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ARHGAP42 (human)

Overview ARHGAP42 May act as a GTPase activator. Note: This description may include information from UniProtKB. Protein type: GTPase activating protein, misc. Cellular Component: intracellular Molecular Function: phospholipid binding; cytoskeletal adaptor activity; SH3 domain binding; GTPase activator activity Biological Process: filopodium formation; signal transduction Reference #:  A6NI28 (UniProtKB) Alt. Names/Synonyms: FLJ32810; KIAA0621; rho GTPase-activating protein 10-like; Rho GTPase-activating protein FLJ32810; Rho-type GTPase-activating protein FLJ32810; YK021 Gene Symbols: ARHGAP42 Molecular weight: 98,569 Da Basal Isoelectric point: 8.18  Predict pI for various phosphorylation states

Select Structure to View Below ARHGAP42

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human ► Hide Isoforms
0	1		T32-p	HEIELERtNKFIKEL
0	2		K128-a	KEQIGAAkDGkKKFD
0	2		K131-a	IGAAkDGkKKFDKES
0	1		Y142-p	DKESEKYySILEKHL
0	1		T332-p	KSCIRRKtDSIDKRF
0	258		Y376-p	MDGKEPIytLPAIIS
0	23		T377-p	DGKEPIytLPAIISK
0	1		K458	KTITSGLKNYLRCLA
0	1		S714	VTSPGDVSPPIDLVK
0	1		S728-p	KKEPYGLsGLKRASA
0	1		S737	LKRASASSLRsIsAA
0	2		S740-p	ASASSLRsIsAAEGN
0	1		S742-p	ASSLRsIsAAEGNKs
0	1		S749-p	sAAEGNKsYsGSIQS
0	2		S751-p	AEGNKsYsGSIQSLT
0	1		S753	GNKsYsGSIQSLTSV
0	2		S756	sYsGSIQSLTSVGSK
0	1		S759	GSIQSLTSVGSKETP
0	1		S762	QSLTSVGSKETPKAs
0	1		S769-p	SKETPKAsPNPDLPP
0	5		T786-p	CRRLRLDtAssNGyQ
0	15		S788-p	RLRLDtAssNGyQRP
0	30		S789-p	LRLDtAssNGyQRPG
0	654		Y792-p	DtAssNGyQRPGsVV
0	14		S797-p	NGyQRPGsVVAAKAQ
0	1		S811-p	QLFENVGsPKPVSSG
0	1		Y870-p	TGLVPENyVVFL___

	ARHGAP42 iso2
T32	HEIELERTNKFIKEL
K128	KEQIGAAKADTQIDR
-	gap
-	gap
T265	KSCIRRKTDSIDKRF
Y309	MDGKEPIYTLPTIIS
T310	DGKEPIYTLPTIISK
K391	KTITSGLKNYLRCLA
S647	VTSPGDVSPPIDLVK
S661	KKEPYGLSGLKRASA
S670	LKRASASSLRSISAA
S673	ASASSLRSISAAEGN
S675	ASSLRSISAAEGNKS
S682	SAAEGNKSYSGSIQS
S684	AEGNKSYSGSIQSLT
S686	GNKSYSGSIQSLTSV
S689	SYSGSIQSLTSVGSK
S692	GSIQSLTSVGSKETP
S695	QSLTSVGSKETPKAS
S702	SKETPKASPNPDLPP
T719	CRRLRLDTASSNGYQ
S721	RLRLDTASSNGYQRP
S722	LRLDTASSNGYQRPG
Y725	DTASSNGYQRPGSIV
S730	NGYQRPGSIVAAKAQ
S744	QLFENVGSPKPVSSG
-	gap

	mouse
T32	HEIELERTNKFIKEL
K128	KEQIGAAKADSQIGR
-	gap
-	gap
T298	KSCIRRKTDSIDKRF
Y342-p	MDGKEPIytLPAIIS
T343-p	DGKEPIytLPAIISK
K424-u	KTITSGLkNYLRCLA
S680-p	ITIPGNVsPPIDLVK
S694	KKGPYGLSGLKRSSA
S704-p	KRSSASSsLRsISAA
S707-p	SASSsLRsISAAEGN
S709	SSsLRsISAAEGNKS
S716	SAAEGNKSYsGsIQs
S718-p	AEGNKSYsGsIQsLT
S720-p	GNKSYsGsIQsLTSI
S723-p	SYsGsIQsLTSIGSK
S726	GsIQsLTSIGSKESP
S729	QsLTSIGSKESPKAI
I736	SKESPKAIPNPELPP
T753	CRRLRLDTAssNGyQ
S755-p	RLRLDTAssNGyQRP
S756-p	LRLDTAssNGyQRPG
Y759-p	DTAssNGyQRPGsVV
S764-p	NGyQRPGsVVAAKAQ
S778	QLFENAGSPKPVSSG
Y837	TGLVPENYVVFL___

	rat
T32	HEIELERTNKFIKEL
K128	KEQIGAAKDGKKKFD
K131	IGAAKDGKKKFDKES
Y142	DKESEKYYSILDKHL
T332	KSCIRRKTDSIDKRF
Y376-p	MDGKEPIyTLPAIIS
T377	DGKEPIyTLPAIISK
K458	KTITSGLKNYLRCLA
S714	VTSPGDVSPPIDLVK
S728	KKGPYGLSGLKRSSA
S738	KRSSASSSLRSISAA
S741	SASSSLRSISAAEGN
S743	SSSLRSISAAEGNKS
S750	SAAEGNKSYsGSIQS
S752-p	AEGNKSYsGSIQSLT
S754	GNKSYsGSIQSLTsI
S757	SYsGSIQSLTsIGsK
S760-p	GSIQSLTsIGsKESP
S763-p	QSLTsIGsKESPKAT
T770	sKESPKATPNPELPP
T787	CRRLRLDTASSNGYQ
S789	RLRLDTASSNGYQRP
S790	LRLDTASSNGYQRPG
Y793	DTASSNGYQRPGSVV
S798	NGYQRPGSVVAAKAQ
S812	QLFENAGSLKPVSSG
Y871	TGLVPENYVVFL___

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