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Protein Page:
UBE2B (human)

UBE2B a ubiquitin-protein ligase, a member of the ubiquitin-conjugating enzyme family. Homologous to the yeast DNA repair gene RAD6. Interacts with RAD18. Required for postreplication repair of UV-damaged DNA.. Note: This description may include information from UniProtKB.
Protein type: Ligase; Ubiquitin ligase; EC; Ubiquitin conjugating system
Cellular Component: XY body; nuclear chromatin; cytoplasm; plasma membrane; replication fork; nucleus; chromatin
Molecular Function: protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ATP binding
Biological Process: ubiquitin-dependent protein catabolic process; response to drug; protein monoubiquitination; proteasomal ubiquitin-dependent protein catabolic process; protein autoubiquitination; protein polyubiquitination; protein stabilization; in utero embryonic development; postreplication repair; protein ubiquitination; Wnt receptor signaling pathway through beta-catenin; DNA repair; negative regulation of histone phosphorylation; cellular response to insulin stimulus; response to hypoxia; maintenance of chromatin silencing; sperm axoneme assembly; spermatogenesis; chiasma formation; response to DNA damage stimulus; histone H2A ubiquitination; negative regulation of apoptosis; response to UV
Reference #:  P63146 (UniProtKB)
Alt. Names/Synonyms: E2 protein; E2-17kDa; hHR6B; HR6B; RAD6 homolog B; RAD6B; UBC2; UBE2B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2 B; Ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2B (RAD6 homolog); Ubiquitin-protein ligase B
Gene Symbols: UBE2B
Molecular weight: 17,312 Da
Basal Isoelectric point: 4.91  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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