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Protein Page:
NCDN (human)

NCDN Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin- concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth. Belongs to the neurochondrin family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Inhibitor
Chromosomal Location of Human Ortholog: 1p34.3
Cellular Component: axon; cell soma; cytosol; dendrite; membrane; nucleus
Molecular Function: protein binding
Biological Process: neurite development
Reference #:  Q9UBB6 (UniProtKB)
Alt. Names/Synonyms: KIAA0607; NCDN; Neurochondrin
Gene Symbols: NCDN
Molecular weight: 78,864 Da
Basal Isoelectric point: 5.34  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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