Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
GABRR3 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
GABRR3 GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR3 sub-subfamily. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel; Channel, ligand-gated
Chromosomal Location of Human Ortholog: 3q11.2
Cellular Component: plasma membrane
Molecular Function: GABA-A receptor activity
Reference #:  A8MPY1 (UniProtKB)
Alt. Names/Synonyms: DKFZp781O1955; GABA(A) receptor subunit rho-3; GABRR3; gamma-aminobutyric acid (GABA) receptor, rho 3; Gamma-aminobutyric acid receptor subunit rho-3; GBRR3
Gene Symbols: GABRR3
Molecular weight: 54,272 Da
Basal Isoelectric point: 8.33  Predict pI for various phosphorylation states
Select Structure to View Below

GABRR3

Protein Structure Not Found.


STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment



 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K49‑ac CKQETRMkKDDSTkA
0 2 K55‑ac MkKDDSTkARPQkYE
0 1 K60‑ac STkARPQkYEQLLHI
0 1 S175‑p PDGNVLLsLRITVSA
0 1 S427‑p SRIKRRKsLGGHVGR
  mouse

 
R46 RIRETRMRKDDLTKV
K52 MRKDDLTKVWHPKRE
K57 LTKVWHPKREQLLHI
S172 PDGNVLFSLRITVSA
S424 SSQIKRKSLGGNVGR
  rat

 
R46 RIRETRMRKDDLTKV
K52 MRKDDLTKVWPLKRE
K57 LTKVWPLKREQLLHI
S172 PDGNVLFSLRITVSA
S424 SSQIKRKSLGGNVGR
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.