Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
IL3 (mouse)

IL3 Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; Secreted, signal peptide; Cytokine; Apoptosis; Secreted; Oncoprotein
Cellular Component: extracellular space; extracellular region
Molecular Function: interleukin-3 receptor binding; growth factor activity; cytokine activity
Biological Process: myeloid cell apoptosis; regulation of protein amino acid dephosphorylation; negative regulation of autophagy; activation of JAK protein; cytokine and chemokine mediated signaling pathway; response to hormone stimulus; positive regulation of JNK cascade; positive regulation of peptidyl-tyrosine phosphorylation; regulation of gene expression; negative regulation of mast cell apoptosis; regulation of glycolysis; positive regulation of cell proliferation; response to hypoxia; immune response; hemopoiesis; positive regulation of protein amino acid phosphorylation; regulation of cell growth; positive regulation of myeloid leukocyte differentiation; negative regulation of apoptosis
Reference #:  P01586 (UniProtKB)
Alt. Names/Synonyms: BPA; Csfmu; HCGF; Hematopoietic growth factor; IL-3; Il3; interleukin 3; Interleukin-3; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; OTTMUSP00000005831; P-cell-stimulating factor; PSF
Gene Symbols: Il3
Molecular weight: 18,540 Da
Basal Isoelectric point: 8.39  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

STRING  |  Reactome  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

Modification Sites and Domains  

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.