Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; Secreted, signal peptide; Cytokine; Apoptosis; Secreted; Oncoprotein
Cellular Component: extracellular space; extracellular region
Biological Process: myeloid cell apoptosis; regulation of protein amino acid dephosphorylation; negative regulation of autophagy; activation of JAK protein; cytokine and chemokine mediated signaling pathway; response to hormone stimulus; positive regulation of JNK cascade; positive regulation of peptidyl-tyrosine phosphorylation; regulation of gene expression; negative regulation of mast cell apoptosis; regulation of glycolysis; positive regulation of cell proliferation; response to hypoxia; immune response; hemopoiesis; positive regulation of protein amino acid phosphorylation; regulation of cell growth; positive regulation of myeloid leukocyte differentiation; negative regulation of apoptosis