a protein kinase of the STE20 family. Interacts with androgen receptor (AR), and cotranslocates into the nucleus with AR in response to androgen. Highly expressed in testis and prostate tissues. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, STE; EC 188.8.131.52; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Nuclear receptor co-regulator; STE group; STE20 family; PAKB subfamily
Molecular Function: protein serine/threonine kinase activity; protein binding; Rac GTPase binding; ATP binding
Biological Process: regulation of apoptosis; cell migration; regulation of transcription, DNA-dependent; apoptosis; regulation of MAPKKK cascade; regulation of mitotic cell cycle; activation of protein kinase activity; stress-activated protein kinase signaling pathway; cytoskeleton organization and biogenesis; actin cytoskeleton organization and biogenesis; Rho protein signal transduction
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.