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Protein Page:
STAT4 (human)

STAT4 transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 2q32.2-q32.3
Cellular Component: nucleoplasm
Biological Process: JAK-STAT cascade
Disease: Systemic Lupus Erythematosus, Susceptibility To, 11
Reference #:  Q14765 (UniProtKB)
Alt. Names/Synonyms: Signal transducer and activator of transcription 4; SLEB11; STAT4
Gene Symbols: STAT4
Molecular weight: 85,941 Da
Basal Isoelectric point: 6.2  Predict pI for various phosphorylation states
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