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Protein Page:
UGT1A10 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
UGT1A10 UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family. 1 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 2.4.1.17; Xenobiotic Metabolism - drug metabolism - other enzymes; Membrane protein, integral; Lipid Metabolism - androgen and estrogen; Carbohydrate Metabolism - ascorbate and aldarate; Cofactor and Vitamin Metabolism - retinol; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Carbohydrate Metabolism - pentose and glucuronate interconversions; Carbohydrate Metabolism - starch and sucrose; Xenobiotic Metabolism - metabolism by cytochrome P450
Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane
Molecular Function: protein homodimerization activity; enzyme binding; retinoic acid binding; protein kinase C binding; protein heterodimerization activity; glucuronosyltransferase activity
Biological Process: flavone metabolic process
Reference #:  Q9HAW8 (UniProtKB)
Alt. Names/Synonyms: GNT1; UD110; UDP glucuronosyltransferase 1 family, polypeptide A10; UDP glycosyltransferase 1 family, polypeptide A10; UDP-glucuronosyltransferase 1-10; UDP-glucuronosyltransferase 1-J; UDP-glucuronosyltransferase 1A10; UDPGT; UDPGT 1-10; UGT-1J; UGT1; UGT1*10; UGT1-10; UGT1.10; UGT1A10; UGT1J
Gene Symbols: UGT1A10
Molecular weight: 59,810 Da
Basal Isoelectric point: 6.88  Predict pI for various phosphorylation states
Select Structure to View Below

UGT1A10

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 Y334-p PQTVLWRyTGTRPSN
1 0 S432-p KAVINDKsYkENIMR
0 1 K434-ac VINDKsYkENIMRLS
  mouse

 
Y334 PQTVLWRYTGTRPSN
S432 KTVINNkSYkENIMR
K434 VINNkSYKENIMRLS
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