a Ca(2 )/calmodulin-dependent protein kinase of the PIM family. Highly expressed in hematopoietic tissues, in leukemic and lymphoma cell lines, testis, small intestine, colon and colorectal adenocarcinoma cells. Note: This description may include information from UniProtKB.
Protein type: EC 18.104.22.168; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; PIM family
Chromosomal Location of Human Ortholog: Xp11.23
Molecular Function: protein serine/threonine kinase activity; ATP binding
Biological Process: negative regulation of cell proliferation; cell proliferation; apoptotic mitochondrial changes; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein stabilization; positive regulation of transcription, DNA-dependent; response to virus; male meiosis; protein amino acid phosphorylation; positive regulation of autophagy; G1/S transition of mitotic cell cycle; negative regulation of apoptosis
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.