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Protein Page:
REM1 (human)

Overview
REM1 Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling. Belongs to the small GTPase superfamily. RGK family. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric, RGK; G protein, monomeric
Chromosomal Location of Human Ortholog: 20q11.21
Cellular Component: intracellular; membrane
Molecular Function: calmodulin binding; GTP binding
Biological Process: small GTPase mediated signal transduction
Reference #:  O75628 (UniProtKB)
Alt. Names/Synonyms: GD:REM; GES; GTP-binding protein REM 1; GTPase GES; GTPase-regulating endothelial cell sprouting; MGC48669; Rad and Gem-like GTP-binding protein 1; RAS (RAD and GEM)-like GTP-binding 1; REM; REM1
Gene Symbols: REM1
Molecular weight: 32,947 Da
Basal Isoelectric point: 9.02  Predict pI for various phosphorylation states
Select Structure to View Below

REM1

Protein Structure Not Found.


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Sites Implicated In
intracellular localization: S18‑p
molecular association, regulation: S18‑p

Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
1 8 S18‑p TPLHRRAsTPLPLSP
0 2 T19 PLHRRAsTPLPLSPR
0 2 S24 AsTPLPLSPRGHQPG
0 5 S51 PRLGQSASLNPPTQK
0 1 S168‑p YSIADRGsFEsASEL
0 1 S171‑p ADRGsFEsASELRIQ
0 1 S250‑p LRLRRRDsAAKEPPA
0 1 P255 RDsAAKEPPAPRRPA
0 1 A257 sAAKEPPAPRRPASL
1 0 S263 PAPRRPASLAQRARR
1 0 S289 RRALKARSKSCHNLA
0 3 S291 ALKARSKSCHNLAVL
  mouse

 
S18‑p TTLRRRAstPLPLsS
T19‑p TLRRRAstPLPLsSR
S24‑p AstPLPLsSRGHQPG
S51‑p PRLGQSVsLNPPVRK
S167 YSIADRSSFESASEL
S170 ADRSSFESASELRIQ
N249 LRLRRQDNAAPEtPs
T254‑p QDNAAPEtPsPRRRA
S256‑p NAAPEtPsPRRRAsL
S262‑p PsPRRRAsLGQRARR
S288‑p RRALKARsKsCHNLA
S290‑p ALKARsKsCHNLAVL
  rat

 
S18 TTLRRRASTPLPLSS
T19 TLRRRASTPLPLSSR
S24 ASTPLPLSSRGHQPG
S51‑p PRLGQSAsLNPPIRK
S167 YSIADRSSFESASEL
S170 ADRSSFESASELRIQ
N249 LRLRRQDNAAPETPS
T254 QDNAAPETPSPRRRA
S256 NAAPETPSPRRRASL
S262 PSPRRRASLGQRARR
S288 RRALKARSKSCHNLA
S290 ALKARSKSCHNLAVL
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