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Protein Page:
SGCB (human)

SGCB Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCB are the cause of limb-girdle muscular dystrophy type 2E (LGMD2E). LGMD2E is an autosomal recessive disorder. Belongs to the sarcoglycan beta/delta/gamma/zeta family. Note: This description may include information from UniProtKB.
Protein type: Dystrophin complex; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q12
Cellular Component: dystrophin-associated glycoprotein complex; integral to plasma membrane
Disease: Muscular Dystrophy, Limb-girdle, Type 2e
Reference #:  Q16585 (UniProtKB)
Alt. Names/Synonyms: 43 kDa dystrophin-associated glycoprotein; 43DAG; A3b; Beta-sarcoglycan; beta-sarcoglycan(43kD dystrophin-associated glycoprotein); Beta-SG; LGMD2E; limb girdle muscular dystrophy 2E (non-linked families); sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); SGC; SGCB
Gene Symbols: SGCB
Molecular weight: 34,777 Da
Basal Isoelectric point: 8.86  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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