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Protein Page:
BMPR1B (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

BMPR1B a kinase of the STKR family. A type I cell-surface receptor for bone morphogenetic protein. Expressed at ighest level in the prostate. May be upregulated by androgen stimulation in cells which expresses the androgen receptor. Note: This description may include information from UniProtKB.
Protein type: EC; Protein kinase, Ser/Thr (receptor); Membrane protein, integral; EC; Protein kinase, TKL; Kinase, protein; TKL group; STKR family; Type1 subfamily
Cellular Component: integral to plasma membrane; plasma membrane; receptor complex
Molecular Function: protein serine/threonine kinase activity; protein binding; transforming growth factor beta receptor activity, type I; metal ion binding; SMAD binding; ATP binding; transmembrane receptor protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity
Biological Process: positive regulation of bone mineralization; protein amino acid phosphorylation; limb morphogenesis; BMP signaling pathway; positive regulation of osteoblast differentiation; ovulation cycle; dorsal/ventral pattern formation; eye development; retina development in camera-type eye; chondrocyte differentiation; ovarian cumulus expansion; inflammatory response; positive regulation of cell differentiation; skeletal development; retinal ganglion cell axon guidance; cartilage condensation
Reference #:  O00238 (UniProtKB)
Alt. Names/Synonyms: activin receptor-like kinase 6; ALK-6; ALK6; BMP type-1B receptor; BMPR-1B; BMPR1B; BMR1B; Bone morphogenetic protein receptor type-1B; bone morphogenetic protein receptor, type IB; CDw293; serine/threonine receptor kinase
Gene Symbols: BMPR1B
Molecular weight: 56,930 Da
Basal Isoelectric point: 7.78  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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Modification Sites and Domains Show Modification Legend
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Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend

Show Multiple Sequence Alignment


SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.



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