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Protein Page:
CKS1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
CKS1 Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. Belongs to the CKS family. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, regulatory subunit
Cellular Component: nucleoplasm
Molecular Function: protein binding; cyclin-dependent protein kinase regulator activity
Biological Process: cell proliferation; cell division; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G1/S transition of mitotic cell cycle
Reference #:  P61024 (UniProtKB)
Alt. Names/Synonyms: CDC2-associated protein CKS1; CDC28 protein kinase 1; CDC28 protein kinase 1B; CDC28 protein kinase regulatory subunit 1B; cell division control protein CKS1; CKS-1; CKS1; CKS1B; ckshs1; Cyclin-dependent kinases regulatory subunit 1; NB4 apoptosis/differentiation related protein; PNAS-143; PNAS-16; PNAS-18
Gene Symbols: CKS1B
Molecular weight: 9,660 Da
Basal Isoelectric point: 8.89  Predict pI for various phosphorylation states
Select Structure to View Below

CKS1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K4-ub ____MSHkQIyysDk
0 11 Y7-p _MSHkQIyysDkyDD
0 1 Y8-p MSHkQIyysDkyDDE
0 1 S9-p SHkQIyysDkyDDEE
0 1 K11-ub kQIyysDkyDDEEFE
0 7 Y12-p QIyysDkyDDEEFEy
0 1 Y19-p yDDEEFEyRHVMLPK
0 1 K26 yRHVMLPKDIAKLVP
0 26 S51-p RNLGVQQsQGWVHyM
0 2 Y57-p QsQGWVHyMIHEPEP
  mouse

 
K4 ____MSHKQIYYSDK
Y7 _MSHKQIYYSDKYDD
Y8 MSHKQIYYSDKYDDE
S9 SHKQIYYSDKYDDEE
K11 KQIYYSDKYDDEEFE
Y12 QIYYSDKYDDEEFEY
Y19 YDDEEFEYRHVMLPk
K26-ub YRHVMLPkDIAKLVP
S51-p RNLGVQQsQGWVHYM
Y57 QsQGWVHYMIHEPEP
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