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Protein Page:
CAB39 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
CAB39 a adaptor protein that, together with STRAD-alpha, forms a regulatory complex capable of stimulating the activity of LKB1. Interacts with Mst4, which plays an essential role in brush border formation in intestinal epithelial cells. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Cellular Component: protein complex; cytosol
Molecular Function: protein serine/threonine kinase activity; protein serine/threonine kinase activator activity; protein binding; protein kinase activator activity; kinase binding
Biological Process: peptidyl-serine phosphorylation; protein heterooligomerization; insulin receptor signaling pathway; activation of protein kinase activity; peptidyl-threonine phosphorylation; cell cycle arrest
Reference #:  Q9Y376 (UniProtKB)
Alt. Names/Synonyms: CAB39; calcium binding protein 39; Calcium-binding protein 39; CGI-66; FLJ22682; MO25; Protein Mo25
Gene Symbols: CAB39
Molecular weight: 39,869 Da
Basal Isoelectric point: 6.43  Predict pI for various phosphorylation states
CST Pathways:  AMPK Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

CAB39

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K17 KSPADIVKNLKESMA
0 1 K45-ub KATEEVSkNLVAMKE
0 1 Y207-p AEFLEQHyDRFFSEY
0 1 K216 RFFSEYEKLLHSENY
0 1 T288 FVANPNKTQPILDIL
0 1 K297-ac PILDILLkNQAkLIE
0 1 K297 PILDILLKNQAkLIE
0 1 K301-ac ILLkNQAkLIEFLsk
0 2 K301-ub ILLkNQAkLIEFLsk
0 1 S307-p AkLIEFLskFQNDRT
0 1 K308-ac kLIEFLskFQNDRTE
0 2 T324 EQFNDEKTyLVKQIR
0 10 Y325-p QFNDEKTyLVKQIRD
  mouse

 
K17-ub KSPADIVkNLKESMA
K45 KATEEVSKNLVAMKE
Y207 AEFLEQHYDRFFSEY
K216-ub RFFSEYEkLLHSENY
T288-p FVANPNKtQPILDIL
K297 PILDILLKNQTKLIE
K297-ub PILDILLkNQTKLIE
K301 ILLkNQTKLIEFLSK
K301 ILLkNQTKLIEFLSK
S307 TKLIEFLSKFQNDRT
K308 KLIEFLSKFQNDRTE
T324-p EQFNDEKtyLVKQIR
Y325-p QFNDEKtyLVKQIRD
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