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Protein Page:
SNIP (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
SNIP Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. Interacts with the N-terminal coiled-coil region of SNAP25. Interacts with BCAR1/p130Cas and SRC through its C-terminal domain. Interacts with CSK, CTTN, SORBS3/vinexin, SYP and MAPRE3/EB3. Expressed in some primary breast carcinomas where its presence is significantly associated with increased tumor size. Not detected in normal breast tissue. Belongs to the SRCIN1 family. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal protein
Cellular Component: postsynaptic membrane; focal adhesion; cell soma; lamellipodium; axon; cytoplasm; postsynaptic density; dendrite; synapse; actin cytoskeleton; filopodium
Molecular Function: protein domain specific binding; protein binding; protein kinase binding
Biological Process: negative regulation of protein secretion; exocytosis; negative regulation of cell adhesion; regulation of cell migration
Reference #:  Q9C0H9 (UniProtKB)
Alt. Names/Synonyms: KIAA1684; p130Cas-associated protein; P140; p140Cap; SNAP-25-interacting protein; SNAP25-interacting protein; SNIP; SRC kinase signaling inhibitor 1; SRCIN1; SRCN1
Gene Symbols: SRCIN1
Molecular weight: 112,453 Da
Basal Isoelectric point: 9.32  Predict pI for various phosphorylation states
CST Pathways:  Adherens Junction Dynamics
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

SNIP

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 - gap
0 4 - gap
0 6 - gap
0 2 - gap
0 1 - gap
1 23 - gap
0 4 - gap
0 8 - gap
0 2 - gap
0 9 - gap
0 1 - gap
0 1 - gap
0 3 - gap
0 2 - gap
0 1 - gap
0 7 - gap
0 3 - gap
0 1 - gap
0 1 - gap
0 1 - gap
0 3 - gap
0 6 - gap
0 1 - gap
0 16 - gap
0 4 - gap
0 1 - gap
0 4 - gap
0 1 T91 HMFPQKLTMGMLKSP
0 8 S97 LTMGMLKSPNtAILI
0 3 T100-p GMLKSPNtAILIKDE
0 5 K105 PNtAILIKDEARNVF
0 30 Y113 DEARNVFYELEDVRD
0 5 K128 IQDRSIIKIYRKEPL
0 7 Y130 DRSIIKIYRKEPLyA
1 95 Y136-p IYRKEPLyAAFPGSH
0 6 Y155-p DLRREMVyASRESSP
0 3 S157 RREMVyASRESSPTR
0 2 S160 MVyASRESSPTRRLN
0 4 S161 VyASRESSPTRRLNN
0 2 S170 TRRLNNLSPAPHLAS
0 1 P173 LNNLSPAPHLASGsP
0 1 S177 SPAPHLASGsPPPGL
0 3 S179-p APHLASGsPPPGLPS
0 2 S190-p GLPSGLPsGLQSGSP
0 1 S194 GLPsGLQSGSPSRsR
0 2 S196 PsGLQSGSPSRsRLs
0 1 S198 GLQSGSPSRsRLsyA
0 1 S200-p QSGSPSRsRLsyAGG
0 1 R201 SGSPSRsRLsyAGGR
0 2 S203-p SPSRsRLsyAGGRPP
0 5 Y204-p PSRsRLsyAGGRPPs
0 1 R208 RLsyAGGRPPsyAGs
0 17 S211-p yAGGRPPsyAGsPVH
0 6 Y212-p AGGRPPsyAGsPVHH
0 15 S215-p RPPsyAGsPVHHAAE
0 1 A229 ERLGGAPAAQGVSPs
0 1 A230 RLGGAPAAQGVSPsP
0 6 S234 APAAQGVSPsPsAIL
0 5 S236-p AAQGVSPsPsAILER
0 3 S238-p QGVSPsPsAILERRD
0 2 K247 ILERRDVKPDEDLAS
0 4 K263 AGGMVLVKGEGLyAD
1 208 Y268-p LVKGEGLyADPyGLL
0 43 Y272-p EGLyADPyGLLHEGR
0 1 S281-p LLHEGRLsLAAAAGD
0 3 Y299 YPGAGGLYKRGSVRS
0 3 K300 PGAGGLYKRGSVRSL
0 1 K325 DLEDSLYKAAGGGGP
0 22 Y334-p AGGGGPLyGDGYGFR
0 1 S346-p GFRLPPSsPQKLADV
0 1 A354 PQKLADVAAPPGGPP
0 3 P357 LADVAAPPGGPPPPH
0 5 S365 GGPPPPHSPYSGPPs
0 4 Y367 PPPPHSPYSGPPsRG
0 3 S368 PPPHSPYSGPPsRGs
0 9 S372-p SPYSGPPsRGsPVRQ
0 1 R373 PYSGPPsRGsPVRQs
0 8 S375-p SGPPsRGsPVRQsFR
0 4 S380-p RGsPVRQsFRKDsGs
0 9 S385-p RQsFRKDsGsSsVFA
0 3 S387-p sFRKDsGsSsVFAEs
0 1 S388 FRKDsGsSsVFAEsP
0 3 S389-p RKDsGsSsVFAEsPG
0 12 S394-p sSsVFAEsPGGKTRS
0 1 K398 FAEsPGGKTRSAGSA
0 1 S423 FPGPGERSLVGFGPP
0 1 S458 SLTGLVQSALLRGSE
0 2 T468-p LRGSEPEtPSEKIEG
0 1 S470 GSEPEtPSEKIEGSN
0 1 S476 PSEKIEGSNGAATPS
0 1 T481 EGSNGAATPSAPCGS
0 1 S483 SNGAATPSAPCGSGG
0 1 S493 CGSGGRSSGATPVSG
0 1 T496 GGRSSGATPVSGPPP
0 1 S499 SSGATPVSGPPPPSA
0 2 S505 VSGPPPPSASSTPAG
0 1 S508 PPPPSASSTPAGQPT
0 5 T509 PPPSASSTPAGQPTA
0 1 S518 AGQPTAVSRLQMQLH
0 1 S534-p RGLQNSAsDLRGQLQ
0 1 T585 DPLQRQRTLVEEERL
0 1 T602 LNDEELITQQLNDLE
0 1 K639 EEKALVLKQLGETLT
0 4 S716-p PNNLLSQsPKkVTAE
0 1 K719-m1 LLSQsPKkVTAETDF
0 1 S729-p AETDFNKsVDFEMPP
0 5 S738-p DFEMPPPsPPLNLHE
0 2 T756-p PAEGASLtPKGGNPT
0 2 S779 RSVDKAVSVEAAERD
0 2 S798-p RAALTQYsAKDINRL
0 1 K800 ALTQYsAKDINRLLE
0 1 T809-p INRLLEEtQAELLKA
1 25 S859-p EPSGRRGsDELTVPR
0 1 T869-p LTVPRYRtEKPSKsP
0 1 S873 RYRtEKPSKsPPPPP
1 5 S875-p RtEKPSKsPPPPPPR
0 1 S884 PPPPPRRSFPSSHGL
0 1 T894 SSHGLTTTRTGEVVV
0 1 K905-ac EVVVTSKkDSAFIKK
0 1 S907 VVTSKkDSAFIKKAE
0 6 S915-p AFIKKAEsEELEVQK
0 5 S932-p VKLRRAVsEVARPAS
0 2 S990-p AAQGQAGsPDKSKHG
0 3 S1027 SGSNETSSPVSEKPS
0 1 T1044-p RTSIPVLtSFGARNS
  SNIP iso5  
S6-p __MGNAPsQDPERss
S12-p PsQDPERssPPMLSA
S13-p sQDPERssPPMLSAD
S18 RssPPMLSADDAEYP
Y28-p DAEYPREyRTLGGGG
S45-p GSGGRRFsNVGLVHt
T52-p sNVGLVHtsERRHtV
S53-p NVGLVHtsERRHtVI
T58-p HtsERRHtVIAAQsL
S64-p HtVIAAQsLEALSGL
K88 DAFMDHLKsKYPQHA
S89-p AFMDHLKsKYPQHAL
K90 FMDHLKsKYPQHALA
Y91 MDHLKsKYPQHALAL
R99 PQHALALRGQQDRMR
Y111 RMREQPNYWSFKTRS
S113 REQPNYWSFKTRSSR
S118 YWSFKTRSSRHTQGA
K135 GLADQAAKLSYASAE
S137 ADQAAKLSYASAEsL
S140 AAKLSYASAEsLETM
S143-p LSYASAEsLETMSEA
S148 AEsLETMSEAELPLG
S165-p RMNRFRQsLPLsRSA
S169-p FRQsLPLsRSASQtK
T175-p LsRSASQtKLRSPGV
S179 ASQtKLRSPGVLFLQ
T219 HMFPQKLTMGMLKSP
S225 LTMGMLKSPNTAILI
T228 GMLKSPNTAILIKDE
K233 PNTAILIKDEARNVF
Y241 DEARNVFYELEDVRD
K256 IQDRSIIKIYRKEPL
Y258 DRSIIKIYRKEPLyA
Y264-p IYRKEPLyAAFPGSH
Y283 DLRREMVYASRESSP
S285 RREMVYASRESSPTR
S288 MVYASRESSPTRRLN
S289 VYASRESSPTRRLNN
S298 TRRLNNLSPAPHLAS
P301 LNNLSPAPHLASGSP
S305 SPAPHLASGSPPPGL
S307 APHLASGSPPPGLPS
S318 GLPSGLPSGLQSGSP
S322 GLPSGLQSGSPSRSR
S324 PSGLQSGSPSRSRLS
S326 GLQSGSPSRSRLSYA
S328 QSGSPSRSRLSYAGG
R329 SGSPSRSRLSYAGGR
S331 SPSRSRLSYAGGRPP
Y332 PSRSRLSYAGGRPPS
R336 RLSYAGGRPPSYAGS
S339 YAGGRPPSYAGSPVH
Y340 AGGRPPSYAGSPVHH
S343 RPPSYAGSPVHHAAE
A357 ERLGGAPAAQGVSPS
A358 RLGGAPAAQGVSPSP
S362 APAAQGVSPSPSAIL
S364 AAQGVSPSPSAILER
S366 QGVSPSPSAILERRD
K375 ILERRDVKPDEDLAS
K391 AGGMVLVKGEGLyAD
Y396-p LVKGEGLyADPYGLL
Y400 EGLyADPYGLLHEGR
S409 LLHEGRLSLAAAAGD
Y427 YPGAGGLYKRGSVRS
K428 PGAGGLYKRGSVRSL
K453 DLEDSLYKAAGGGGP
Y462 AGGGGPLYGDGYGFR
S474 GFRLPPSSPQKLADV
A482 PQKLADVAAPPGGPP
P485 LADVAAPPGGPPPPH
S493 GGPPPPHSPYSGPPS
Y495 PPPPHSPYSGPPSRG
S496 PPPHSPYSGPPSRGS
S500 SPYSGPPSRGSPVRQ
R501 PYSGPPSRGSPVRQS
S503 SGPPSRGSPVRQSFR
S508 RGSPVRQSFRKDSGS
S513 RQSFRKDSGSSSVFA
S515 SFRKDSGSSSVFAES
S516 FRKDSGSSSVFAESP
S517 RKDSGSSSVFAESPG
S522 SSSVFAESPGGKTRS
K526 FAESPGGKTRSAGSA
S551 FPGPGERSLVGFGPP
S586 SLTGLVQSALLRGSE
T596 LRGSEPETPSEKIEG
S598 GSEPETPSEKIEGSN
S604 PSEKIEGSNGAATPS
T609 EGSNGAATPSAPCGS
S611 SNGAATPSAPCGSGG
S621 CGSGGRSSGATPVSG
T624 GGRSSGATPVSGPPP
S627 SSGATPVSGPPPPSA
S633 VSGPPPPSASSTPAG
S636 PPPPSASSTPAGQPT
T637 PPPSASSTPAGQPTA
S646 AGQPTAVSRLQMQLH
S662 RGLQNSASDLRGQLQ
T713 DPLQRQRTLVEEERL
T730 LNDEELITQQLNDLE
K767 EEKALVLKQLGETLT
S844 PNNLLSQSPKKVTAE
K847 LLSQSPKKVTAETDF
S857 AETDFNKSVDFEMPP
S866 DFEMPPPSPPLNLHE
T884 PAEGASLTPKGGNPT
S907 RSVDKAVSVEAAERD
S926 RAALTQYSAKDINRL
K928 ALTQYSAKDINRLLE
T937 INRLLEETQAELLKA
S987-p EPSGRRGsDELTVPR
T997 LTVPRYRTEKPSKsP
S1001 RYRTEKPSKsPPPPP
S1003-p RTEKPSKsPPPPPPR
S1012 PPPPPRRSFPSSHGL
T1022 SSHGLTTTRTGEVVV
K1033 EVVVTSKKDSAFIKK
S1035 VVTSKKDSAFIKKAE
S1043 AFIKKAESEELEVQK
S1060 VKLRRAVSEVARPAS
S1118 AAQGQAGSPDKSKHG
S1155 SGSNETSSPVSEKPS
T1172 RTSIPVLTSFGARNS
  mouse

► Hide Isoforms
 
- gap
S46-p GEPDPERssPPMLsA
S47-p EPDPERssPPMLsAD
S52-p RssPPMLsADDAEYP
Y62 DAEYPREYRTLGGGG
S79-p GSGGRRFsNVGLVHt
T86-p sNVGLVHtsERRHtV
S87-p NVGLVHtsERRHtVI
T92-p HtsERRHtVIAAQsL
S98-p HtVIAAQsLEALSGL
K122 DAFMDHLKSkYPQHA
S123 AFMDHLKSkYPQHAL
K124-ub FMDHLKSkYPQHALA
Y125 MDHLKSkYPQHALAL
R133-m1 PQHALALrGQQDRMR
Y179 QPAQQPNYWSFKTRs
S181 AQQPNYWSFKTRsSR
S186-p YWSFKTRsSRHTQGA
K203-ac GLADQAAkLsYAsAE
S205-p ADQAAkLsYAsAEsL
S208-p AAkLsYAsAEsLETM
S211-p LsYAsAEsLETMsEA
S216-p AEsLETMsEAELPLG
S233-p RMNRFRQsLPLsRSA
S237-p FRQsLPLsRSASQTK
T243 LsRSASQTKLRsPGV
S247-p ASQTKLRsPGVLFLQ
T287-p HMFPQKLtMGMLKsP
S293-p LtMGMLKsPNtAILI
T296-p GMLKsPNtAILIKDE
K301 PNtAILIKDEARNVF
Y309-p DEARNVFyELEDVRD
K324 IQDRSIIKIYRKEPL
Y326 DRSIIKIYRKEPLyA
Y332-p IYRKEPLyAAFPGSH
Y351 DLRREMVYAsREssP
S353-p RREMVYAsREssPTR
S356-p MVYAsREssPTRRLN
S357-p VYAsREssPTRRLNN
S366-p TRRLNNLsPAsHLAs
S369-p LNNLsPAsHLAsSsP
S373-p sPAsHLAsSsPPPGL
S375-p AsHLAsSsPPPGLPS
S386-p GLPSGLPsGLPsGsP
S390-p GLPsGLPsGsPsRSr
S392-p PsGLPsGsPsRSrLs
S394-p GLPsGsPsRSrLsYA
S396 PsGsPsRSrLsYAGG
R397-m1 sGsPsRSrLsYAGGr
S399-p sPsRSrLsYAGGrPP
Y400 PsRSrLsYAGGrPPs
R404-m1 rLsYAGGrPPsyAGs
S407-p YAGGrPPsyAGsPVH
Y408-p AGGrPPsyAGsPVHH
S411-p rPPsyAGsPVHHAAE
T425-p ERLGGAPtGQGVsPs
G426 RLGGAPtGQGVsPsP
S430-p APtGQGVsPsPsAIL
S432-p tGQGVsPsPsAILER
S434-p QGVsPsPsAILERRD
K443 ILERRDVKPDEDLAG
K459 AGGMVLVKGEGLyAD
Y464-p LVKGEGLyADPyGLL
Y468-p EGLyADPyGLLHEGR
S477 LLHEGRLSLAAAAET
- gap
- gap
- gap
Y528 RRALAALYGDGYGFR
S540 GFRLPPSSPQKLADV
S548-gl PQKLADVsAPsGGPP
S551-p LADVsAPsGGPPPPH
S559-p GGPPPPHsPysGPPs
Y561-p PPPPHsPysGPPsrG
S562-p PPPHsPysGPPsrGs
S566-p sPysGPPsrGsPVRQ
R567-m1 PysGPPsrGsPVRQs
S569-p sGPPsrGsPVRQsFR
S574-p rGsPVRQsFRKDsGs
S579-p RQsFRKDsGsssVFA
S581-p sFRKDsGsssVFAEs
S582-p FRKDsGsssVFAEsP
S583-p RKDsGsssVFAEsPG
S588-p sssVFAEsPGGkARS
K592-ub FAEsPGGkARSTGSA
S617-p FPGPGERsLVGFGPP
S652-p SLTGLVQsALLRGSE
T662-p LRGSEPEtPsEKVEG
S664-p GSEPEtPsEKVEGsN
S670-p PsEKVEGsNGAAtPs
T675-p EGsNGAAtPsAPVCG
S677-p sNGAAtPsAPVCGSG
S688-p CGSGSKSsGAtPVsG
T691-p GSKSsGAtPVsGPPP
S694-p SsGAtPVsGPPPPsA
S700-p VsGPPPPsASstPAG
S703-p PPPPsASstPAGQPT
T704-p PPPsASstPAGQPTA
S713-p AGQPTAVsRLQMQLH
S729 RGLQNSASDLRGQLQ
T780-p DPLQRQRtLVEEERL
T797-p LNDEELItQQLNDLE
K834-ub EEKALVLkQLGETLT
S911-p PNNLLNQsPKKVAAE
K914 LLNQsPKKVAAETDF
G924 AETDFSKGLDFEIPP
S933-p DFEIPPPsPPLNLHE
T951-p PAEGTPLtPKSTNPT
S974-p RNTDKAVsVEAAERD
S993-p RAALTQYsAkDINRL
K995-ub ALTQYsAkDINRLLE
T1004 INRLLEETQAELLKA
S1054-p EPSGRRGsDELTVPR
T1064 LTVPRYRTEKPsKsP
S1068-p RYRTEKPsKsPPPPP
S1070-p RTEKPsKsPPPPPPR
S1079-p PPPPPRRsFPSSHGL
T1089-gl SSHGLTTtRTGEVVV
K1100 EVVVTSKKDsVFIKK
S1102-p VVTSKKDsVFIKKAE
S1110-p VFIKKAEsEELEVQK
S1127-p VKLRRAVsEVVRPAS
S1185-p AAQGPAGsPDKGKHG
S1222-p SGPNETSsPGSEKPS
T1239 RTSIPVLTSFGARNS
  SNIP iso4  
S6 __MGNAPSQDPERSS
S12 PSQDPERSSPPMLSA
S13 SQDPERSSPPMLSAD
S18 RSSPPMLSADDAEYP
Y28 DAEYPREYRTLGGGG
S45 GSGGRRFSNVGLVHT
T52 SNVGLVHTSERRHTV
S53 NVGLVHTSERRHTVI
T58 HTSERRHTVIAAQSL
S64 HTVIAAQSLEALSGL
K88 DAFMDHLKSKYPQHA
S89 AFMDHLKSKYPQHAL
K90 FMDHLKSKYPQHALA
Y91 MDHLKSKYPQHALAL
R99 PQHALALRGQQDRMR
Y145 QPAQQPNYWSFKTRS
S147 AQQPNYWSFKTRSSR
S152 YWSFKTRSSRHTQGA
K169 GLADQAAKLSYASAE
S171 ADQAAKLSYASAESL
S174 AAKLSYASAESLETM
S177 LSYASAESLETMSEA
S182 AESLETMSEAELPLG
S199 RMNRFRQSLPLSRSA
S203 FRQSLPLSRSASQTK
T209 LSRSASQTKLRSPGV
S213 ASQTKLRSPGVLFLQ
T253 HMFPQKLTMGMLKSP
S259 LTMGMLKSPNTAILI
T262 GMLKSPNTAILIKDE
K267 PNTAILIKDEARNVF
Y275 DEARNVFYELEDVRD
K290 IQDRSIIKIYRKEPL
Y292 DRSIIKIYRKEPLYA
Y298 IYRKEPLYAAFPGSH
Y317 DLRREMVYASRESSP
S319 RREMVYASRESSPTR
S322 MVYASRESSPTRRLN
S323 VYASRESSPTRRLNN
S332 TRRLNNLSPASHLAS
S335 LNNLSPASHLASSSP
S339 SPASHLASSSPPPGL
S341 ASHLASSSPPPGLPS
S352 GLPSGLPSGLPSGSP
S356 GLPSGLPSGSPSRSR
S358 PSGLPSGSPSRSRLS
S360 GLPSGSPSRSRLSYA
S362 PSGSPSRSRLSYAGG
R363 SGSPSRSRLSYAGGR
S365 SPSRSRLSYAGGRPP
Y366 PSRSRLSYAGGRPPS
R370 RLSYAGGRPPSYAGS
S373 YAGGRPPSYAGSPVH
Y374 AGGRPPSYAGSPVHH
S377 RPPSYAGSPVHHAAE
T391 ERLGGAPTGQGVSPS
G392 RLGGAPTGQGVSPSP
S396 APTGQGVSPSPSAIL
S398 TGQGVSPSPSAILER
S400 QGVSPSPSAILERRD
K409 ILERRDVKPDEDLAG
K425 AGGMVLVKGEGLYAD
Y430 LVKGEGLYADPYGLL
Y434 EGLYADPYGLLHEGR
S443 LLHEGRLSLAAAAGD
Y461 YPGAGGLYkRGSVRS
K462-ub PGAGGLYkRGSVRSL
K487 DLEDSLYKAGAGGPL
Y495 AGAGGPLYGDGYGFR
S507 GFRLPPSSPQKLADV
S515 PQKLADVSAPSGGPP
S518 LADVSAPSGGPPPPH
S526 GGPPPPHSPYSGPPS
Y528 PPPPHSPYSGPPSRG
S529 PPPHSPYSGPPSRGS
S533 SPYSGPPSRGSPVRQ
R534 PYSGPPSRGSPVRQS
S536 SGPPSRGSPVRQSFR
S541 RGSPVRQSFRKDSGS
S546 RQSFRKDSGSSSVFA
S548 SFRKDSGSSSVFAES
S549 FRKDSGSSSVFAESP
S550 RKDSGSSSVFAESPG
S555 SSSVFAESPGGKARS
K559 FAESPGGKARSTGSA
S584 FPGPGERSLVGFGPP
S619 SLTGLVQSALLRGSE
T629 LRGSEPETPSEKVEG
S631 GSEPETPSEKVEGSN
S637 PSEKVEGSNGAATPS
T642 EGSNGAATPSAPVCG
S644 SNGAATPSAPVCGSG
S655 CGSGSKSSGATPVSG
T658 GSKSSGATPVSGPPP
S661 SSGATPVSGPPPPSA
S667 VSGPPPPSASSTPAG
S670 PPPPSASSTPAGQPT
T671 PPPSASSTPAGQPTA
S680 AGQPTAVSRLQMQLH
S696 RGLQNSASDLRGQLQ
T747 DPLQRQRTLVEEERL
T764 LNDEELITQQLNDLE
K801 EEKALVLKQLGETLT
S878 PNNLLNQSPKKVAAE
K881 LLNQSPKKVAAETDF
G891 AETDFSKGLDFEIPP
S900 DFEIPPPSPPLNLHE
T918 PAEGTPLTPKSTNPT
S941 RNTDKAVSVEAAERD
S960 RAALTQYSAKDINRL
K962 ALTQYSAKDINRLLE
T971 INRLLEETQAELLKA
S1021 EPSGRRGSDELTVPR
T1031 LTVPRYRTEKPSKSP
S1035 RYRTEKPSKSPPPPP
S1037 RTEKPSKSPPPPPPR
S1046 PPPPPRRSFPSSHGL
T1056 SSHGLTTTRTGEVVV
K1067 EVVVTSKKDSVFIKK
S1069 VVTSKKDSVFIKKAE
S1077 VFIKKAESEELEVQK
S1094 VKLRRAVSEVVRPAS
S1152 AAQGPAGSPDKGKHG
S1189 SGPNETSSPGSEKPS
T1206 RTSIPVLTSFGARNS
  SNIP iso5  
- gap
S46 GEPDPERSSPPMLSA
S47 EPDPERSSPPMLSAD
S52 RSSPPMLSADDAEYP
Y62 DAEYPREYRTLGGGG
S79 GSGGRRFSNVGLVHT
T86 SNVGLVHTSERRHTV
S87 NVGLVHTSERRHTVI
T92 HTSERRHTVIAAQSL
S98 HTVIAAQSLEALSGL
K122 DAFMDHLKSKYPQHA
S123 AFMDHLKSKYPQHAL
K124 FMDHLKSKYPQHALA
Y125 MDHLKSKYPQHALAL
R133 PQHALALRGQQDRMR
Y146 MREQQPNYWsFKTRS
S148-p EQQPNYWsFKTRSSR
S153 YWsFKTRSSRHTQGA
K170 GLADQAAKLSYASAE
S172 ADQAAKLSYASAESL
S175 AAKLSYASAESLETM
S178 LSYASAESLETMSEA
S183 AESLETMSEAELPLG
S200 RMNRFRQSLPLSRSA
S204 FRQSLPLSRSASQTK
T210 LSRSASQTKLRSPGV
S214 ASQTKLRSPGVLFLQ
T254 HMFPQKLTMGMLKSP
S260 LTMGMLKSPNTAILI
T263 GMLKSPNTAILIKDE
K268 PNTAILIKDEARNVF
Y276 DEARNVFYELEDVRD
K291 IQDRSIIKIYRKEPL
Y293 DRSIIKIYRKEPLYA
Y299 IYRKEPLYAAFPGSH
Y318 DLRREMVYASRESSP
S320 RREMVYASRESSPTR
S323 MVYASRESSPTRRLN
S324 VYASRESSPTRRLNN
S333 TRRLNNLSPASHLAS
S336 LNNLSPASHLASSSP
S340 SPASHLASSSPPPGL
S342 ASHLASSSPPPGLPS
S353 GLPSGLPSGLPSGSP
S357 GLPSGLPSGSPSRSR
S359 PSGLPSGSPSRSRLS
S361 GLPSGSPSRSRLSYA
S363 PSGSPSRSRLSYAGG
R364 SGSPSRSRLSYAGGR
S366 SPSRSRLSYAGGRPP
Y367 PSRSRLSYAGGRPPS
R371 RLSYAGGRPPSYAGS
S374 YAGGRPPSYAGSPVH
Y375 AGGRPPSYAGSPVHH
S378 RPPSYAGSPVHHAAE
T392 ERLGGAPTGQGVSPS
G393 RLGGAPTGQGVSPSP
S397 APTGQGVSPSPSAIL
S399 TGQGVSPSPSAILER
S401 QGVSPSPSAILERRD
K410 ILERRDVKPDEDLAG
K426 AGGMVLVKGEGLYAD
Y431 LVKGEGLYADPYGLL
Y435 EGLYADPYGLLHEGR
S444 LLHEGRLSLAAAAGD
Y462 YPGAGGLYkRGSVRS
K463-ub PGAGGLYkRGSVRSL
K488 DLEDSLYKAGAGGPL
Y496 AGAGGPLYGDGYGFR
S508 GFRLPPSSPQKLADV
S516 PQKLADVSAPSGGPP
S519 LADVSAPSGGPPPPH
S527 GGPPPPHSPYSGPPS
Y529 PPPPHSPYSGPPSRG
S530 PPPHSPYSGPPSRGS
S534 SPYSGPPSRGSPVRQ
R535 PYSGPPSRGSPVRQS
S537 SGPPSRGSPVRQSFR
S542 RGSPVRQSFRKDSGS
S547 RQSFRKDSGSSSVFA
S549 SFRKDSGSSSVFAES
S550 FRKDSGSSSVFAESP
S551 RKDSGSSSVFAESPG
S556 SSSVFAESPGGKARS
K560 FAESPGGKARSTGSA
S585 FPGPGERSLVGFGPP
S620 SLTGLVQSALLRGSE
T630 LRGSEPETPSEKVEG
S632 GSEPETPSEKVEGSN
S638 PSEKVEGSNGAATPS
T643 EGSNGAATPSAPVCG
S645 SNGAATPSAPVCGSG
S656 CGSGSKSSGATPVSG
T659 GSKSSGATPVSGPPP
S662 SSGATPVSGPPPPSA
S668 VSGPPPPSASSTPAG
S671 PPPPSASSTPAGQPT
T672 PPPSASSTPAGQPTA
S681 AGQPTAVSRLQMQLH
S697 RGLQNSASDLRGQLQ
T748 DPLQRQRTLVEEERL
T765 LNDEELITQQLNDLE
K802 EEKALVLKQLGETLT
S879 PNNLLNQSPKKVAAE
K882 LLNQSPKKVAAETDF
G892 AETDFSKGLDFEIPP
S901 DFEIPPPSPPLNLHE
T919 PAEGTPLTPKSTNPT
S942 RNTDKAVSVEAAERD
S961 RAALTQYSAKDINRL
K963 ALTQYSAKDINRLLE
T972 INRLLEETQAELLKA
S1022 EPSGRRGSDELTVPR
T1032 LTVPRYRTEKPSKSP
S1036 RYRTEKPSKSPPPPP
S1038 RTEKPSKSPPPPPPR
S1047 PPPPPRRSFPSSHGL
T1057 SSHGLTTTRTGEVVV
K1068 EVVVTSKKDSVFIKK
S1070 VVTSKKDSVFIKKAE
S1078 VFIKKAESEELEVQK
S1095 VKLRRAVSEVVRPAS
S1153 AAQGPAGSPDKGKHG
- gap
- gap
  rat

 
- gap
S46-p GEPDPERssPPMLsA
S47-p EPDPERssPPMLsAD
S52-p RssPPMLsADDAEYP
Y62 DAEYPREYRTLGGGG
S79-p GSGGRRFsNVGLVHT
T86 sNVGLVHTSERRHTV
S87 NVGLVHTSERRHTVI
T92 HTSERRHTVIAAQSL
S98 HTVIAAQSLEALSGL
K122-ub DAFMDHLkSkyPQHA
S123 AFMDHLkSkyPQHAL
K124-ub FMDHLkSkyPQHALA
Y125-p MDHLkSkyPQHALAL
R133 PQHALALRGQQDRMR
Y146-p MREQQPNyWSFKTRS
S148 EQQPNyWSFKTRSSR
S153 yWSFKTRSSRHTQGA
K170 GLADQAAKLSYASAE
S172 ADQAAKLSYASAESL
S175 AAKLSYASAESLETM
S178 LSYASAESLETMSEA
S183 AESLETMSEAELPLG
S200-p RMNRFRQsLPLSRSA
S204 FRQsLPLSRSASQTK
T210 LSRSASQTKLRSPGV
S214 ASQTKLRSPGVLFLQ
T254 HMFPQKLTMGMLKSP
S260 LTMGMLKSPNTAILI
T263 GMLKSPNTAILIkDE
K268-ub PNTAILIkDEARNVF
Y276-p DEARNVFyELEDVRD
K291-ub IQDRSIIkIyRKEPL
Y293-p DRSIIkIyRKEPLyA
Y299-p IyRKEPLyAAFPGSH
Y318-p DLRREMVyAsRESSP
S320-p RREMVyAsRESSPTR
S323 MVyAsRESSPTRRLN
S324 VyAsRESSPTRRLNN
S333 TRRLNNLSPASHLAS
S336 LNNLSPASHLASSSP
S340 SPASHLASSSPPPGL
S342 ASHLASSSPPPGLPS
S353 GLPSGLPSGLPSGSP
S357 GLPSGLPSGSPSRSR
S359 PSGLPSGSPSRSRLS
S361 GLPSGSPSRSRLSyA
S363 PSGSPSRSRLSyAGG
R364 SGSPSRSRLSyAGGR
S366 SPSRSRLSyAGGRPP
Y367-p PSRSRLSyAGGRPPs
R371 RLSyAGGRPPsyAGs
S374-p yAGGRPPsyAGsPVH
Y375-p AGGRPPsyAGsPVHH
S378-p RPPsyAGsPVHHAAE
T392 ERLGGAPTsQGVsPS
S393-p RLGGAPTsQGVsPSP
S397-p APTsQGVsPSPSAIL
S399 TsQGVsPSPSAILER
S401 QGVsPSPSAILERRD
K410-ub ILERRDVkPDEDLAG
K426-ub AGGMVLVkGEGLyAD
Y431-p LVkGEGLyADPyGLL
Y435-p EGLyADPyGLLHEGR
S444 LLHEGRLSLAAAAGD
Y462-p YPGAGGLykRGSVRS
K463-ub PGAGGLykRGSVRSL
K488-ub DLEDSLYkAGAGGPL
Y496-p AGAGGPLyGDGYGFR
S508 GFRLPPSSPQKLADV
S516 PQKLADVSAPSGGPP
S519 LADVSAPSGGPPPPH
S527 GGPPPPHSPySGPPs
Y529-p PPPPHSPySGPPsRG
S530 PPPHSPySGPPsRGS
S534-p SPySGPPsRGSPVRQ
R535 PySGPPsRGSPVRQS
S537 SGPPsRGSPVRQSFR
S542 RGSPVRQSFRKDSGS
S547 RQSFRKDSGSSSVFA
S549 SFRKDSGSSSVFAES
S550 FRKDSGSSSVFAESP
S551 RKDSGSSSVFAESPG
S556 SSSVFAESPGGKARS
K560 FAESPGGKARSTGAS
S584 FPGPGERSLVGFGPP
S619 SLTGLVQSALLRGSE
T629 LRGSEPETPSEKIEG
S631 GSEPETPSEKIEGSN
S637 PSEKIEGSNGAATPS
T642 EGSNGAATPSAPVCG
S644 SNGAATPSAPVCGSG
S655 CGSGSRSSGATPVSG
T658 GSRSSGATPVSGPPP
S661 SSGATPVSGPPPPAV
A667 VSGPPPPAVSSTPAG
S670 PPPPAVSSTPAGQPT
T671 PPPAVSSTPAGQPTA
S680 AGQPTAVSRLQMQMH
S696 RGLQNSASDLRGQLQ
T747 DPLQRQRTLVEEERL
T764 LNDEELITQQLNDLE
K801 EEKALVLKQLGETLT
S878 PNNLLNQSPKKVAAE
K881 LLNQSPKKVAAETDF
G891 AETDFSKGLDFEIPP
S900 DFEIPPPSPPLNLHE
T918 PAEGTPLTPKSGNPT
S941 RNMDKAVSVEAAERD
S960 RAALTQYSAKDINRL
K962 ALTQYSAKDINRLLE
T971 INRLLEETQAELLKA
S1021-p EPSGRRGsDELTVPR
T1031 LTVPRYRTEKPSKSP
S1035 RYRTEKPSKSPPPPP
S1037 RTEKPSKSPPPPPPR
S1046 PPPPPRRSFPSSHGL
T1056 SSHGLTTTRTGEVVV
K1067 EVVVTSKKDSVFIKK
S1069 VVTSKKDSVFIKKAE
S1077 VFIKKAESEELEIQK
S1094 VKLRRAVSEVVRPAS
S1152 AAQGPAGSPDKGKHG
- gap
- gap
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