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Protein Page:
ARHGAP42 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
ARHGAP42 May act as a GTPase activator. Note: This description may include information from UniProtKB.
Protein type: GAPs; GAPs, Rac/Rho
Cellular Component: intracellular
Molecular Function: GTPase activator activity
Biological Process: signal transduction; positive regulation of GTPase activity
Reference #:  A6NI28 (UniProtKB)
Alt. Names/Synonyms: FLJ32810; KIAA0621; rho GTPase-activating protein 10-like; Rho GTPase-activating protein FLJ32810; Rho-type GTPase-activating protein FLJ32810; YK021
Gene Symbols: ARHGAP42
Molecular weight: 98,569 Da
Basal Isoelectric point: 8.18  Predict pI for various phosphorylation states
Select Structure to View Below

ARHGAP42

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T32-p HEIELERtNKFIKEL
0 2 K128-ac KEQIGAAkDGkKKFD
0 2 K131-ac IGAAkDGkKKFDKES
0 1 Y142-p DKESEKYySILEKHL
0 1 S326 PEMFKLKSCIRRKtD
0 1 T332-p KSCIRRKtDSIDKRF
0 236 Y376-p MDGKEPIytLPAIIS
0 20 T377-p DGKEPIytLPAIISK
0 1 K458 KTITSGLKNYLRCLA
0 2 S683-p SLGLWTTsPESSSRE
0 1 S714 VTSPGDVSPPIDLVK
0 1 S728-p KKEPYGLsGLKRASA
0 1 S737 LKRASASSLRsIsAA
0 2 S740-p ASASSLRsIsAAEGN
0 1 S742-p ASSLRsIsAAEGNKs
0 1 S749-p sAAEGNKsYsGSIQS
0 2 S751-p AEGNKsYsGSIQSLT
0 2 S753 GNKsYsGSIQSLTSV
0 3 S756 sYsGSIQSLTSVGSK
0 1 S759 GSIQSLTSVGSKETP
0 1 S762 QSLTSVGSKETPKAs
0 1 S769-p SKETPKAsPNPDLPP
0 5 T786-p CRRLRLDtAssNGyQ
0 14 S788-p RLRLDtAssNGyQRP
0 28 S789-p LRLDtAssNGyQRPG
0 637 Y792-p DtAssNGyQRPGsVV
0 14 S797-p NGyQRPGsVVAAKAQ
0 2 S811-p QLFENVGsPKPVSSG
0 1 Y870-p TGLVPENyVVFL___
  mouse

 
T32 HEIELERTNKFIKEL
K128 KEQIGAAKADSQIGR
- gap
- gap
S292-p PEMFKLKsCIRRKTD
T298 KsCIRRKTDSIDKRF
Y342-p MDGKEPIytLPAIIS
T343-p DGKEPIytLPAIISK
K424-ub KTITSGLkNYLRCLA
S649-p SQGLWTTsPESSSRE
S680-p ITIPGNVsPPIDLVK
S694 KKGPYGLSGLKRSSA
S704-p KRSSASSsLRsISAA
S707-p SASSsLRsISAAEGN
S709 SSsLRsISAAEGNKS
S716 SAAEGNKSYsGsIQs
S718-p AEGNKSYsGsIQsLT
S720-p GNKSYsGsIQsLTSI
S723-p SYsGsIQsLTSIGSK
S726 GsIQsLTSIGSKESP
S729 QsLTSIGSKESPKAI
I736 SKESPKAIPNPELPP
T753 CRRLRLDTAssNGyQ
S755-p RLRLDTAssNGyQRP
S756-p LRLDTAssNGyQRPG
Y759-p DTAssNGyQRPGsVV
S764-p NGyQRPGsVVAAKAQ
S778 QLFENAGSPKPVSSG
Y837 TGLVPENYVVFL___
  rat

 
T32 HEIELERTNKFIKEL
K128 KEQIGAAKDGKKKFD
K131 IGAAKDGKKKFDKES
Y142 DKESEKYYSILDKHL
S326 PEMFKLKSCIRRKTD
T332 KSCIRRKTDSIDKRF
Y376-p MDGKEPIyTLPAIIS
T377 DGKEPIyTLPAIISK
K458 KTITSGLKNYLRCLA
S683 SLGLWTTSPESSSRE
S714 VTSPGDVSPPIDLVK
S728 KKGPYGLSGLKRSSA
S738 KRSSASSSLRSISAA
S741 SASSSLRSISAAEGN
S743 SSSLRSISAAEGNKS
S750 SAAEGNKSYsGSIQS
S752-p AEGNKSYsGSIQSLT
S754 GNKSYsGSIQSLTsI
S757 SYsGSIQSLTsIGsK
S760-p GSIQSLTsIGsKESP
S763-p QSLTsIGsKESPKAT
T770 sKESPKATPNPELPP
T787 CRRLRLDTASSNGYQ
S789 RLRLDTASSNGYQRP
S790 LRLDTASSNGYQRPG
Y793 DTASSNGYQRPGSVV
S798 NGYQRPGSVVAAKAQ
S812 QLFENAGSLKPVSSG
Y871 TGLVPENYVVFL___
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