a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Nuclear receptor; DNA binding protein; Transcription factor
Molecular Function: protein dimerization activity; identical protein binding; ligand-dependent nuclear receptor activity; zinc ion binding; androgen binding; beta-catenin binding; transcription factor binding; androgen receptor activity; protein binding; enzyme binding; DNA binding; androgen receptor binding; sequence-specific DNA binding; chromatin binding; transcription factor activity; receptor binding
Biological Process: cell death; prostate gland development; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of estrogen receptor signaling pathway; signal transduction; response to insulin stimulus; activation of NF-kappaB transcription factor; negative regulation of integrin biosynthetic process; positive regulation of MAPKKK cascade; cell-cell signaling; transport; regulation of catalytic activity; positive regulation of cell proliferation; male genitalia morphogenesis; positive regulation of integrin biosynthetic process; cell growth; negative regulation of epithelial cell proliferation; transcription initiation from RNA polymerase II promoter; regulation of developmental growth; organ formation; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; in utero embryonic development; male gonad development; protein oligomerization; cell proliferation; androgen receptor signaling pathway; positive regulation of transcription from RNA polymerase III promoter; gene expression; positive regulation of transcription from RNA polymerase II promoter; male somatic sex determination; sex differentiation; positive regulation of phosphorylation; negative regulation of apoptosis
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.