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Protein Page:
ACER3 (human)

Overview
ACER3 Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity. Belongs to the alkaline ceramidase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, multi-pass; Lipid Metabolism - sphingolipid; Hydrolase; EC 3.5.1.-; Membrane protein, integral
Cellular Component: endoplasmic reticulum membrane; integral to Golgi membrane; integral to endoplasmic reticulum membrane
Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; positive regulation of cell proliferation; sphingosine biosynthetic process; ceramide metabolic process
Reference #:  Q9NUN7 (UniProtKB)
Alt. Names/Synonyms: ACER3; Alkaline CDase 3; Alkaline ceramidase 3; Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; AlkCDase 3; APHC; FLJ11238; PHCA; phytoceramidase, alkaline
Gene Symbols: ACER3
Molecular weight: 31,552 Da
Basal Isoelectric point: 8.87  Predict pI for various phosphorylation states
Select Structure to View Below

ACER3

Protein Structure Not Found.


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