Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Binds ROCK1. Interacts with UBXD5. Ubiquitous. Belongs to the small GTPase superfamily. Rho family. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric, Rho; Motility/polarity/chemotaxis; G protein, monomeric
Chromosomal Location of Human Ortholog: 2q23.3
Cellular Component: Golgi membrane
Molecular Function: GTPase activity; protein binding; GTP binding
Biological Process: GTP catabolic process; small GTPase mediated signal transduction; actin cytoskeleton organization and biogenesis; cell adhesion
Alt. Names/Synonyms: ARHE; memB; Protein MemB; ras homolog gene family, member E; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; RHO8; RHOE; RND3; small GTP binding protein Rho8
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.