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Protein Page:
PANX1 (human)

PANX1 Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Belongs to the pannexin family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 11q21
Cellular Component: endoplasmic reticulum; membrane; plasma membrane
Molecular Function: calcium channel activity; gap junction hemi-channel activity; leak channel activity; receptor binding
Biological Process: calcium ion transport; cation transport; cell-cell signaling; positive regulation of interleukin-1 beta secretion
Reference #:  Q96RD7 (UniProtKB)
Alt. Names/Synonyms: innexin; MGC21309; MRS1; pannexin 1; Pannexin-1; PANX1; PX1; UNQ2529
Gene Symbols: PANX1
Molecular weight: 48,050 Da
Basal Isoelectric point: 5.75  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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