Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
HLAC (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
HLAC Involved in the presentation of foreign antigens to the immune system. Belongs to the MHC class I family. Note: This description may include information from UniProtKB.
Protein type: Receptor, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: Golgi membrane; Golgi apparatus; phagocytic vesicle membrane; cell surface; endoplasmic reticulum; early endosome membrane; integral to plasma membrane; plasma membrane; extracellular region; MHC class I protein complex
Molecular Function: peptide antigen binding; TAP binding; receptor binding
Biological Process: regulation of immune response; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of peptide antigen via MHC class I; viral reproduction; positive regulation of T cell mediated cytotoxicity; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; cytokine and chemokine mediated signaling pathway; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; immune response
Disease: Psoriasis 1, Susceptibility To; Human Immunodeficiency Virus Type 1, Susceptibility To
Reference #:  P30501 (UniProtKB)
Alt. Names/Synonyms: 1C02; class I MHC antigen HLA-B heavy chain; D6S204; FLJ27082; HLA class I antigen; HLA class I heavy chain; HLA class I histocompatibility antigen, C alpha chain; HLA class I histocompatibility antigen, Cw-1 alpha chain; HLA class I histocompatibility antigen, Cw-12 alpha chain; HLA class I histocompatibility antigen, Cw-14 alpha chain; HLA class I histocompatibility antigen, Cw-16 alpha chain; HLA class I histocompatibility antigen, Cw-17 alpha chain; HLA class I histocompatibility antigen, Cw-2 alpha chain; HLA class I histocompatibility antigen, Cw-4 alpha chain; HLA class I histocompatibility antigen, Cw-6 alpha chain; HLA class I histocompatibility antigen, Cw-7 alpha chain; HLA class I histocompatibility antigen, Cw-8 alpha chain; HLA-C; HLA-C (Cw*1201); HLA-Cw; HLA-Cw*050x; HLA-Cw12; HLA-JY3; HLAC; HLC-C; human leukocyte antigen-C alpha chain; leucocyte antigen C; leucocyte antigen Cw; leukocyte antigen-C alpha chain; major histocompatibility antigen HLA-C; major histocompatibility complex, class I, C; MHC class I antigen Cw*1; MHC class I antigen Cw*12; MHC class I antigen Cw*14; MHC class I antigen Cw*16; MHC class I antigen Cw*17; MHC class I antigen Cw*2; MHC class I antigen Cw*4; MHC class I antigen Cw*6; MHC class I antigen Cw*7; MHC class I antigen Cw*8; MHC class I antigen heavy chain HLA-C; MHC class I antigen HLA-C; MHC class I HLA-C; MHC class I HLA-Cw*0803; MHC class I protein HLA-C heavy chain; PSORS1
Gene Symbols: HLA-C
Molecular weight: 41,095 Da
Basal Isoelectric point: 5.76  Predict pI for various phosphorylation states
Select Structure to View Below

HLAC

Protein Structure Not Found.


STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 2 - gap
0 5 - gap
0 10 - gap
0 2 S350 GSCSQAASSNSAQGs
0 3 S351 SCSQAASSNSAQGsD
0 2 S353 SQAASSNSAQGsDES
0 1 T20 LSGALALTETWACSH
0 25 K200 RRYLENGKEKLQRAE
0 1 S28 ETWACSHSMRYFYTA
0 1 Y31 ACSHSMRYFYTAVSR
0 1 T55 AVGYVDDTQFVRFDS
0 1 Y83-p VEQEGPEyWDRETQk
0 1 K90-ub yWDRETQkYNRQAQT
0 1 N92 DRETQkYNRQAQTDR
0 1 T97 kYNRQAQTDRVNLRK
0 10 K145-ub DQSAYDGkDYIALNE
0 2 Y147 SAYDGkDYIALNEDL
0 1 S156 ALNEDLRSWTAADTA
0 1 T162 RSWTAADTAAQITQR
0 4 K170-ub AAQITQRkWEAAREA
0 1 Y183 EAEEWRAYLEGECVE
0 1 W191 LEGECVEWLRRYLEN
0 1 Y195 CVEWLRRYLENGKEK
0 8 K202 YLENGKEKLQRAEHP
0 5 K210-ub LQRAEHPkTHVTHHP
0 10 K267-ub AGDGTFQkWAAVVVP
0 1 A270 GTFQkWAAVVVPSGE
0 1 - gap
0 14 K341 RRKSSGGKGGSCSQA
0 41 - gap
0 9 - gap
0 24 S357-p SSNSAQGsDESLIAS
0 31 S360 SAQGsDESLIASKA_
0 47 K365 DESLIASKA______
  HLAC iso2  
- gap
- gap
- gap
S350 GSCSQAASSNSAQGS
S351 SCSQAASSNSAQGSD
S353 SQAASSNSAQGSDES
T20 LSGALALTETWACSH
K200 RRYLENGKESLQRAE
S28 ETWACSHSMKYFFTS
Y31 ACSHSMKYFFTSVSR
T55 SVGYVDDTQFVRFDS
Y83 VEQEGPEYWDRETQK
K90 YWDRETQKYNRQAQT
N92 DRETQKYNRQAQTDR
T97 KYNRQAQTDRVSLRN
K145-ub DQYAYDGkDYIALNE
Y147 YAYDGkDYIALNEDL
S156 ALNEDLRSWTAADTA
T162 RSWTAADTAAQITQR
K170 AAQITQRKWEAAREA
Y183 EAEERRAYLEGTCVE
W191 LEGTCVEWLRRYLEN
Y195 CVEWLRRYLENGKES
S202 YLENGKESLQRAEHP
K210 LQRAEHPKTHVTHHP
K267 AGDGTFQKWAAVMVP
A270 GTFQKWAAVMVPSGE
- gap
K341 RRKSSGGKGGSCSQA
- gap
- gap
S357 SSNSAQGSDESLIAS
S360 SAQGSDESLIASKA_
K365 DESLIASKA______
  HLAC iso5  
- gap
- gap
- gap
S350-p GSCSQAAssNsAQGs
S351-p SCSQAAssNsAQGsD
S353-p SQAAssNsAQGsDEs
T20 LSGALALTETWACSH
K200 RRYLENGKKTLQRAE
S28 ETWACSHSMRyFYTA
Y31-p ACSHSMRyFYTAVSR
T55 AVGYVDDTQFVQFDS
Y83 VEQEGPEYWDRETQK
K90 YWDRETQKYKRQAQT
K92 DRETQKYKRQAQTDR
T97 KYKRQAQTDRVNLRK
K145-ub NQFAYDGkDyIALNE
Y147-p FAYDGkDyIALNEDL
S156 ALNEDLRSWTAADkA
K162-ub RSWTAADkAAQITQR
K170 AAQITQRKWEAAREA
Y183 EAEQRRAYLEGTCVE
W191 LEGTCVEWLRRYLEN
Y195 CVEWLRRYLENGKKT
T202 YLENGKKTLQRAEHP
K210-ub LQRAEHPkTHVTHHP
K267-ub AGDGTFQkWAAVVVP
A270 GTFQkWAAVVVPSGE
- gap
K341-ub RRKSSGGkGGSCSQA
- gap
- gap
S357-p ssNsAQGsDEsLIAC
S360-p sAQGsDEsLIACkA_
K365-ub DEsLIACkA______
  HLAC iso7  
- gap
- gap
- gap
- gap
S351 SCSQAACSNSAQGsD
S353 SQAACSNSAQGsDEs
T20 LSGGLALTETWACSH
K200-ub RRyLENGkEtLQRAE
S28 ETWACSHSMRYFDTA
Y31 ACSHSMRYFDTAVSR
T55 SVGYVDDTQFVRFDS
Y83 VEQEGPEYWDRETQK
K90 YWDRETQKYKRQAQA
K92 DRETQKYKRQAQADR
A97 KYKRQAQADRVSLRN
K145 DQSAYDGKDYIALNE
Y147 SAYDGKDYIALNEDL
S156 ALNEDLRSWTAADTA
T162 RSWTAADTAAQITQR
K170 AAQITQRKLEAARAA
Y183-p AAEQLRAyLEGTCVE
W191 LEGTCVEWLRRyLEN
Y195-p CVEWLRRyLENGkEt
T202-p yLENGkEtLQRAEPP
K210 LQRAEPPKTHVTHHP
K267-ub AGDGTFQkWAAVVVP
A270 GTFQkWAAVVVPSGQ
- gap
K341-ub RRKSSGGkGGSCSQA
- gap
- gap
S357-p CSNSAQGsDEsLITC
S360-p SAQGsDEsLITCkA_
K365-ub DEsLITCkA______
  HLAC iso14  
T351-p RsGVWPAtVPRALMS
- gap
- gap
- gap
- gap
- gap
T20 LSGALALTETWACSH
K200 RRYLENGKKTLQRAE
S28 ETWACSHSMRyFYTA
Y31-p ACSHSMRyFYTAVSR
T55 AVGYVDDTQFVQFDS
Y83 VEQEGPEYWDRETQK
K90 YWDRETQKYKRQAQT
K92 DRETQKYKRQAQTDR
T97 KYKRQAQTDRVNLRK
K145 NQFAYDGKDYIALNE
Y147 FAYDGKDYIALNEDL
S156 ALNEDLRSWTAADKA
K162 RSWTAADKAAQITQR
K170 AAQITQRKWEAAREA
Y183 EAEQRRAYLEGTCVE
W191 LEGTCVEWLRRYLEN
Y195 CVEWLRRYLENGKKT
T202 YLENGKKTLQRAEHP
K210 LQRAEHPKTHVTHHP
K267 AGDGTFQKWAAVVVP
A270 GTFQKWAAVVVPSGE
S345-p SGREGVRsGVWPAtV
- gap
- gap
- gap
- gap
- gap
- gap
  HLAC iso15  
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S3 _____SHSMRyFYTA
Y6-p __SHSMRyFYTAVSR
T30 AVGYVDDTQFVRFDS
Y58 VEQEGPEYWDRETQN
N65 YWDRETQNYkRQAQT
K67-ub DRETQNYkRQAQTDR
T72 NYkRQAQTDRVNLRK
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- under review  
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
  HLAC iso20  
- gap
- gap
- gap
C350 GSCSQAACSNSAQGs
S351 SCSQAACSNSAQGsD
S353 SQAACSNSAQGsDEs
T20 LSGGLALTETWACSH
K200 RRYLENGKKTLQRAE
S28 ETWACSHSMRYFDTA
Y31 ACSHSMRYFDTAVSR
T55 SVGYVDDTQFVRFDS
Y83 VEQEGPEYWDRETQK
K90 YWDRETQKYKRQAQA
K92 DRETQKYKRQAQADR
A97 KYKRQAQADRVSLRN
K145-ub DQFAYDGkDYIALNE
Y147 FAYDGkDYIALNEDL
S156 ALNEDLRSWTAADTA
T162 RSWTAADTAAQITQR
K170 AAQITQRKLEAARAA
Y183 AAEQDRAYLEGTCVE
W191 LEGTCVEWLRRYLEN
Y195 CVEWLRRYLENGKKT
T202 YLENGKKTLQRAEPP
K210 LQRAEPPKTHVTHHP
K267-ub AGDGTFQkWAAVVVP
A270 GTFQkWAAVVVPSGQ
- gap
K341 RRKSSGGKGGSCSQA
- gap
- gap
S357-p CSNSAQGsDEsLITC
S360-p SAQGsDEsLITCkA_
K365-ub DEsLITCkA______
  mouse

► Hide Isoforms
 
- gap
- gap
S352 TLTPGSQSsEMsLPD
- gap
- gap
- gap
A20 LAAALAPAQTRAGPH
N200 RRYLELGNATLLHTD
S28 QTRAGPHSLRYFETV
Y31 AGPHSLRYFETVVSR
T55 SVGYVDNTEFVRFDS
Y83 MEQEGPEYWERETQI
I90 YWERETQIAKGNEQS
K92 ERETQIAKGNEQSFR
S97 IAKGNEQSFRVDLRT
C145 EQFAYDGCDYIALNE
Y147 FAYDGCDYIALNEDL
T156 ALNEDLKTWTAADMA
M162 KTWTAADMAALITKH
K170 AALITKHKWEQAGAA
Y183 AAERDRAYLEGTCVE
W191 LEGTCVEWLRRYLEL
Y195 CVEWLRRYLELGNAT
T202 YLELGNATLLHTDSP
K210 LLHTDSPKAHVTHHP
K267-ub AGDGTFQkWASVVVP
S270 GTFQkWASVVVPLGK
- gap
K340 MRRNTGGKGGDYTLT
Y344 TGGKGGDYTLTPGSQ
S350 DYTLTPGSQSsEMsL
S353-p LTPGSQSsEMsLPDC
S356-p GSQSsEMsLPDCKA_
K361 EMsLPDCKA______
  HLAC iso7  
- gap
S366-p VMVHNPHsLA_____
T349-p ALAPGsQtsDLsLPD
- gap
- gap
- gap
T17 LAAALAPTQTRAGPH
N197 RRYLELGNATLLRTD
S25 QTRAGPHSLRYFETA
Y28 AGPHSLRYFETAVSR
T52 EVGYVDDTEFVRFDS
Y80 MEQVEPEYWEEQTQI
I87 YWEEQTQIAKGNEQR
K89 EEQTQIAKGNEQRsR
S95-p AKGNEQRsRVNLRTA
R142 EQVAYDGRDYIALNE
Y144 VAYDGRDYIALNEDL
T153 ALNEDLKTWTAADMA
M159 KTWTAADMAALITKH
K167 AALITKHKWEQAGAA
Y180 AAERRRAYLEGTCVE
W188 LEGTCVEWLRRYLEL
Y192 CVEWLRRYLELGNAT
T199 YLELGNATLLRTDSP
K207 LLRTDSPKAHVTHHS
K264 AGDGTFQKWASVVVP
S267 GTFQKWASVVVPLGK
- gap
K337-ub RRRNTGGkGGDyALA
Y341-p TGGkGGDyALAPGsQ
S347-p DyALAPGsQtsDLsL
S350-p LAPGsQtsDLsLPDC
S353-p GsQtsDLsLPDCKVM
K358 DLsLPDCKVMVHNPH
  HLAC iso21  
- gap
S367-p VMVHDPHsLA_____
T350-p ALAPGsQtsDLsLPD
- gap
- gap
- gap
T17 LAAALAPTQTRAGPH
N197 RRYLKNGNAtLLRTD
S25 QTRAGPHSLRYFVTA
Y28 AGPHSLRYFVTAVSR
T52 EVGYVDDTEFVRFDS
Y80 MEQEGPEYWERETQK
K87 YWERETQKAKGNEQS
K89 ERETQKAKGNEQSFR
S94 KAKGNEQSFRVDLRT
C142 QQYAYDGCDYIALNE
Y144 YAYDGCDYIALNEDL
T153 ALNEDLKTWTAADMA
M159 KTWTAADMAALITKH
K167 AALITKHKWEQAGEA
Y180 EAERLRAYLEGTCVE
W188 LEGTCVEWLRRYLKN
Y192 CVEWLRRYLKNGNAt
T199-p YLKNGNAtLLRTDSP
K207 LLRTDSPKAHVTHHS
K264 AGDGTFQKWASVVVP
S267 GTFQKWASVVVPLGK
- gap
K338-ub RRRNTGGkGGDyALA
Y342-p TGGkGGDyALAPGsQ
S348-p DyALAPGsQtsDLsL
S351-p LAPGsQtsDLsLPDC
S354-p GsQtsDLsLPDCkVM
K359-ub DLsLPDCkVMVHDPH
  HLAC iso22  
- gap
S366-p VMVHDPHsLA_____
T349-p ALAPGsQtsDLsLPD
- gap
- gap
- gap
T17 LAAALAPTQTRAGPH
N197 RRYLELGNETLLRTD
S25 QTRAGPHSLRYFVTA
Y28 AGPHSLRYFVTAVSR
T52 AVGYVDDTQFVRFDS
Y80 MEQEGPEYWEEQTQR
R87 YWEEQTQRAKSDEQW
K89 EEQTQRAKSDEQWFR
W94 RAKSDEQWFRVSLRT
R142 QQFAYDGRDYIALNE
Y144 FAYDGRDYIALNEDL
T153 ALNEDLKTWTAADTA
T159 KTWTAADTAALITRR
K167 AALITRRKWEQAGDA
Y180 DAEYYRAYLEGECVE
W188 LEGECVEWLRRYLEL
Y192 CVEWLRRYLELGNET
T199 YLELGNETLLRTDSP
K207 LLRTDSPKAHVTYHP
K264 AGDGTFQKWAAVVVP
A267 GTFQKWAAVVVPLGK
- gap
K337-ub MRRNTGGkGVNyALA
Y341-p TGGkGVNyALAPGsQ
S347-p NyALAPGsQtsDLsL
S350-p LAPGsQtsDLsLPDG
S353-p GsQtsDLsLPDGKVM
K358 DLsLPDGKVMVHDPH
  HLAC iso23  
- gap
- gap
S355-p ALAPGsQssDMsLPD
- gap
- gap
- gap
T20 LAAALGPTQTRAGSH
N200 RRYLKNGNAtLLRTD
S28 QTRAGSHSLRYFVTA
Y31 AGSHSLRYFVTAVSR
T55 EVGYVDNTEFVRFDS
Y83 IEQEGPEYWERETRR
R90 YWERETRRAKGNEQS
K92 ERETRRAKGNEQSFR
S97 RAKGNEQSFRVDLRT
C145 WQFAYDGCDYIALNE
Y147 FAYDGCDYIALNEDL
T156 ALNEDLKTWTAADMA
M162 KTWTAADMAAQITRR
K170 AAQITRRKWEQAGAA
Y183 AAERDRAYLEGECVE
W191 LEGECVEWLRRYLKN
Y195 CVEWLRRYLKNGNAt
T202-p YLKNGNAtLLRTDPP
K210 LLRTDPPKAHVTHHR
K267 AGDGTFQKWASVVVP
S270 GTFQKWASVVVPLGK
- gap
K343 RRRNTGGKGGDyALA
Y347-p TGGKGGDyALAPGsQ
S353-p DyALAPGsQssDMsL
S356-p LAPGsQssDMsLPDC
S359-p GsQssDMsLPDCKV_
K364 DMsLPDCKV______
  HLAC iso25  
- gap
- gap
T350-p ALAPGsQtsDLsLPD
- gap
- gap
- gap
T17 LAVALAPTQTRAGPH
N197 RRYLELGNATLLRTD
S25 QTRAGPHSLRYFYTT
Y28 AGPHSLRYFYTTVSR
T52 SVGYVDNTEFVRFDS
Y80 MEQEGPEYWERETQK
K87 YWERETQKSKGQKES
K89 ERETQKSKGQKESFR
S94 KSKGQKESFRVDLRT
R142 LQYAYDGRDYIALNE
Y144 YAYDGRDYIALNEDL
T153 ALNEDLKTWTAADMA
M159 KTWTAADMAAQITRH
K167 AAQITRHKWEQAGAA
Y180 AAELYKAYLEGECVE
S188-p LEGECVEsLRRYLEL
Y192 CVEsLRRYLELGNAT
T199 YLELGNATLLRTDSP
K207 LLRTDSPKAHVTHHS
K264 AGDGTFQKWASVVVP
S267 GTFQKWASVVVPLGK
- gap
K338-ub RRRNTGGkGGDyALA
Y342-p TGGkGGDyALAPGsQ
S348-p DyALAPGsQtsDLsL
S351-p LAPGsQtsDLsLPDC
S354-p GsQtsDLsLPDCKA_
K359 DLsLPDCKA______
  HLAC iso26  
- gap
- gap
S352-p ALAPGsQssEMsLRD
- gap
- gap
- gap
T20 LAAALAPTQTRAGPH
N200 HRYLKNGNAtLLRTD
S28 QTRAGPHSMRYFETA
Y31 AGPHSMRYFETAVSR
K55-ub SVGYVDNkEFVRFDS
Y83 MEQEGPEYWERITQI
I90 YWERITQIAKGQEQW
K92 ERITQIAKGQEQWFR
W97 IAKGQEQWFRVNLRT
C145 EQFAYDGCDYIALNE
Y147 FAYDGCDYIALNEDL
T156 ALNEDLKTWTAADMA
M162 KTWTAADMAAQITRR
K170-ub AAQITRRkWEQAGAA
Y183 AAEYYRAYLEGECVE
W191 LEGECVEWLHRYLKN
Y195 CVEWLHRYLKNGNAt
T202-p YLKNGNAtLLRTDSP
K210 LLRTDSPKAHVTHHP
K267 AGDGTFQKWASVVVP
S270 GTFQKWASVVVPLGK
- gap
K340-ub RRRNTGGkGGDyALA
Y344-p TGGkGGDyALAPGsQ
S350-p DyALAPGsQssEMsL
S353-p LAPGsQssEMsLRDC
S356-p GsQssEMsLRDCKA_
K361 EMsLRDCKA______
  HLAC iso27  
- gap
S367 VMVDDPHSLA_____
S350 TLAPGSQSSDMSLPD
- gap
- gap
- gap
T17 LAAALAPTQTRAGPH
N197 RRYLERGNATLLRTD
S25 QTRAGPHSLRYFETA
Y28 AGPHSLRYFETAVSR
T52 SVGYVDNTEFVRFDS
Y80 MEQEGPEYWERETQR
R87 YWERETQRAKGQEQS
K89 ERETQRAKGQEQSFR
S94 RAKGQEQSFRVDLRT
R142 QQHAYDGRDYIALNE
Y144 HAYDGRDYIALNEDL
T153 ALNEDLKTWTAADMA
M159 KTWTAADMAALITKQ
K167 AALITKQKWEQAGAA
Y180 AAERLRAYLEGACVE
W188 LEGACVEWLRRYLER
Y192 CVEWLRRYLERGNAT
T199 YLERGNATLLRTDSP
K207 LLRTDSPKAHVTHHP
K264 AGDGTFQKWAsVVVP
S267-p GTFQKWAsVVVPRGK
- gap
K338 RRRNTGGKGGDYTLA
Y342 TGGKGGDYTLAPGSQ
S348 DYTLAPGSQSSDMSL
S351 LAPGSQSSDMSLPDC
S354 GSQSSDMSLPDCKVM
K359 DMSLPDCKVMVDDPH
  rat

► Hide Isoforms
 
- gap
- gap
S336 PSRDSSESSDVSLSD
- gap
- gap
- gap
- gap
K176 LRYLELGKETLLRSD
S4 ____GSHSLRYFVTA
- under review  
T31 EVGYVDDTEFVRYDS
Y59 MEREGREYWERETRI
I66 YWERETRIAKGNEQT
K68 ERETRIAKGNEQTFR
T73 IAKGNEQTFRENLRT
R121 EQFAYDGRDYIVLNE
Y123 FAYDGRDYIVLNEDL
T132 VLNEDLKTWTAADTA
T138 KTWTAADTAARITRN
K146 AARITRNKWDRAGVA
Y159 VAERHKAYLEGKCLE
S167 LEGKCLESLLRYLEL
Y171 CLESLLRYLELGKET
T178 YLELGKETLLRSDPP
K186 LLRSDPPKAHVTLHP
K243 AGDGTFQKWASVVVP
S246 GTFQKWASVVVPLGK
- gap
K321 RRRNTGGKVGVyAPA
Y325-p TGGKVGVyAPAPSRD
S334 PAPSRDSSESSDVSL
S337 SRDSSESSDVSLSDC
S340 SSESSDVSLSDCKA_
K345 DVSLSDCKA______
  HLAC iso1  
- gap
- gap
S359 PGTDSSQSsDVsLPD
- gap
- gap
- gap
T20-p LAAALAPtQTRAGSH
K200 RRYLELGKETLLRSD
S28-p QTRAGSHsMRYFDIA
Y31 AGSHsMRYFDIAVSR
T55 IVGYVDDTEFVRFDS
Y83 MEPEGPEYWEEQTRR
R90 YWEEQTRRAKEGEQT
K92 EEQTRRAKEGEQTFR
T97 RAKEGEQTFRVNLRT
R145 EQYAYDGRDYIALNE
Y147 YAYDGRDYIALNEDL
T156 ALNEDLKTWTAADFA
F162 KTWTAADFAARISRN
K170 AARISRNKWDQAGVA
Y183 VAERLRAYLEGECVE
W191 LEGECVEWLRRYLEL
Y195 CVEWLRRYLELGKET
T202 YLELGKETLLRSDPP
K210 LLRSDPPKAHVTLHP
K267 AGDGTFQKWASVVVP
S270 GTFQKWASVVVPLGK
- gap
K345 RRRNTGGKGVYTPAP
Y348 NTGGKGVYTPAPGTD
S357 PAPGTDSSQSsDVsL
S360-p GTDSSQSsDVsLPDC
S363-p SSQSsDVsLPDCKA_
K368 DVsLPDCKA______
  HLAC iso3  
- gap
- gap
S359 RGRDSSQSsDVsLPD
- gap
- gap
- gap
T17 LAAALAPTQTQAGSH
K197 RSYLAPRKETLLRSD
S25 QTQAGSHSLRYFDIA
Y28 AGSHSLRYFDIAVSR
R52 IVGYVDDREVMRFDS
Y80 MEREGPEYWERQTRK
K87 YWERQTRKVKEKEQI
K89 ERQTRKVKEKEQIFR
I94 KVKEKEQIFRDNLRT
R142 NQHAYDGRDyIALNE
Y144-p HAYDGRDyIALNEDL
T153-p ALNEDLKtWTAADTA
T159 KtWTAADTAAQITKN
K167 AAQITKNKWERDGEA
Y180 EAERRRAYLEGECVE
W188 LEGECVEWLRSYLAP
Y192 CVEWLRSYLAPRKET
T199 YLAPRKETLLRSDPP
K207 LLRSDPPKAHVTLHP
K264 AGDGTFQKWASVVVP
S267 GTFQKWASVVVPSGE
- gap
K345 RRRNTGGKGDYTPAR
Y348 NTGGKGDYTPARGRD
S357 PARGRDSSQSsDVsL
S360-p GRDSSQSsDVsLPDC
S363-p SSQSsDVsLPDCKA_
K368 DVsLPDCKA______
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.