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Protein Page:
PLCB2 (human)

Overview
PLCB2 The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - inositol phosphate; EC 3.1.4.11; Phospholipase
Chromosomal Location of Human Ortholog: 15q15
Cellular Component: cytosol
Molecular Function: phosphoinositide phospholipase C activity; phospholipase C activity
Biological Process: inositol phosphate metabolic process; phospholipase C activation; phospholipid metabolic process; Wnt receptor signaling pathway, calcium modulating pathway
Reference #:  Q00722 (UniProtKB)
Alt. Names/Synonyms: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; FLJ38135; Phosphoinositide phospholipase C-beta-2; phospholipase C, beta 2; Phospholipase C-beta-2; PLC-beta-2; PLCB2
Gene Symbols: PLCB2
Molecular weight: 134,024 Da
Basal Isoelectric point: 5.96  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics  |  AMPK Signaling  |  ErbB/HER Signaling  |  GPCR Signaling to MAPKs
Select Structure to View Below

PLCB2

Protein Structure Not Found.
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