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Protein Page:
Oct11 (human)

Overview
Oct11 Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a number of genes such as SPRR2A or placental lactogen. Belongs to the POU transcription factor family. Class- 2 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: cytoplasm; nucleoplasm; nucleus; transcription factor complex
Molecular Function: protein binding; protein dimerization activity; sequence-specific DNA binding
Biological Process: epidermis development; keratinocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; wound healing
Reference #:  Q9UKI9 (UniProtKB)
Alt. Names/Synonyms: Epoc-1; FLJ40063; MGC126698; Oct-11; OCT11; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF-11; OTF11; PLA-1; PLA1; PO2F3; POU class 2 homeobox 3; POU domain, class 2, transcription factor 3; POU transcription factor; POU2F3; Skn-1a; Transcription factor PLA-1; Transcription factor Skn-1
Gene Symbols: POU2F3
Molecular weight: 47,432 Da
Basal Isoelectric point: 8.66  Predict pI for various phosphorylation states
Select Structure to View Below

Oct11

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 S14‑p MHTDIKMsGDVADst
0 1 S20‑p MsGDVADstDARSTL
0 1 T21‑p sGDVADstDARSTLS
0 11 S238‑p RFEALNLsFKNMCKL
0 1 S258‑p KWLNDAEssPSDPSV
0 1 S259‑p WLNDAEssPSDPSVS
0 8 S287‑p RKRKKRTsIETNIRL
  Oct11 iso2  
S16 GGRDIKMSGDVADST
S22 MSGDVADSTDARSTL
T23 SGDVADSTDARSTLS
S240 RFEALNLSFKNMCKL
S260 KWLNDAESSPSDPSV
S261 WLNDAESSPSDPSVS
S289 RKRKKRTSIETNIRL
  mouse

 
S14 MHTEIKMSGDVADST
S20 MSGDVADSTDTRSTF
T21 SGDVADSTDTRSTFG
S231 RFEALNLSFKNMCKL
S251 KWLNDPESSPSDPSA
S252 WLNDPESSPSDPSAS
S280‑p RKRKKRTsIETNIRL
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