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Protein Page:
GSC (human)

GSC Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring. Belongs to the paired homeobox family. Bicoid subfamily. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 14q32.1
Biological Process: middle ear morphogenesis; neural crest cell fate specification
Disease: Short Stature, Auditory Canal Atresia, Mandibular Hypoplasia, And Skeletal Abnormalities
Reference #:  P56915 (UniProtKB)
Alt. Names/Synonyms: goosecoid homeobox; GSC; Homeobox protein goosecoid
Gene Symbols: GSC
Molecular weight: 28,150 Da
Basal Isoelectric point: 8.86  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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