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Protein Page:
PLA2G2E (human)

Overview
PLA2G2E PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids. Belongs to the phospholipase A2 family. Note: This description may include information from UniProtKB.
Protein type: Lipid Metabolism - linoleic acid; EC 3.1.1.4; Secreted, signal peptide; Secreted; Lipid Metabolism - arachidonic acid; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Phospholipase
Cellular Component: extracellular region
Molecular Function: phospholipase A2 activity; calcium ion binding
Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; inflammatory response; lipid catabolic process
Reference #:  Q9NZK7 (UniProtKB)
Alt. Names/Synonyms: GIIE sPLA2; Group IIE secretory phospholipase A2; PA2GE; Phosphatidylcholine 2-acylhydrolase 2E; phospholipase A2, group IIE; PLA2G2E; sPLA2-IIE
Gene Symbols: PLA2G2E
Molecular weight: 15,989 Da
Basal Isoelectric point: 8.61  Predict pI for various phosphorylation states
Select Structure to View Below

PLA2G2E

Protein Structure Not Found.


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Modification Sites and Domains  

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