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Protein Page:
RanBP1 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
RanBP1 Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane. Belongs to the RANBP1 family. Note: This description may include information from UniProtKB.
Protein type: G protein regulator, misc.
Cellular Component: centrosome; cytoplasm; nuclear envelope; nucleus
Molecular Function: GDP-dissociation inhibitor activity; Ran GTPase binding; GTPase activator activity
Biological Process: positive regulation of mitotic centrosome separation; intracellular transport; viral reproduction; regulation of catalytic activity; signal transduction; spindle organization and biogenesis
Reference #:  P43487 (UniProtKB)
Alt. Names/Synonyms: HTF9A; MGC88701; RAN binding protein 1; Ran-binding protein 1; Ran-specific GTPase-activating protein; RANBP1; RANG
Gene Symbols: RANBP1
Molecular weight: 23,310 Da
Basal Isoelectric point: 5.19  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

RanBP1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T7-p _MAAAKDtHEDHDts
0 5 T13-p DtHEDHDtstENtDE
0 9 S14-p tHEDHDtstENtDEs
0 4 T15-p HEDHDtstENtDEsN
0 7 T18-p HDtstENtDEsNHDP
0 4 S21-p stENtDEsNHDPQFE
0 8 K50-u EDEEELFkMRAKLFR
0 176 S60-p AKLFRFAsENDLPEW
0 15 K68-u ENDLPEWkERGTGDV
0 7 K76-u ERGTGDVkLLKHKEK
0 85 Y103-p LKICANHyItPMMEL
0 15 T105-p ICANHyItPMMELkP
0 1 K111-a ItPMMELkPNAGSDR
0 2 K111-u ItPMMELkPNAGSDR
0 6 K134-a DFADECPkPELLAIR
0 2 K134-u DFADECPkPELLAIR
0 21 K150-a LNAENAQkFkTkFEE
0 23 K150-u LNAENAQkFkTkFEE
0 3 K152-a AENAQkFkTkFEECR
0 8 K154-a NAQkFkTkFEECRkE
0 3 K160-a TkFEECRkEIEEREK
0 12 K183-a HAEKVAEkLEALsVk
0 4 K183-u HAEKVAEkLEALsVk
0 1 S188-p AEkLEALsVkEETKE
0 7 K190-a kLEALsVkEETKEDA
  mouse

 
S7-p _MAAAKDsHEDHDts
T13-p DsHEDHDtstENADE
S14-p sHEDHDtstENADEs
T15-p HEDHDtstENADEsN
A18 HDtstENADEsNHDP
S21-p stENADEsNHDPQFE
K50-u EDEEELFkMRAKLFR
S60-p AKLFRFAsENDLPEW
K68-u ENDLPEWkERGTGDV
K76 ERGTGDVKLLKHKEK
Y103-p LKICANHyITPMMEL
T105 ICANHyITPMMELKP
K111 ITPMMELKPNAGSDR
K111 ITPMMELKPNAGSDR
K134 DFADECPKPELLAIR
K134 DFADECPKPELLAIR
K150-a LNAENAQkFKTKFEE
K150-u LNAENAQkFKTKFEE
K152 AENAQkFKTKFEECR
K154 NAQkFKTKFEECRKE
K160 TKFEECRKEIEEREK
K182 NAEKVAEKLEALSVR
K182 NAEKVAEKLEALSVR
S187 AEKLEALSVREAREE
R189 KLEALSVREAREEAE
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