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Protein Page:
TESK1 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
TESK1 a TKL kinase of the LISK fanily. Its testicular germ cell-specific expression and developmental pattern of expression in the mouse suggests that this kinase plays an important role at and after the meiotic phase of spermatogenesis. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; Kinase, protein; EC 2.7.12.1; TKL group; LISK family; TESK subfamily
Cellular Component: cytosol
Molecular Function: protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; metal ion binding; protein serine/threonine/tyrosine kinase activity; ATP binding
Biological Process: spermatogenesis
Reference #:  Q15569 (UniProtKB)
Alt. Names/Synonyms: Dual specificity testis-specific protein kinase 1; TESK1; Testicular protein kinase 1; testis-specific kinase 1
Gene Symbols: TESK1
Molecular weight: 67,684 Da
Basal Isoelectric point: 8.44  Predict pI for various phosphorylation states
CST Pathways:  Microtubule Dynamics
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

TESK1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
1 0 S220 EPLAVVGSPYWMAPE
0 1 R338 HNQGSVARGGPSATL
0 1 S342 SVARGGPSATLPRPD
0 2 S353 PRPDPRLSRSRsDLF
0 1 S357-p PRLSRSRsDLFLPPS
0 3 S364 sDLFLPPSPESPPNW
0 6 S437-p TPARRCRsLPSsPEL
0 5 S441-p RCRsLPSsPELPRRM
0 1 S553-p ALERTEPsPPPSAPR
  mouse

 
S215 EPLAVVGSPYWMAPE
R338-m1 YNQGSVPrGGPsATL
S342-p SVPrGGPsATLPRPD
S353-p PRPDPRLsRSRsDLF
S357-p PRLsRSRsDLFLPPs
S364-p sDLFLPPsPESPPSW
S439-p TPVRRCRsLPSsPEL
S443-p RCRsLPSsPELPRRM
S554 ALERTEPSPPPSAPR
  rat

 
S215-p EPLAVVGsPYWMAPE
R338 YNQGSVPRGGPSATL
S342 SVPRGGPSATLPRSD
S353 PRSDPRLSRSRSDLF
S357 PRLSRSRSDLFLPPs
S364-p SDLFLPPsPESPPSW
S439 TPVRRCRSLPSSPEL
S443 RCRSLPSSPELPRRM
S555 ALERTEPSPPPSAPR
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