a adaptor protein that, together with STRAD-alpha, forms a regulatory complex capable of stimulating the activity of LKB1. Interacts with Mst4, which plays an essential role in brush border formation in intestinal epithelial cells. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: cytosol
Molecular Function: protein serine/threonine kinase activator activity; protein serine/threonine kinase activity; protein binding; protein kinase activator activity; kinase binding
Biological Process: protein heterooligomerization; activation of protein kinase activity; insulin receptor signaling pathway; cell cycle arrest; positive regulation of peptidyl-serine phosphorylation; protein amino acid phosphorylation
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.