Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
UBE2B (human)

Overview
UBE2B a ubiquitin-protein ligase, a member of the ubiquitin-conjugating enzyme family. Homologous to the yeast DNA repair gene RAD6. Interacts with RAD18. Required for postreplication repair of UV-damaged DNA.. Note: This description may include information from UniProtKB.
Protein type: Ligase; Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system
Cellular Component: XY body; nuclear chromatin; cytoplasm; plasma membrane; replication fork; nucleus; chromatin
Molecular Function: protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ATP binding
Biological Process: ubiquitin-dependent protein catabolic process; response to drug; protein monoubiquitination; proteasomal ubiquitin-dependent protein catabolic process; protein autoubiquitination; protein polyubiquitination; protein stabilization; in utero embryonic development; postreplication repair; protein ubiquitination; Wnt receptor signaling pathway through beta-catenin; DNA repair; negative regulation of histone phosphorylation; cellular response to insulin stimulus; response to hypoxia; maintenance of chromatin silencing; sperm axoneme assembly; spermatogenesis; chiasma formation; response to DNA damage stimulus; histone H2A ubiquitination; negative regulation of apoptosis; response to UV
Reference #:  P63146 (UniProtKB)
Alt. Names/Synonyms: E2 protein; E2-17kDa; hHR6B; HR6B; RAD6 homolog B; RAD6B; UBC2; UBE2B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2 B; Ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2B (RAD6 homolog); Ubiquitin-protein ligase B
Gene Symbols: UBE2B
Molecular weight: 17,312 Da
Basal Isoelectric point: 4.91  Predict pI for various phosphorylation states
Select Structure to View Below

UBE2B

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Source  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Modification Sites and Domains  

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.