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Protein Page:
ArgBP2 (mouse)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
ArgBP2 Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. 7 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold
Cellular Component: cytoskeleton; cell soma; cytoplasm; dendrite; postsynaptic density; plasma membrane; cell junction
Molecular Function: protein domain specific binding; metal ion binding
Biological Process: cell migration; actin filament organization; cell adhesion
Reference #:  Q3UTJ2-2 (UniProtKB)
Alt. Names/Synonyms: 2010203O03Rik; 9430041O17Rik; A530071H08; Arg/Abl-interacting protein 2; Arg/Abl-interacting protein ArgBP2; ArgBP2; Kiaa0777; mKIAA0777; sorbin and SH3 domain containing 2; Sorbin and SH3 domain-containing protein 2; Sorbs2; SRBS2
Gene Symbols: Sorbs2
Molecular weight: 145,012 Da
Basal Isoelectric point: 8.51  Predict pI for various phosphorylation states
Select Structure to View Below

ArgBP2

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       mouse

► Hide Isoforms
 
0 70 S27-p TSVKRVQssPNLLAA
0 7 S28-p SVKRVQssPNLLAAG
0 5 S40-p AAGRESQsPDSAWRS
0 10 S43 RESQsPDSAWRSYND
0 5 Y62 TLNGDATYSSLAAKG
0 2 - gap
0 1 K68 TYSSLAAKGFRSVRP
1 0 Y104 AVSPVSYYQRPFsPS
0 2 S109-p SYYQRPFsPSAYSLP
1 0 Y113 RPFsPSAYSLPASLN
0 1 S130-p IIMQHGRsLDSAEtY
0 1 T136-p RsLDSAEtYsQHAQs
0 3 S138-p LDSAEtYsQHAQsLD
0 8 S143-p tYsQHAQsLDGTMGS
0 6 Y172 TVIKAPHYPGIGPVD
1 3 Y218 PDEDTDMYNTPYTYN
0 2 T220 EDTDMYNTPYTYNAG
1 0 Y229 YTYNAGLYNSPYSAQ
0 27 Y246 PAAKTQTYRPLsKsH
0 2 S250-p TQTYRPLsKsHsDNG
0 1 S252-p TYRPLsKsHsDNGTD
0 9 S254-p RPLsKsHsDNGTDAF
0 5 G257 sKsHsDNGTDAFKEV
0 3 S266-p DAFKEVPsPVPPPHV
0 1 S282-p PRPRDQSstLKHDWD
0 3 T283-p RPRDQSstLKHDWDP
0 1 S302 VDTRKFRSEPRsIFE
0 2 S306-p KFRSEPRsIFEYEPG
0 1 S343-p EPSRKPLsVsPstDG
0 5 S345-p SRKPLsVsPstDGLR
0 3 S347-p KPLsVsPstDGLRsP
0 1 T348-p PLsVsPstDGLRsPs
0 12 S353-p PstDGLRsPsPPPRS
0 18 S355-p tDGLRsPsPPPRSCV
0 2 S368-p CVPAPRPsAPDLsPT
0 11 S373-p RPsAPDLsPTRTGRI
0 1 Y412-p PPKKALDyVQDHsSG
0 2 S417-p LDyVQDHsSGVsNEV
0 1 S421-p QDHsSGVsNEVSIYQ
0 6 S425 SGVsNEVSIYQSSID
0 23 Y427 VsNEVSIYQSSIDRs
0 1 S430 EVSIYQSSIDRsLER
0 5 S434-p YQSSIDRsLERPsss
0 2 S439-p DRsLERPsssAsMAG
0 3 S440-p RsLERPsssAsMAGD
0 3 S441-p sLERPsssAsMAGDF
0 3 S443-p ERPsssAsMAGDFRK
0 33 S454-p DFRKRRKsEPAVGPL
0 1 S468-p LRGLGDQsSSRtsPG
0 5 T472-p GDQsSSRtsPGRADL
0 4 S473-p DQsSSRtsPGRADLP
0 1 S482-p GRADLPGsSSTFTkS
0 1 K488-u GsSSTFTkSFIsssP
0 1 S492-p TFTkSFIsssPssPs
0 16 S493-p FTkSFIsssPssPsR
0 9 S494-p TkSFIsssPssPsRA
0 8 S496-p SFIsssPssPsRAQG
0 21 S497-p FIsssPssPsRAQGG
0 5 S499-p sssPssPsRAQGGDD
0 1 T566-p NAEIWSStEETVsPK
0 2 S571-p SStEETVsPKIKSRs
0 2 S578-p sPKIKSRsCDDLLND
0 2 S589-p LLNDDCDsFPDPKTK
0 1 S599-p DPKTKSEsMGsLLCE
0 1 S602-p TKSEsMGsLLCEEDS
0 2 S689-p RGLLHGWsQsstEEV
0 1 S691-p LLHGWsQsstEEVPR
0 3 S692-p LHGWsQsstEEVPRD
0 1 T693-p HGWsQsstEEVPRDV
0 1 S717-p KLIQKSKsMPNLGDE
0 2 S727-p NLGDEMLsPITLEPP
0 9 S745-p LCPKRRFsIEsLLEE
0 8 S748-p KRRFsIEsLLEEETQ
0 2 - gap
0 1 S896-p SKLAFLVsPVPFRRK
0 3 T907-p FRRKKILtPQKQTEK
0 2 K910 KKILtPQKQTEKAKC
0 1 K918-u QTEKAKCkAsVVEAL
0 2 S920-p EKAKCkAsVVEALDS
0 10 S944-p KAEKRRGsLPDNSIL
0 4 K973 NSSLHALKRSPMHQP
0 3 S1007-p GRMPHSAsFPDVDTT
0 2 S1033 LSLQDHESPRsYsst
0 1 S1036-p QDHESPRsYsstLtD
0 1 S1036-gl QDHESPRsYsstLtD
0 2 S1038-p HESPRsYsstLtDLG
0 2 S1039-p ESPRsYsstLtDLGR
0 2 T1040-p SPRsYsstLtDLGRs
0 1 T1042-p RsYsstLtDLGRsAS
0 1 S1047-gl tLtDLGRsASRERRG
0 6 K1070 AKAVYDFKAQtSKEL
0 1 T1073-p VYDFKAQtSKELSFK
0 1 T1084 LSFKKGDTVYILRKI
0 3 Y1086 FKKGDTVYILRKIDQ
0 3 Y1111 VGIFPISYVEKLTPP
0 3 T1116 ISYVEKLTPPEKAQP
1 1 Y1202 NAKGAEDYPDPPLPH
0 2 S1210-p PDPPLPHsYssDRIY
0 6 S1212-p PPLPHsYssDRIYTL
0 2 S1213-p PLPHsYssDRIYTLS
0 7 T1286-p RRTKFFGtFPGNYVk
0 1 K1293-u tFPGNYVkRL_____
  ArgBP2 iso1  
S27 TSVKRVQSSPNLLAA
S28 SVKRVQSSPNLLAAG
S40 AAGRESQSPDSAWRS
S43 RESQSPDSAWRSYND
Y62 TLNGDATYSSLAAKG
- gap
K68 TYSSLAAKGFRSVRP
Y104 AVSPVSYYQRPFSPS
S109 SYYQRPFSPSAYSLP
Y113 RPFSPSAYSLPASLN
S130 IIMQHGRSLDSAETY
T136 RSLDSAETYSQHAQS
S138 LDSAETYSQHAQSLD
S143 TYSQHAQSLDGTMGS
Y172 TVIKAPHYPGIGPVD
- gap
- gap
Y214 MVHKPGLYNSPYSAQ
Y231 PAAKTQTYRPLSKSH
S235 TQTYRPLSKSHSDNG
S237 TYRPLSKSHSDNGTD
S239 RPLSKSHSDNGTDAF
G242 SKSHSDNGTDAFKEV
S251 DAFKEVPSPVPPPHV
S267 PRPRDQSSTLKHDWD
T268 RPRDQSSTLKHDWDP
S287 VDTRKFRSEPRSIFE
S291 KFRSEPRSIFEYEPG
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S310 LQHERPVSIyQSSID
Y312-p HERPVSIyQSSIDRS
S315 PVSIyQSSIDRSLER
S319 yQSSIDRSLERPSSS
S324 DRSLERPSSSASMAG
S325 RSLERPSSSASMAGD
S326 SLERPSSSASMAGDF
S328 ERPSSSASMAGDFRK
S339 DFRKRRKSEPAVGPL
S353 LRGLGDQSSSRTSPG
T357 GDQSSSRTSPGRADL
S358 DQSSSRTSPGRADLP
S367 GRADLPGSSSTFTKS
K373 GSSSTFTKSFISSSP
S377 TFTKSFISSSPSSPS
S378 FTKSFISSSPSSPSR
S379 TKSFISSSPSSPSRA
S381 SFISSSPSSPSRAQG
S382 FISSSPSSPSRAQGG
S384 SSSPSSPSRAQGGDD
T451 NAEIWSSTEETVSPK
S456 SSTEETVSPKIKSRS
S463 SPKIKSRSCDDLLND
S474 LLNDDCDSFPDPKTK
S484 DPKTKSESMGSLLCE
S487 TKSESMGSLLCEEDS
S574 RGLLHGWSQSSTEEV
S576 LLHGWSQSSTEEVPR
S577 LHGWSQSSTEEVPRD
T578 HGWSQSSTEEVPRDV
S602 KLIQKSKSMPNLGDE
S612 NLGDEMLSPITLEPP
S630 LCPKRRFSIESLLEE
S633 KRRFSIESLLEEETQ
K752 TRFTTMLKHERAKHE
S781 SKLAFLVSPVPFRRK
T792 FRRKKILTPQKQTEK
K795 KKILTPQKQTEKAKC
K803 QTEKAKCKASVVEAL
S805 EKAKCKASVVEALDS
S829 KAEKRRGSLPDNSIL
K858 NSSLHALKRSPMHQP
S892 GRMPHSASFPDVDTT
S918 LSLQDHESPRSYSST
S921 QDHESPRSYSSTLTD
S921 QDHESPRSYSSTLTD
S923 HESPRSYSSTLTDLG
S924 ESPRSYSSTLTDLGR
T925 SPRSYSSTLTDLGRS
T927 RSYSSTLTDLGRSAS
S932 TLTDLGRSASRERRG
K955 AKAVYDFKAQTSKEL
T958 VYDFKAQTSKELSFK
T969 LSFKKGDTVYILRKI
Y971 FKKGDTVYILRKIDQ
Y996 VGIFPISYVEKLTPP
T1001 ISYVEKLTPPEKAQP
Y1087 NAKGAEDYPDPPLPH
S1095 PDPPLPHSYSSDRIY
S1097 PPLPHSYSSDRIYTL
S1098 PLPHSYSSDRIYTLS
T1171 RRTKFFGTFPGNYVK
K1178 TFPGNYVKRL_____
  ArgBP2 iso5  
S27-p TSVKRVQsSPNLLAA
S28 SVKRVQsSPNLLAAG
S40-p AAGRESQsPDsAkGF
S43-p RESQsPDsAkGFRSV
- gap
- gap
K45-u SQsPDsAkGFRSVRP
Y81 AVSPVSYYQRPFSPS
S86 SYYQRPFSPSAYSLP
Y90 RPFSPSAYSLPASLN
S107 IIMQHGRSLDSAETY
T113 RSLDSAETYSQHAQS
S115 LDSAETYSQHAQSLD
S120 TYSQHAQSLDGTMGS
Y149 TVIKAPHYPGIGPVD
Y195 PDEDTDMYNTPYTYN
T197 EDTDMYNTPYTYNAG
Y206 YTYNAGLYNSPYSAQ
Y223 PAAKTQTYRPLSKSH
S227 TQTYRPLSKSHSDNG
S229 TYRPLSKSHSDNGTD
S231 RPLSKSHSDNGTDAF
G234 SKSHSDNGTDAFKEV
S243 DAFKEVPSPVPPPHV
S259 PRPRDQSSTLKHDWD
T260 RPRDQSSTLKHDWDP
S279 VDTRKFRSEPRSIFE
S283 KFRSEPRSIFEYEPG
S320 EPSRKPLSVSPSTDG
S322 SRKPLSVSPSTDGLR
S324 KPLSVSPSTDGLRSP
T325 PLSVSPSTDGLRSPS
S330 PSTDGLRSPSPPPRS
S332 TDGLRSPSPPPRSCV
S345 CVPAPCPSAPDLSPT
S350 CPSAPDLSPTRPPKK
Y361 PPKKALDYVQDHSSG
S366 LDYVQDHSSGVSNEV
S370 QDHSSGVSNEVSIYQ
S374 SGVSNEVSIYQSSID
Y376 VSNEVSIYQSSIDRS
S379 EVSIYQSSIDRSLER
S383 YQSSIDRSLERPSSS
S388 DRSLERPSSSASMAG
S389 RSLERPSSSASMAGD
S390 SLERPSSSASMAGDF
S392 ERPSSSASMAGDFRK
S403 DFRKRRKSEPAVGPL
S417 LRGLGDQSSSRTSPG
T421 GDQSSSRTSPGRADL
S422 DQSSSRTSPGRADLP
S431 GRADLPGSSSTFTKS
K437 GSSSTFTKSFISsSP
S441 TFTKSFISsSPSsPS
S442-p FTKSFISsSPSsPSR
S443 TKSFISsSPSsPSRA
S445 SFISsSPSsPSRAQD
S446-p FISsSPSsPSRAQDH
S448 SsSPSsPSRAQDHEs
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S455-p SRAQDHEsPRSYSST
S458 QDHEsPRSYSSTLTD
S458 QDHEsPRSYSSTLTD
S460 HEsPRSYSSTLTDLG
S461 EsPRSYSSTLTDLGR
T462 sPRSYSSTLTDLGRS
T464 RSYSSTLTDLGRSAS
S469 TLTDLGRSASRERRG
K492 AKAVYDFKAQTSKEL
T495 VYDFKAQTSKELSFK
T506 LSFKKGDTVYILRKI
Y508 FKKGDTVYILRKIDQ
Y533 VGIFPISYVEKLTPP
T538 ISYVEKLTPPEKAQP
Y624 NAKGAEDYPDPPLPH
S632 PDPPLPHSYSSDRIY
S634 PPLPHSYSSDRIYTL
S635 PLPHSYSSDRIYTLS
T698 RRTKFFGTFPGNYVK
K705 TFPGNYVKRL_____
  human

► Hide Isoforms
 
- gap
- gap
- gap
- gap
- gap
- gap
- gap
Y4 ____MSYYQRPFSPS
S9 SYYQRPFSPSAYSLP
Y13 RPFSPSAYSLPASLN
S30 IVMQHGTSLDSTDTY
T36 TSLDSTDTYPQHAQS
P38 LDSTDTYPQHAQSLD
S43 TYPQHAQSLDGTTSS
Y72-p TVIKAPHyPGIGPVD
Y118-p PDDDTDMyNtPYTYN
T120-p DDTDMyNtPYTYNAG
Y129 YTYNAGLYNPPYSAQ
Y146-p PAAKTQTyRPLsKSH
S150-p TQTyRPLsKSHsDNs
S152 TyRPLsKSHsDNsPN
S154-p RPLsKSHsDNsPNAF
S157-p sKSHsDNsPNAFKDA
S166-p NAFKDASsPVPPPHV
S187-p LRPRDRSstEKHDWD
T188-p RPRDRSstEKHDWDP
S207-p VDTRKFRsEPRSIFE
S211 KFRsEPRSIFEYEPG
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S230-p LQHERPAsLyQSsID
Y232-p HERPAsLyQSsIDRs
S235-p PAsLyQSsIDRsLER
S239-p yQSsIDRsLERPMsS
M244 DRsLERPMsSAsMAS
S245-p RsLERPMsSAsMASD
S246 sLERPMsSAsMASDF
S248-p ERPMsSAsMASDFRK
S259-p DFRKRRKsEPAVGPP
S273-p PRGLGDQsASRtsPG
T277-p GDQsASRtsPGRVDL
S278-p DQsASRtsPGRVDLP
S287-p GRVDLPGsSTTLTKS
K293 GsSTTLTKSFTSssP
S297 TLTKSFTSssPssPs
S298-p LTKSFTSssPssPsR
S299-p TKSFTSssPssPsRA
S301-p SFTSssPssPsRAKG
S302-p FTSssPssPsRAKGG
S304-p SssPssPsRAKGGDD
T371 NAEIWSSTEETVSPK
S376 SSTEETVSPKIKSRS
S383 SPKIKSRSCDDLLND
S394 LLNDDCDSFPDPKVK
S404 DPKVKSESMGSLLCE
S407 VKSESMGSLLCEEDS
S494 KDLLRAWSQCSTEEV
C496 LLRAWSQCSTEEVPR
S497 LRAWSQCSTEEVPRD
T498 RAWSQCSTEEVPRDM
S522 KLIQKSKSMPNLGDD
S532 NLGDDMLSPVTLEPP
S550-p LCPKRRFsIEYLLEE
Y553 KRRFsIEYLLEEENQ
K673 TRFTTMLKHERARHE
S702 SKLAFLVSPVPFRRK
A713 FRRKKNSAPKKQTEK
K716 KKNSAPKKQTEKAKC
K724 QTEKAKCKASVFEAL
S726 EKAKCKASVFEALDS
S750-p KAEKKRGsLPDNSIL
R779 NSSLRALRRSPLHQP
S813 GRMPRSASFQDVDTA
S838-p GALQDREsPRSYSST
S841 QDREsPRSYSSTLTD
S841 QDREsPRSYSSTLTD
S843 REsPRSYSSTLTDMG
S844 EsPRSYSSTLTDMGR
T845 sPRSYSSTLTDMGRS
T847 RSYSSTLTDMGRSAP
S852 TLTDMGRSAPRERRG
K875-a AKAVYDFkAQTSKEL
T878 VYDFkAQTSKELSFK
T889-p LSFKKGDtVyILRKI
Y891-p FKKGDtVyILRKIDQ
Y916-p VGIFPISyVEKLtPP
T921-p ISyVEKLtPPEKAQP
Y1007-p NTKGAEDyPDPPIPH
S1015-p PDPPIPHsYssDRIH
S1017-p PPIPHsYssDRIHSL
S1018-p PIPHsYssDRIHSLS
T1091-p RRTKFFGtFPGNYVK
K1098 tFPGNYVKRL_____
  ArgBP2 iso2  
- gap
- gap
S9 NTGRDSQSPDsAKGF
S12-p RDSQSPDsAKGFRSV
- gap
- gap
K14 SQSPDsAKGFRSVRP
Y50-p AVSPMSYyQRPFSPS
S55 SYyQRPFSPSAySLP
Y59-p RPFSPSAySLPASLN
S76 IVMQHGTSLDSTDTY
T82 TSLDSTDTYPQHAQS
P84 LDSTDTYPQHAQSLD
S89 TYPQHAQSLDGTTSS
Y118 TVIKAPHYPGIGPVD
Y164-p PDDDTDMyNTPYTYN
T166 DDTDMyNTPYTYNAG
Y175-p YTYNAGLyNPPYSAQ
Y192 PAAKTQTYRPLSKSH
S196 TQTYRPLSKSHSDNS
S198 TYRPLSKSHSDNSPN
S200 RPLSKSHSDNSPNAF
S203 SKSHSDNSPNAFKDA
S212 NAFKDASSPVPPPHV
S233 LRPRDRSSTEKHDWD
T234 RPRDRSSTEKHDWDP
S253 VDTRKFRSEPRSIFE
S257 KFRSEPRSIFEYEPG
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
Y310 PPKKPLDYVQDHSSG
S315 LDYVQDHSSGVFNEA
F319 QDHSSGVFNEAsLyQ
S323-p SGVFNEAsLyQSSID
Y325-p VFNEAsLyQSSIDRS
S328 EAsLyQSSIDRSLER
S332 yQSSIDRSLERPMSs
M337 DRSLERPMSsASMAS
S338 RSLERPMSsASMASD
S339-p SLERPMSsASMASDF
S341 ERPMSsASMASDFRK
S352-p DFRKRRKsEPAVGPP
S366 PRGLGDQSASRTSPG
T370 GDQSASRTSPGRVDL
S371 DQSASRTSPGRVDLP
S380 GRVDLPGSSTTLTKS
K386 GSSTTLTKSFTSSSP
S390 TLTKSFTSSSPSsPs
S391 LTKSFTSSSPSsPsR
S392 TKSFTSSSPSsPsRA
S394 SFTSSSPSsPsRAKD
S395-p FTSSSPSsPsRAKDR
S397-p SSSPSsPsRAKDREs
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S404-p sRAKDREsPRSYSST
S407 KDREsPRSYSSTLTD
S407 KDREsPRSYSSTLTD
S409 REsPRSYSSTLTDMG
S410 EsPRSYSSTLTDMGR
T411 sPRSYSSTLTDMGRS
T413 RSYSSTLTDMGRSAP
S418 TLTDMGRSAPRERRG
K441 AKAVYDFKAQTSKEL
T444 VYDFKAQTSKELSFK
T455 LSFKKGDTVYILRKI
Y457 FKKGDTVYILRKIDQ
Y482 VGIFPISYVEKLTPP
T487 ISYVEKLTPPEKAQP
Y573-p NTKGAEDyPDPPIPH
S581 PDPPIPHSYSSDRIH
S583 PPIPHSYSSDRIHSL
S584 PIPHSYSSDRIHSLS
T657 RRTKFFGTFPGNYVK
K664 TFPGNYVKRL_____
  ArgBP2 iso4  
- gap
- gap
S9 NTGRDSQSPDsAKGF
S12-p RDSQSPDsAKGFRSV
- gap
- gap
K14 SQSPDsAKGFRSVRP
Y50 AVSPMSYYQRPFSPS
S55 SYYQRPFSPSAYSLP
Y59 RPFSPSAYSLPASLN
S76 IVMQHGTSLDSTDTY
T82 TSLDSTDTYPQHAQS
P84 LDSTDTYPQHAQSLD
S89 TYPQHAQSLDGTTSS
Y118 TVIKAPHYPGIGPVD
Y164 PDDDTDMYNTPYTYN
T166 DDTDMYNTPYTYNAG
Y175 YTYNAGLYNPPYSAQ
Y192 PAAKTQTYRPLSKSH
S196 TQTYRPLSKSHSDNS
S198 TYRPLSKSHSDNSPN
S200 RPLSKSHSDNSPNAF
S203 SKSHSDNSPNAFKDA
S212 NAFKDASSPVPPPHV
S233 LRPRDRSSTEKHDWD
T234 RPRDRSSTEKHDWDP
S253 VDTRKFRSEPRSIFE
S257 KFRSEPRSIFEYEPG
S294 EPGRKPLSSSRLGEV
S296 GRKPLSSSRLGEVTG
- gap
- gap
S304-p RLGEVTGsPsPPPRS
S306-p GEVTGsPsPPPRSGA
R319 GAPTPSSRAPALsPT
S324-p SSRAPALsPTRPPKK
Y335 PPKKPLDYVQDHsSG
S340-p LDYVQDHsSGVFNEA
F344 QDHsSGVFNEAsLyQ
S348-p SGVFNEAsLyQSSID
Y350-p VFNEAsLyQSSIDRS
S353 EAsLyQSSIDRSLER
S357 yQSSIDRSLERPMSs
M362 DRSLERPMSsASMAS
S363 RSLERPMSsASMASD
S364-p SLERPMSsASMASDF
S366 ERPMSsASMASDFRK
S377-p DFRKRRKsEPAVGPP
S391 PRGLGDQSASRTSPG
T395 GDQSASRTSPGRVDL
S396 DQSASRTSPGRVDLP
S405 GRVDLPGSSTTLTKS
K411 GSSTTLTKSFTSSSP
S415 TLTKSFTSSSPSsPs
S416 LTKSFTSSSPSsPsR
S417 TKSFTSSSPSsPsRA
S419 SFTSSSPSsPsRAKD
S420-p FTSSSPSsPsRAKDR
S422-p SSSPSsPsRAKDREs
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S429-p sRAKDREsPRSYSST
S432 KDREsPRSYSSTLTD
S432 KDREsPRSYSSTLTD
S434 REsPRSYSSTLTDMG
S435 EsPRSYSSTLTDMGR
T436 sPRSYSSTLTDMGRS
T438 RSYSSTLTDMGRSAP
S443 TLTDMGRSAPRERRG
K466 AKAVYDFKAQTSKEL
T469 VYDFKAQTSKELSFK
T480 LSFKKGDTVYILRKI
Y482 FKKGDTVYILRKIDQ
Y507 VGIFPISYVEKLTPP
T512 ISYVEKLTPPEKAQP
Y598 NTKGAEDYPDPPIPH
S606 PDPPIPHSYSSDRIH
S608 PPIPHSYSSDRIHSL
S609 PIPHSYSSDRIHSLS
T682 RRTKFFGTFPGNYVK
K689 TFPGNYVKRL_____
  ArgBP2 iso5  
- gap
- gap
S9 NTGRDSQSPDsAKGF
S12-p RDSQSPDsAKGFRSV
- gap
- gap
K14 SQSPDsAKGFRSVRP
Y50 AVSPMSYYQRPFSPS
S55 SYYQRPFSPSAYSLP
Y59 RPFSPSAYSLPASLN
S76 IVMQHGTSLDSTDTY
T82 TSLDSTDTYPQHAQS
P84 LDSTDTYPQHAQSLD
S89 TYPQHAQSLDGTTSS
Y118 TVIKAPHYPGIGPVD
Y164 PDDDTDMYNTPYTYN
T166 DDTDMYNTPYTYNAG
Y175 YTYNAGLYNPPYSAQ
Y192 PAAKTQTYRPLSKSH
S196 TQTYRPLSKSHSDNS
S198 TYRPLSKSHSDNSPN
S200 RPLSKSHSDNSPNAF
S203 SKSHSDNSPNAFKDA
S212 NAFKDASSPVPPPHV
S233 LRPRDRSSTEKHDWD
T234 RPRDRSSTEKHDWDP
S253 VDTRKFRSEPRSIFE
S257 KFRSEPRSIFEYEPG
S294 EPGRKPLSSSRLGEV
S296 GRKPLSSSRLGEVTG
- under review  
- under review  
S304-p RLGEVTGsPsPPPRS
S306-p GEVTGsPsPPPRSGA
R319 GAPTPSSRAPALSPT
S324 SSRAPALSPTRPPKK
Y335 PPKKPLDYVQDHSSG
S340 LDYVQDHSSGVFNEA
F344 QDHSSGVFNEASLYQ
S348 SGVFNEASLYQSSID
Y350 VFNEASLYQSSIDRS
S353 EASLYQSSIDRSLER
S357 YQSSIDRSLERPMSS
M362 DRSLERPMSSASMAS
S363 RSLERPMSSASMASD
S364 SLERPMSSASMASDF
S366 ERPMSSASMASDFRK
S377 DFRKRRKSEPAVGPP
S391 PRGLGDQSASRTSPG
T395 GDQSASRTSPGRVDL
S396 DQSASRTSPGRVDLP
S405 GRVDLPGSSTTLTKS
K411 GSSTTLTKSFTSSSP
S415 TLTKSFTSSSPSsPs
S416 LTKSFTSSSPSsPsR
S417 TKSFTSSSPSsPsRA
S419 SFTSSSPSsPsRAKD
S420-p FTSSSPSsPsRAKDR
S422-p SSSPSsPsRAKDREs
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S429-p sRAKDREsPRSYSST
S432 KDREsPRSYSSTLTD
S432 KDREsPRSYSSTLTD
S434 REsPRSYSSTLTDMG
S435 EsPRSYSSTLTDMGR
T436 sPRSYSSTLTDMGRS
T438 RSYSSTLTDMGRSAP
S443 TLTDMGRSAPRERRG
K466 AKAVYDFKAQTSKEL
T469 VYDFKAQTSKELSFK
T480 LSFKKGDTVYILRKI
Y482 FKKGDTVYILRKIDQ
Y507 VGIFPISYVEKLTPP
T512 ISYVEKLTPPEKAQP
Y598 NTKGAEDYPDPPIPH
S606 PDPPIPHSYSSDRIH
S608 PPIPHSYSSDRIHSL
S609 PIPHSYSSDRIHSLS
- gap
- gap
  ArgBP2 iso6  
- gap
- gap
- gap
- gap
- gap
S151-p LQQERQKsAVAAASQ
- gap
Y183 AVSPMSYYQRPFSPS
S188 SYYQRPFSPSAYSLP
Y192 RPFSPSAYSLPASLN
S209 IVMQHGTSLDSTDTY
T215 TSLDSTDTYPQHAQS
P217 LDSTDTYPQHAQSLD
S222 TYPQHAQSLDGTTSS
Y251 TVIKAPHYPGIGPVD
Y297 PDDDTDMYNTPYTYN
T299 DDTDMYNTPYTYNAG
Y308 YTYNAGLYNPPYSAQ
Y325 PAAKTQTYRPLSKSH
S329 TQTYRPLSKSHSDNS
S331 TYRPLSKSHSDNSPN
S333 RPLSKSHSDNSPNAF
S336 SKSHSDNSPNAFKDA
S345 NAFKDASSPVPPPHV
S366 LRPRDRSSTEKHDWD
T367 RPRDRSSTEKHDWDP
S386 VDTRKFRSEPRSIFE
S390 KFRSEPRSIFEYEPG
S427 EPGRKPLSSSRLGEV
S429 GRKPLSSSRLGEVTG
- gap
- gap
S437-p RLGEVTGsPsPPPRS
S439-p GEVTGsPsPPPRSGA
R452 GAPTPSSRAPALSPT
S457 SSRAPALSPTRPPKK
Y468 PPKKPLDYVQDHsSG
S473-p LDYVQDHsSGVFNEA
F477 QDHsSGVFNEAsLyQ
S481-p SGVFNEAsLyQSSID
Y483-p VFNEAsLyQSSIDRS
S486 EAsLyQSSIDRSLER
S490 yQSSIDRSLERPMSS
M495 DRSLERPMSSASMAS
S496 RSLERPMSSASMASD
S497 SLERPMSSASMASDF
S499 ERPMSSASMASDFRK
S510 DFRKRRKSEPAVGPP
S524 PRGLGDQSASRTSPG
T528 GDQSASRTSPGRVDL
S529 DQSASRTSPGRVDLP
S538 GRVDLPGSSTTLTKS
K544 GSSTTLTKSFTSSSP
S548 TLTKSFTSSSPSsPs
S549 LTKSFTSSSPSsPsR
S550 TKSFTSSSPSsPsRA
S552 SFTSSSPSsPsRAKD
S553-p FTSSSPSsPsRAKDR
S555-p SSSPSsPsRAKDREs
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S562-p sRAKDREsPRSYSST
S565 KDREsPRSYSSTLTD
S565 KDREsPRSYSSTLTD
S567 REsPRSYSSTLTDMG
S568 EsPRSYSSTLTDMGR
T569 sPRSYSSTLTDMGRS
T571 RSYSSTLTDMGRSAP
S576 TLTDMGRSAPRERRG
K599 AKAVYDFKAQTSKEL
T602 VYDFKAQTSKELSFK
T613 LSFKKGDTVYILRKI
Y615 FKKGDTVYILRKIDQ
Y640 VGIFPISYVEKLTPP
T645 ISYVEKLTPPEKAQP
Y731 NTKGAEDYPDPPIPH
S739 PDPPIPHSYSSDRIH
S741 PPIPHSYSSDRIHSL
S742 PIPHSYSSDRIHSLS
T815 RRTKFFGTFPGNYVK
K822 TFPGNYVKRL_____
  ArgBP2 iso7  
S13-p TSVKRVQssPNLLAA
S14-p SVKRVQssPNLLAAG
S26-p AAGRDSQsPDSAWRS
S29 RDSQsPDSAWRSYND
Y48-p TLNGDATySSLAAKG
- gap
K54 TySSLAAKGFRSVRP
Y90 AVSPMSYYQRPFSPS
S95 SYYQRPFSPSAYSLP
Y99 RPFSPSAYSLPASLN
S116 IVMQHGTSLDSTDTY
T122 TSLDSTDTYPQHAQS
P124 LDSTDTYPQHAQSLD
S129 TYPQHAQSLDGTTSS
Y158 TVIKAPHYPGIGPVD
Y204 PDDDTDMYNTPYTYN
T206 DDTDMYNTPYTYNAG
Y215 YTYNAGLYNPPYSAQ
Y232 PAAKTQTYRPLSKSH
S236 TQTYRPLSKSHSDNS
S238 TYRPLSKSHSDNSPN
S240 RPLSKSHSDNSPNAF
S243 SKSHSDNSPNAFKDA
S252 NAFKDASSPVPPPHV
S273 LRPRDRSSTEKHDWD
T274 RPRDRSSTEKHDWDP
S293 VDTRKFRSEPRSIFE
S297 KFRSEPRSIFEYEPG
S334 EPGRKPLSSSRLGEV
S336 GRKPLSSSRLGEVTG
- gap
- gap
S344-p RLGEVTGsPsPPPRS
S346-p GEVTGsPsPPPRSGA
R359 GAPTPSSRAPALsPT
S364-p SSRAPALsPTRPPKK
Y375 PPKKPLDYVQDHsSG
S380-p LDYVQDHsSGVFNEA
F384 QDHsSGVFNEAsLyQ
S388-p SGVFNEAsLyQSSID
Y390-p VFNEAsLyQSSIDRS
S393 EAsLyQSSIDRSLER
S397 yQSSIDRSLERPMSs
M402 DRSLERPMSsASMAS
S403 RSLERPMSsASMASD
S404-p SLERPMSsASMASDF
S406 ERPMSsASMASDFRK
S417 DFRKRRKSEPAVGPP
S431 PRGLGDQSASRTSPG
T435 GDQSASRTSPGRVDL
S436 DQSASRTSPGRVDLP
S445 GRVDLPGSSTTLTKS
K451 GSSTTLTKSFTSSSP
S455 TLTKSFTSSSPSsPs
S456 LTKSFTSSSPSsPsR
S457 TKSFTSSSPSsPsRA
S459 SFTSSSPSsPsRAKD
S460-p FTSSSPSsPsRAKDR
S462-p SSSPSsPsRAKDREs
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S469-p sRAKDREsPRSYSST
S472 KDREsPRSYSSTLTD
S472 KDREsPRSYSSTLTD
S474 REsPRSYSSTLTDMG
S475 EsPRSYSSTLTDMGR
T476 sPRSYSSTLTDMGRS
T478 RSYSSTLTDMGRSAP
S483 TLTDMGRSAPRERRG
K506 AKAVYDFKAQTSKEL
T509 VYDFKAQTSKELSFK
T520 LSFKKGDTVYILRKI
Y522 FKKGDTVYILRKIDQ
Y547 VGIFPISYVEKLTPP
T552 ISYVEKLTPPEKAQP
Y638 NTKGAEDYPDPPIPH
S646 PDPPIPHSYSSDRIH
S648 PPIPHSYSSDRIHSL
S649 PIPHSYSSDRIHSLS
T722 RRTKFFGTFPGNYVK
K729 TFPGNYVKRL_____
  rat

 
S27-p TSVKRVQsSPNLLAA
S28 SVKRVQsSPNLLAAG
S40 AAGRESHSPDSAWRS
S43 RESHSPDSAWRSYNG
Y62 TLNGDATYSSLAAKG
- gap
K68 TYSSLAAKGFRSVRP
Y104 AVSPVSYYQRPFSPS
S109 SYYQRPFSPSAYSLP
Y113 RPFSPSAYSLPASLN
S130 IIMPHGRSLDSAETY
T136 RSLDSAETYSQHAQS
S138 LDSAETYSQHAQSLD
S143 TYSQHAQSLDGTMGS
Y172-p TVIKAPHyPGIGPVD
Y218 PDEDTDMYNTPYTYN
T220 EDTDMYNTPYTYNAG
Y229 YTYNAGLYNSPYSAQ
Y246-p PAAKTQTyRPLSKSH
S250 TQTyRPLSKSHSDNG
S252 TyRPLSKSHSDNGTD
S254 RPLSKSHSDNGTDAF
G257 SKSHSDNGTDAFKEA
S266 DAFKEATSPVPPPHV
S282 PRPRDQSSTEKHDWD
T283 RPRDQSSTEKHDWDP
S302 VDTRKFRSEPRSIFE
S306 KFRSEPRSIFEYEPG
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S325 LQHERPVSVYQSSID
Y327 HERPVSVYQSSIDRS
S330 PVSVYQSSIDRSLER
S334 YQSSIDRSLERPSSS
S339 DRSLERPSSSASMAG
S340 RSLERPSSSASMAGD
S341 SLERPSSSASMAGDF
S343 ERPSSSASMAGDFRK
S354-p DFRKRRKsEPAVGPP
S368 PRGLGDHSSSRTSPG
T372 GDHSSSRTSPGRADL
S373 DHSSSRTSPGRADLP
S382 GRADLPGSSSTFTTS
T388 GSSSTFTTSFISsSP
S392 TFTTSFISsSPssPs
S393-p FTTSFISsSPssPsR
S394 TTSFISsSPssPsRA
S396-p SFISsSPssPsRAQG
S397-p FISsSPssPsRAQGG
S399-p SsSPssPsRAQGGDD
T466 NAEIWSSTEEAVSPK
S471 SSTEEAVSPKIKSRS
S478 SPKIKSRSCDDLLND
S489 LLNDDCGSFPDPKTK
S499 DPKTKSESMGSLLCD
S502 TKSESMGSLLCDEGS
S589 RGLLHGWSQSSTEEV
S591 LLHGWSQSSTEEVPR
S592 LHGWSQSSTEEVPRD
T593 HGWSQSSTEEVPRDV
S617 KLIQKSKSMPNLGDE
S627 NLGDEMLSPVTLEPP
S645 LCPKRRFSIESLLEE
S648 KRRFSIESLLEEETQ
K767-u TRFTTMLkHERAKHE
S796 SKLAFLVSPVPFRRK
T807 FRRKKVLTPQkQTEQ
K810-u KKVLTPQkQTEQAKC
K818 QTEQAKCKASVVEAL
S820 EQAKCKASVVEALDS
S844 KAEKRRGSLPDNSIL
K873-u NSSLNALkRSPMHQP
S907 GRMPHSASFPDVDTT
S933 LSLQDHESPRSYSST
S936 QDHESPRSYSSTLTD
S936 QDHESPRSYSSTLTD
S938 HESPRSYSSTLTDLG
S939 ESPRSYSSTLTDLGR
T940 SPRSYSSTLTDLGRS
T942 RSYSSTLTDLGRSVS
S947 TLTDLGRSVSRERRG
K971 AKAVYDFKAQTSKEL
T974 VYDFKAQTSKELSFK
T985 LSFKKGDTVYILRKI
Y987 FKKGDTVYILRKIDQ
Y1012 VGIFPISYVEKLTPP
T1017 ISYVEKLTPPEKAQP
Y1103 NTKGSEDYPDPPLPH
S1111 PDPPLPHSYsSDRIY
S1113-p PPLPHSYsSDRIYSL
S1114 PLPHSYsSDRIYSLS
T1187 RRTKFFGTFPGNYVK
K1194 TFPGNYVKRL_____
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