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Protein Page:
GSTA4 (mouse)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
GSTA4 Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4- hydroxynonenal (4-HNE). Belongs to the GST superfamily. Alpha family. Note: This description may include information from UniProtKB.
Protein type: Other Amino Acids Metabolism - glutathione; EC 2.5.1.18; Transferase; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450
Cellular Component: mitochondrion; cytoplasm
Molecular Function: transferase activity; glutathione transferase activity; glutathione binding; drug binding
Biological Process: metabolic process
Reference #:  P24472 (UniProtKB)
Alt. Names/Synonyms: Glutathione S-transferase 5.7; Glutathione S-transferase A4; glutathione S-transferase, alpha 4; GST 5.7; GST A4-4; GST class-alpha member 4; GST5.7; Gsta; Gsta4; GSTA4-4; mGsta4
Gene Symbols: Gsta4
Molecular weight: 25,564 Da
Basal Isoelectric point: 6.77  Predict pI for various phosphorylation states
Select Structure to View Below

GSTA4

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       mouse

 
0 1 K6-sc __MAAKPkLYYFNGR
0 1 K84-ac AKYNLYGkDLKERVR
0 1 K84-sc AKYNLYGkDLKERVR
0 1 K117-ac PFKTPKEkEESYDLI
0 1 R127 SYDLILSRAKTRYFP
0 1 K138 RYFPVFEKILKDHGE
1 0 S189 QAFKTRISNIPTIkK
1 0 T193 TRISNIPTIkKFLQP
0 1 K195-sc ISNIPTIkKFLQPGS
  human

 
K6 __MAARPKLHYPNGR
K84 DKHNLFGKNLKERTL
K84 DKHNLFGKNLKERTL
Q117 PFLKPDDQQKEVVNM
K127-ub EVVNMAQkAIIRYFP
K138-ub RYFPVFEkILRGHGQ
S189-p QEYTVKLsNIPtIKR
T193-p VKLsNIPtIKRFLEP
K195 LsNIPtIKRFLEPGS
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