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Protein Page:
CYP1A1 (human)

CYP1A1 Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - tryptophan; Cofactor and Vitamin Metabolism - retinol; EC; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 15q24.1
Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle
Molecular Function: monooxygenase activity; oxidoreductase activity; oxygen binding; protein binding
Biological Process: drug metabolic process; epoxygenase P450 pathway; ethylene metabolic process; vitamin D metabolic process
Reference #:  P04798 (UniProtKB)
Alt. Names/Synonyms: AHH; AHRR; aryl hydrocarbon hydroxylase; CP11; CP1A1; CYP1; CYP1A1; CYPIA1; cytochrome P1-450, dioxin-inducible; Cytochrome P450 1A1; Cytochrome P450 form 6; cytochrome P450, family 1, subfamily A, polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; Cytochrome P450-C; Cytochrome P450-P1; flavoprotein-linked monooxygenase; P1-450; P450-C; P450DX
Gene Symbols: CYP1A1
Molecular weight: 58,165 Da
Basal Isoelectric point: 8.61  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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