a protein kinase of the STE20 family. Interacts with androgen receptor (AR), and cotranslocates into the nucleus with AR in response to androgen. Highly expressed in testis and prostate tissues. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, STE; EC 220.127.116.11; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Nuclear receptor co-regulator; STE group; STE20 family; PAKB subfamily
Chromosomal Location of Human Ortholog: 15q14
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; ATP binding; receptor signaling protein serine/threonine kinase activity
Biological Process: regulation of transcription, DNA-dependent; apoptosis; cytoskeleton organization and biogenesis; mitotic cell cycle; protein amino acid phosphorylation
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.