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Protein Page:
RhoE (human)

Overview
RhoE Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Binds ROCK1. Interacts with UBXD5. Ubiquitous. Belongs to the small GTPase superfamily. Rho family. Note: This description may include information from UniProtKB.
Protein type: G protein, monomeric, Rho; Motility/polarity/chemotaxis; G protein; G protein, monomeric
Cellular Component: Golgi membrane
Molecular Function: GTPase activity; protein binding; GTP binding
Biological Process: GTP catabolic process; small GTPase mediated signal transduction; actin cytoskeleton organization and biogenesis; cell adhesion
Reference #:  P61587 (UniProtKB)
Alt. Names/Synonyms: ARHE; memB; Protein MemB; ras homolog gene family, member E; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; RHO8; RHOE; RND3; small GTP binding protein Rho8
Gene Symbols: RND3
Molecular weight: 27,368 Da
Basal Isoelectric point: 8.78  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics  |  Microtubule Dynamics
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

RhoE

Protein Structure Not Found.


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Sites Implicated In
intracellular localization: S11‑p
protein stabilization: S11‑p

Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
1 2 S7-p _MKERRAsQKLsSKs
1 0 S11-p RRAsQKLsSKsIMDP
0 2 S14-p sQKLsSKsIMDPNQN
1 0 S210-p KNVKRNKsQRATKRI
1 1 S218-p QRATKRIsHMPsRPE
0 1 S222-p KRIsHMPsRPELsAV
0 1 S227-p MPsRPELsAVAtDLR
0 1 T231-p PELsAVAtDLRKDKA
1 0 S240-p LRKDKAKsCTVM___
  mouse

 
S7-p _MKERRAsQKLSSKS
S11 RRAsQKLSSKSIMDP
S14 sQKLSSKSIMDPNQN
S210 KNVKRNKSQRATKRI
S218 QRATKRISHMPSRPE
S222 KRISHMPSRPELSAV
S227 MPSRPELSAVATDLR
T231 PELSAVATDLRKDKA
S240 LRKDKAKSCTVM___
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