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Protein Page:
UGT1A5 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
UGT1A5 UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family. 1 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Lipid Metabolism - androgen and estrogen; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.4.1.17; Xenobiotic Metabolism - drug metabolism - other enzymes; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - ascorbate and aldarate; Transferase; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Carbohydrate Metabolism - pentose and glucuronate interconversions
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: glucuronosyltransferase activity
Biological Process: metabolic process
Reference #:  P35504 (UniProtKB)
Alt. Names/Synonyms: GNT1; UD15; UDP glucuronosyltransferase 1 family, polypeptide A5; UDP glycosyltransferase 1 family, polypeptide A5; UDP-glucuronosyltransferase 1 family polypeptide A5s; UDP-glucuronosyltransferase 1-5; UDP-glucuronosyltransferase 1-E; UDP-glucuronosyltransferase 1A5; UDPGT; UDPGT 1-5; UGT-1E; UGT1; UGT1*5; UGT1-05; UGT1.5; UGT1A5; UGT1E
Gene Symbols: UGT1A5
Molecular weight: 60,071 Da
Basal Isoelectric point: 8.24  Predict pI for various phosphorylation states
Select Structure to View Below

UGT1A5

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K438-ac VINDKSYkENIMRLS
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