Home

NDRG3 (human)

Overview NDRG3 sequence is similar to alpha/beta hydrolases. During development, NDRG3 is expressed at high levels in the spinal cord and the thymic rudiment. NDRG3 is located throughout the mouse cerebrum and cerebellum. NDRG1 and NDRG3 belong to a subfamily, and NDRG2 and NDRG4 to another. In humans, NDRG3 is highly expressed in brain and testis. Unlike Ndr1, Ndr2 and Ndr3 appear not to be controlled by N-myc or c-myc. Three alternately spliced human isoforms have been reported. Note: This description may include information from UniProtKB. Protein type: Cell development/differentiation Cellular Component: cytoplasm Biological Process: spermatogenesis; negative regulation of cell growth; cell differentiation Reference #:  Q9UGV2 (UniProtKB) Alt. Names/Synonyms: FLJ13556; N-myc downstream-regulated gene 3; NDRG family member 3; NDRG3; Protein NDRG3 Gene Symbols: NDRG3 Molecular weight: 41,409 Da Basal Isoelectric point: 5.12  Predict pI for various phosphorylation states Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below NDRG3

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  DISEASE  |  Source  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		K13-u	DVQLTEIkPLLNDKN
0	1		K19	IkPLLNDKNGTRNFQ
0	1		K51	VTIRGLPKGNRPVIL
0	1		Y308-p	KLTEAFKyFLQGMGY
0	7		Y315	yFLQGMGYIPsAsMt
0	2		S318-p	QGMGYIPsAsMtRLA
0	4		S320-p	MGYIPsAsMtRLARs
0	3		T322-p	YIPsAsMtRLARsRt
0	187		S327-p	sMtRLARsRtHstss
0	148		T329-p	tRLARsRtHstsssL
0	633		S331-p	LARsRtHstsssLGs
0	160		T332-p	ARsRtHstsssLGsG
0	165		S333-p	RsRtHstsssLGsGE
0	375		S334-p	sRtHstsssLGsGEs
0	402		S335-p	RtHstsssLGsGEsP
0	77		S338-p	stsssLGsGEsPFsR
0	22		S341-p	ssLGsGEsPFsRsVt
0	2		S344-p	GsGEsPFsRsVtsNQ
0	5		S346-p	GEsPFsRsVtsNQsD
0	11		T348-p	sPFsRsVtsNQsDGt
0	11		S349-p	PFsRsVtsNQsDGtQ
0	31		S352-p	RsVtsNQsDGtQESC
0	11		T355-p	tsNQsDGtQESCEsP
0	3		S358	QsDGtQESCEsPDVL
0	89		S361-p	GtQESCEsPDVLDRH
0	18		T370-p	DVLDRHQtMEVsC__
0	4		S374-p	RHQtMEVsC______

	mouse
K13	DVQLTEIKPLLNDkN
K19-u	IKPLLNDkNGTRNFQ
K51-u	VTIRGLPkGNRPVIL
Y308	KLTEAFKYFLQGMGY
Y315	YFLQGMGYIPsAsMt
S318-p	QGMGYIPsAsMtRLA
S320-p	MGYIPsAsMtRLARs
T322-p	YIPsAsMtRLARsRt
S327-p	sMtRLARsRtHstss
T329-p	tRLARsRtHstsssI
S331-p	LARsRtHstsssIGs
T332-p	ARsRtHstsssIGsG
S333-p	RsRtHstsssIGsGE
S334-p	sRtHstsssIGsGEs
S335-p	RtHstsssIGsGEsP
S338-p	stsssIGsGEsPFSR
S341-p	ssIGsGEsPFSRsVt
S344	GsGEsPFSRsVtSNQ
S346-p	GEsPFSRsVtSNQsD
T348-p	sPFSRsVtSNQsDGt
S349	PFSRsVtSNQsDGtQ
S352-p	RsVtSNQsDGtQEsC
T355-p	tSNQsDGtQEsCEsP
S358-p	QsDGtQEsCEsPDVL
S361-p	GtQEsCEsPDVLDRH
T370	DVLDRHQTMEVsC__
S374-p	RHQTMEVsC______

	rat
K13	DVQLTEIKPLLNDKN
K19	IKPLLNDKNGTRNFQ
K51	VTIRGLPKGNRPVIL
Y308	KLTEAFKYFLQGMGy
Y315-p	YFLQGMGyIPSASMT
S318	QGMGyIPSASMTRLA
S320	MGyIPSASMTRLARS
T322	yIPSASMTRLARSRT
S327	SMTRLARSRTHSTSS
T329	TRLARSRTHSTSSSI
S331	LARSRTHSTSSSIGS
T332	ARSRTHSTSSSIGSG
S333	RSRTHSTSSSIGSGE
S334	SRTHSTSSSIGSGES
S335	RTHSTSSSIGSGESP
S338	STSSSIGSGESPFSR
S341	SSIGSGESPFSRSVT
S344	GSGESPFSRSVTSNQ
S346	GESPFSRSVTSNQSD
T348	SPFSRSVTSNQSDGT
S349	PFSRSVTSNQSDGTQ
S352	RSVTSNQSDGTQESC
T355	TSNQSDGTQESCESP
S358	QSDGTQESCESPDVL
S361	GTQESCESPDVLDRH
T370	DVLDRHQTMEVSC__
S374	RHQTMEVSC______

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E Produced by 3rd Millennium  |  Design by Digizyme ©2003-2013 Cell Signaling Technology, Inc.