a protein kinase of the STE20 family. Predominantly expressed in brain. Capable of promoting neurite outgrowth, and thus may play a role in neurite development. Associated with microtubule networks and induces microtubule stabilization. Its subcellular localization is tightly regulated during cell cycle progression. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, STE; EC 188.8.131.52; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; PAKB subfamily
Molecular Function: protein serine/threonine kinase activity; Rac GTPase binding; ATP binding
Biological Process: cell migration; apoptosis; regulation of mitotic cell cycle; locomotory behavior; cytoskeleton organization and biogenesis; learning; signal transduction; Rho protein signal transduction; memory; regulation of apoptosis; cell proliferation; regulation of MAPKKK cascade; stress-activated protein kinase signaling pathway; activation of protein kinase activity; cell growth; actin cytoskeleton organization and biogenesis
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.