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Protein Page:
ERK2 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
ERK2 a serine/threonine kinase of the GMGC group that plays a critical role in the regulation of cell growth and differentiation. ERK1 (MAPK3) and ERK2 (MAPK1) play central roles in MAPK cascades and are activated by a wide variety of extracellular signals including growth and neurotrophic factors, cytokines, hormones and neurotransmitters. Depending on the cellular context, MAPK cascades mediate diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. MAPK cascades also plays a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. Activation of MAP kinases occurs through phosphorylation of threonine and tyrosine residues at the sequence T*EY* by upstream MAP kinase kinases, MEK1 and -2. Phosphorylation of both the threonine and tyrosine are required for activity. This phosphorylation causes dramatic conformational changes, which enable full activation and interaction of MAPK1/ERK2 with its substrates. Note: This description may include information from UniProtKB.
Protein type: Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.24; CMGC group; MAPK family; ERK subfamily; MAPK/ERK subfamily
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component: dendrite cytoplasm; Golgi apparatus; focal adhesion; protein complex; mitochondrion; early endosome; perikaryon; caveola; pseudopodium; cytosol; nucleoplasm; microtubule cytoskeleton; cytoskeleton; axon; cytoplasm; late endosome; microtubule organizing center; nucleus
Molecular Function: MAP kinase activity; RNA polymerase subunit kinase activity; protein serine/threonine kinase activity; protein binding; DNA binding; phosphotyrosine binding; mitogen-activated protein kinase kinase kinase binding; transcription factor binding; ATP binding; phosphatase binding
Biological Process: nerve growth factor receptor signaling pathway; viral reproduction; activation of MAPKK activity; activation of MAPK activity; positive regulation of transcription, DNA-dependent; response to toxin; stress-activated MAPK cascade; toll-like receptor 3 signaling pathway; sensory perception of pain; T cell receptor signaling pathway; protein amino acid phosphorylation; toll-like receptor 5 signaling pathway; B cell receptor signaling pathway; regulation of transcription factor activity; small GTPase mediated signal transduction; toll-like receptor 4 signaling pathway; platelet activation; fibroblast growth factor receptor signaling pathway; transcription, DNA-dependent; toll-like receptor 2 signaling pathway; regulation of stress-activated MAPK cascade; organ morphogenesis; nuclear translocation of MAPK; response to estrogen stimulus; toll-like receptor 9 signaling pathway; regulation of cytoskeleton organization and biogenesis; axon guidance; positive regulation of translation; apoptosis; regulation of protein stability; chemotaxis; signal transduction; toll-like receptor 10 signaling pathway; synaptic transmission; response to exogenous dsRNA; positive regulation of cell proliferation; lipopolysaccharide-mediated signaling pathway; response to stress; epidermal growth factor receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; MAPKKK cascade; peptidyl-threonine phosphorylation; mammary gland epithelial cell proliferation; cell cycle; MyD88-dependent toll-like receptor signaling pathway; peptidyl-serine phosphorylation; negative regulation of cell differentiation; cytosine metabolic process; Ras protein signal transduction; toll-like receptor signaling pathway; insulin receptor signaling pathway; innate immune response; vascular endothelial growth factor receptor signaling pathway; blood coagulation; response to DNA damage stimulus; positive regulation of cell migration
Reference #:  P28482 (UniProtKB)
Alt. Names/Synonyms: ERK; ERK-2; ERK2; ERT1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase-2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 1; MAPK 2; MAPK1; MAPK2; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; MK01; p40; p41; p41mapk; p42-MAPK; P42MAPK; PRKM1; PRKM2; protein tyrosine kinase ERK2
Gene Symbols: MAPK1
Molecular weight: 41,390 Da
Basal Isoelectric point: 6.5  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ERK2

Protein Structure Not Found.

Substrate Sequence Logo
Sequence Logo

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Sites Implicated In
cell differentiation, induced: T185‑p, Y187‑p
cell growth, altered: T185‑p, Y187‑p
cell growth, induced: T185‑p, Y187‑p
cell motility, altered: T185‑p, Y187‑p
cell motility, induced: T185‑p, Y187‑p
cytoskeletal reorganization: T185‑p, Y187‑p
transcription, inhibited: T185‑p, Y187‑p
activity, induced: T185‑p, Y187‑p
enzymatic activity, induced: S29‑p, T185‑p, Y187‑p, T190‑p
intracellular localization: T185‑p, Y187‑p, S246‑p, S248‑p
molecular association, regulation: S29‑p, T185‑p, Y187‑p, T190‑p, S246‑p, S248‑p
phosphorylation: T185‑p, Y187‑p
protein conformation: T185‑p, Y187‑p, T190‑p
protein degradation: T185‑p, Y187‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 Y25-p VFDVGPRyTNLsYIG
1 0 S29-p GPRyTNLsYIGEGAy
0 1 Y30 PRyTNLsYIGEGAyG
0 3 Y36-p sYIGEGAyGMVCSAy
0 7 Y43-p yGMVCSAyDNVNKVR
0 1 K55-ub KVRVAIKkISPFEHQ
0 1 K99-ub APTIEQMkDVYIVQD
0 3 Y113-p DLMETDLyKLLKTQH
0 1 K151 NVLHRDLKPSNLLLN
4 42 T181-p ADPDHDHtGFLtEyV
1036 2467 T185-p HDHtGFLtEyVAtRW
1057 4062 Y187-p HtGFLtEyVAtRWyR
1 28 T190-p FLtEyVAtRWyRAPE
0 4 Y193-p EyVAtRWyRAPEIML
0 3 K203-ub PEIMLNSkGytKSID
1 1 Y205-p IMLNSkGytKSIDIW
1 1 T206-p MLNSkGytKSIDIWS
2 1 S246-p HILGILGsPsQEDLN
2 0 S248-p LGILGsPsQEDLNCI
0 1 K259 LNCIINLKARNyLLS
0 1 Y263-p INLKARNyLLSLPHK
0 1 S284-p RLFPNADsKALDLLD
0 1 K285 LFPNADsKALDLLDk
0 1 K292 KALDLLDKMLTFNPH
0 1 K292-ub KALDLLDkMLTFNPH
0 2 K344-ub DLPKEKLkELIFEET
0 2 S360-p RFQPGYRs_______
3510 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4094 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Biotinylated)
4284 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4344 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4370 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb
4374 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 488 Conjugate)
4375 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 647 Conjugate)
4376 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb
4377 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb
5682 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (PE Conjugate)
5726 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb
8544 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (HRP Conjugate)
9101 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody
9106 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb
9488 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
12638 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Pacific Blue(TM) Conjugate)
13148 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
13214 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
14095 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (PE Conjugate)
14196 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Pacific Blue(TM) Conjugate)
14227 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Biotinylated)
14474 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (HRP Conjugate)
75165 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb (PE Conjugate)
3510 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4094 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Biotinylated)
4284 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4344 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4370 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb
4374 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 488 Conjugate)
4375 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 647 Conjugate)
4376 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb
4377 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb
5682 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (PE Conjugate)
5726 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb
8544 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (HRP Conjugate)
9101 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody
9106 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb
9488 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
12638 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Pacific Blue(TM) Conjugate)
13148 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
13214 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
14095 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (PE Conjugate)
14196 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Pacific Blue(TM) Conjugate)
14227 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Biotinylated)
14474 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (HRP Conjugate)
75165 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb (PE Conjugate)
  mouse

 
Y23 VFDVGPRYTNLSYIG
S27 GPRYTNLSYIGEGAY
Y28 PRYTNLSYIGEGAYG
Y34 SYIGEGAYGMVCSAY
Y41 YGMVCSAYDNLNKVR
K53 KVRVAIKKISPFEHQ
K97 APTIEQMKDVYIVQD
Y111 DLMETDLYKLLKTQH
K149-ub NVLHRDLkPSNLLLN
T179-p ADPDHDHtGFLtEyV
T183-p HDHtGFLtEyVAtRW
Y185-p HtGFLtEyVAtRWYR
T188-p FLtEyVAtRWYRAPE
Y191 EyVAtRWYRAPEIML
K201-ub PEIMLNSkGYTKSID
Y203 IMLNSkGYTKSIDIW
T204 MLNSkGYTKSIDIWS
S244 HILGILGSPSQEDLN
S246 LGILGSPSQEDLNCI
K257-ub LNCIINLkARNYLLS
Y261 INLkARNYLLSLPHK
S282 RLFPNADSKALDLLD
K283 LFPNADSKALDLLDK
K290 KALDLLDKMLTFNPH
K290 KALDLLDKMLTFNPH
K342 DLPKEKLKELIFEET
S358 RFQPGYRS_______
3510 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4094 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Biotinylated)
4284 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4344 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4370 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb
4374 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 488 Conjugate)
4375 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 647 Conjugate)
4376 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb
4377 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb
5682 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (PE Conjugate)
5726 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb
8544 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (HRP Conjugate)
9101 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody
9106 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb
9488 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
12638 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Pacific Blue(TM) Conjugate)
13148 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
13214 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
14095 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (PE Conjugate)
14196 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Pacific Blue(TM) Conjugate)
14227 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Biotinylated)
14474 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (HRP Conjugate)
75165 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb (PE Conjugate)
3510 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4094 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Biotinylated)
4284 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4344 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4370 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb
4374 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 488 Conjugate)
4375 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 647 Conjugate)
4376 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb
4377 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb
5682 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (PE Conjugate)
5726 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb
8544 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (HRP Conjugate)
9101 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody
9106 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb
9488 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
12638 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Pacific Blue(TM) Conjugate)
13148 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
13214 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
14095 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (PE Conjugate)
14196 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Pacific Blue(TM) Conjugate)
14227 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Biotinylated)
14474 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (HRP Conjugate)
75165 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb (PE Conjugate)
  rat

 
Y23 VFDVGPRYTNLsyIG
S27-p GPRYTNLsyIGEGAY
Y28-p PRYTNLsyIGEGAYG
Y34 syIGEGAYGMVCSAy
Y41-p YGMVCSAyDNLNKVR
K53 KVRVAIKKISPFEHQ
K97 APTIEQMKDVYIVQD
Y111 DLMETDLYKLLKTQH
K149 NVLHRDLKPSNLLLN
T179-p ADPDHDHtGFLtEyV
T183-p HDHtGFLtEyVAtRW
Y185-p HtGFLtEyVAtRWYR
T188-p FLtEyVAtRWYRAPE
Y191 EyVAtRWYRAPEIML
K201 PEIMLNSKGytKSID
Y203-p IMLNSKGytKSIDIW
T204-p MLNSKGytKSIDIWS
S244 HILGILGSPSQEDLN
S246 LGILGSPSQEDLNCI
K257 LNCIINLKARNYLLS
Y261 INLKARNYLLSLPHK
S282 RLFPNADSkALDLLD
K283-ac LFPNADSkALDLLDk
K290-ac kALDLLDkMLTFNPH
K290 kALDLLDKMLTFNPH
K342 DLPKEKLKELIFEET
S358 RFQPGYRS_______
3510 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4094 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Biotinylated)
4284 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4344 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4370 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb
4374 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 488 Conjugate)
4375 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 647 Conjugate)
4376 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb
4377 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb
5682 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (PE Conjugate)
5726 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb
8544 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (HRP Conjugate)
9101 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody
9106 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb
9488 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
12638 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Pacific Blue(TM) Conjugate)
13148 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
13214 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
14095 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (PE Conjugate)
14196 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Pacific Blue(TM) Conjugate)
14227 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Biotinylated)
14474 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (HRP Conjugate)
75165 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb (PE Conjugate)
3510 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4094 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Biotinylated)
4284 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4344 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4370 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb
4374 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 488 Conjugate)
4375 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 647 Conjugate)
4376 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb
4377 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb
5682 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (PE Conjugate)
5726 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb
8544 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (HRP Conjugate)
9101 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody
9106 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb
9488 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
12638 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Pacific Blue(TM) Conjugate)
13148 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
13214 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
14095 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (PE Conjugate)
14196 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Pacific Blue(TM) Conjugate)
14227 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Biotinylated)
14474 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (HRP Conjugate)
75165 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb (PE Conjugate)
  chicken

 
Y33 VFDVGPRYTNLSYIG
S37 GPRYTNLSYIGEGAY
Y38 PRYTNLSYIGEGAYG
Y44 SYIGEGAYGMVCSAY
Y51 YGMVCSAYDNVNKVR
K63 KVRVAIKKISPFEHQ
K107 APTIEQMKDVYIVQD
Y121 DLMETDLYKLLKTQH
K159 NVLHRDLKPSNLLLN
T189 ADPDHDHTGFLTEYV
T193 HDHTGFLTEYVATRW
Y195 HTGFLTEYVATRWYR
T198 FLTEYVATRWYRAPE
Y201 EYVATRWYRAPEIML
K211 PEIMLNSKGYTKSID
Y213 IMLNSKGYTKSIDIW
T214 MLNSKGYTKSIDIWS
S254 HILGILGSPSQEDLN
S256 LGILGSPSQEDLNCI
K267 LNCIINLKARNYLLS
Y271 INLKARNYLLSLPHK
P292 RLFPNADPKALDLLD
K293 LFPNADPKALDLLDK
K300 KALDLLDKMLTFNPH
K300 KALDLLDKMLTFNPH
K352 DLPKEKLKELIFEET
S368 RFQPGYRS_______
3510 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4094 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Biotinylated)
4284 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4344 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4370 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb
4374 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 488 Conjugate)
4375 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 647 Conjugate)
4376 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb
4377 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb
5682 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (PE Conjugate)
5726 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb
8544 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (HRP Conjugate)
9101 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody
9106 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb
9488 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
12638 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Pacific Blue(TM) Conjugate)
13148 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
13214 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
14095 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (PE Conjugate)
14196 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Pacific Blue(TM) Conjugate)
14227 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Biotinylated)
14474 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (HRP Conjugate)
75165 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb (PE Conjugate)
3510 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Sepharose Bead Conjugate)
4094 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Biotinylated)
4284 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
4344 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
4370 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb
4374 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 488 Conjugate)
4375 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb (Alexa Fluor(R) 647 Conjugate)
4376 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb
4377 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb
5682 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (PE Conjugate)
5726 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb
8544 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (HRP Conjugate)
9101 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody
9106 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (E10) Mouse mAb
9488 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Magnetic Bead Conjugate)
12638 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP(R) Rabbit mAb (Pacific Blue(TM) Conjugate)
13148 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 647 Conjugate)
13214 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Alexa Fluor(R) 488 Conjugate)
14095 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (PE Conjugate)
14196 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Pacific Blue(TM) Conjugate)
14227 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (Biotinylated)
14474 : Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (197G2) Rabbit mAb (HRP Conjugate)
75165 : Phospho-p44/42 MAPK (Erk1) (Tyr204)/(Erk2) (Tyr187) (D1H6G) Mouse mAb (PE Conjugate)
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