a non-receptor protein-tyrosine kinases of the Tec family. Containing a pleckstrin homology domain. Involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. May be an important signal transducer for cell division and/or for differentiation in the liver system. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, tyrosine (non-receptor); EC 188.8.131.52; Kinase, protein; Protein kinase, TK; TK group; Tec family
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.