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Protein Page:
Myb (mouse)

Myb Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. 6 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Cellular Component: cytosol; nucleus
Molecular Function: DNA binding; protein binding; transcription factor activity
Biological Process: B cell differentiation; calcium ion transport; chromatin remodeling; embryonic gut development; G1/S transition of mitotic cell cycle; homeostasis of number of cells; in utero embryonic development; myeloid cell differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of histone H3-K4 methylation; positive regulation of histone H3-K9 methylation; positive regulation of T-helper cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of gene expression; regulation of transcription, DNA-dependent; spleen development; stem cell division; thymus development
Reference #:  P06876 (UniProtKB)
Alt. Names/Synonyms: AI550390; c-myb; gag-myb protein; M16449; MGC18531; Myb; myb proto-oncogene protein; myeloblastosis oncogene; myeloblastosis proto-oncogene product; Proto-oncogene c-Myb; Transcriptional activator Myb; tumor-specific myb protein
Gene Symbols: Myb
Molecular weight: 71,422 Da
Basal Isoelectric point: 6.45  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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