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ADH1B (human)

Overview ADH1B Dimer of identical or non-identical chains of three types; alpha, beta and gamma. Belongs to the zinc-containing alcohol dehydrogenase family. Note: This description may include information from UniProtKB. Protein type: Cofactor and Vitamin Metabolism - retinol; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Lipid Metabolism - fatty acid; EC 1.1.1.1; Amino Acid Metabolism - tyrosine; Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase Cellular Component: cytosol Molecular Function: zinc ion binding; nucleotide binding; alcohol dehydrogenase activity, zinc-dependent Biological Process: xenobiotic metabolic process; ethanol oxidation Reference #:  P00325 (UniProtKB) Alt. Names/Synonyms: ADH, beta subunit; ADH1B; ADH2; Alcohol dehydrogenase 1B; alcohol dehydrogenase 1B (class I), beta polypeptide; alcohol dehydrogenase 2 (class I), beta polypeptide; Alcohol dehydrogenase subunit beta; aldehyde reductase; DKFZp686C06125 Gene Symbols: ADH1B Molecular weight: 39,855 Da Basal Isoelectric point: 8.63  Predict pI for various phosphorylation states Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below ADH1B 1DEH - A/B=1-375 (human) 1HDX - A/B=1-375 (human) 1HDY - A/B=1-375 (human) 1HDZ - A/B=1-375 (human) 1HSZ - A/B=1-375 (human) 1HTB - A/B=1-375 (human) 1U3U - A/B=1-375 (human) 1U3V - A/B=1-375 (human) 3HUD - A/B=1-375 (human)

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD  |  ENZYME  |  Phospho3D  |  DISEASE 103720 103780  |  Source  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	5		S23-p	WEVKKPFsIEDVEVA
0	340		Y35-p	EVAPPKAyEVRIKMV
0	1		K100-a	LFTPQCGkCRVCKNP
0	31		Y111-p	CKNPESNyCLKNDLG
0	197		Y150-p	GTSTFSQytVVDENA
0	3		T151-p	TSTFSQytVVDENAV
0	1		Y181-p	GCGFSTGyGSAVNVA
0	1		K213-a	LSAVMGCkAAGAARI
0	11		Y247-p	ECINPQDyKKPIQEV
0	3		Y320-p	RTWKGAVyGGFKSKE
0	1		K331-a	KSKEGIPkLVADFMA
0	11		K339-a	LVADFMAkKFSLDAL
0	1		K355-a	THVLPFEkINEGFDL
0	2		K367-a	FDLLHSGkSIRTVLT

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