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Protein Page:
KCTD7 (human)

Overview
KCTD7 contains a K+ channel tetramerisation domain (T1) found in voltage-gated K+ channel proteins. Encodes molecular determinants for the assembly of functional tetrameric channels. Two alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 7q11.21
Cellular Component: cytosol; plasma membrane
Biological Process: protein homooligomerization
Disease: Epilepsy, Progressive Myoclonic 3, With Or Without Intracellular Inclusions
Reference #:  Q96MP8 (UniProtKB)
Alt. Names/Synonyms: BTB/POZ domain-containing protein KCTD7; EPM3; FLJ32069; KCTD7; potassium channel tetramerisation domain containing 7
Gene Symbols: KCTD7
Molecular weight: 33,132 Da
Basal Isoelectric point: 5.58  Predict pI for various phosphorylation states
Select Structure to View Below

KCTD7

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 10 Y131‑p AVYKEAQyYAIGPLL
0 1 Y162‑p AFLGLMPyyKDHLER
0 1 Y163‑p FLGLMPyyKDHLERI
0 6 T200‑p FKEEMPItPYECPLL
0 1 Y202 EEMPItPYECPLLNS
0 1 S209 YECPLLNSLRFERSE
  mouse

 
Y131 AVHKEAQYYAIGPLL
Y162 AFLGLMPYYKDHLER
Y163 FLGLMPYYKDHLERI
T200‑p FKEEMPItPYECPLL
Y202 EEMPItPYECPLLNS
S209 YECPLLNSLRFERSE
  rat

 
Y297 AVHKEAQYYAIGPLL
Y328 AFLGLMPYYKDHLER
Y329 FLGLMPYYKDHLERI
T366 FKEEMPITPyECPLL
Y368‑p EEMPITPyECPLLNs
S375‑p yECPLLNsLRFERSE
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