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Protein Page:
BKR2 (human)

Overview
BKR2 a receptor for bradykinin. Bradykinin elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 14q32.1-q32.2
Cellular Component: endosome; integral to plasma membrane; plasma membrane
Molecular Function: bradykinin receptor activity; phosphoinositide phospholipase C activity; protease binding; protein binding; protein heterodimerization activity; type 1 angiotensin receptor binding
Biological Process: arachidonic acid secretion; cell surface receptor linked signal transduction; elevation of cytosolic calcium ion concentration; inflammatory response; regulation of vascular permeability; regulation of vasoconstriction; smooth muscle contraction; transmembrane receptor protein tyrosine kinase signaling pathway
Reference #:  P30411 (UniProtKB)
Alt. Names/Synonyms: B2 bradykinin receptor; B2R; BDKRB2; BK-2; BK-2 receptor; BK2; BKR2; BKRB2; bradykinin receptor B2; BRB2; DKFZp686O088
Gene Symbols: BDKRB2
Molecular weight: 44,461 Da
Basal Isoelectric point: 8.5  Predict pI for various phosphorylation states
Select Structure to View Below

BKR2

Protein Structure Not Found.


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