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Protein Page:
SLC16A10 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
SLC16A10 Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 6q21-q22
Cellular Component: basolateral plasma membrane; integral to membrane; plasma membrane
Biological Process: amino acid transport; aromatic amino acid transport; ion transport; transmembrane transport
Reference #:  Q8TF71 (UniProtKB)
Alt. Names/Synonyms: Aromatic amino acid transporter 1; MCT 10; MCT10; Monocarboxylate transporter 10; MOT10; PRO0813; SLC16A10; solute carrier family 16 (monocarboxylic acid transporters), member 10; Solute carrier family 16 member 10; solute carrier family 16, member 10 (aromatic amino acid transporter); T-type amino acid transporter 1; TAT1
Gene Symbols: SLC16A10
Molecular weight: 55,493 Da
Basal Isoelectric point: 7.87  Predict pI for various phosphorylation states
Select Structure to View Below

SLC16A10

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S4-p ____MVLsQEEPDSA
0 1 S15-p PDSARGTsEAQPLGP
0 1 S211 GIVTAGSSVFTILLP
0 1 T214 TAGSSVFTILLPLLL
0 2 S263-p TSTKDKEsGGsGSsL
0 1 S266-p KDKEsGGsGSsLFsR
0 1 S268 KEsGGsGSsLFsRKK
0 7 S269-p EsGGsGSsLFsRKKF
0 1 S272-p GsGSsLFsRKKFSPP
0 1 T338-p VLMCIGVtsGVGRLL
0 1 S339-p LMCIGVtsGVGRLLF
0 1 S417 LVGAQDVSQAIGFLL
0 1 K491 TGKEKMEKMLENQNs
0 2 N497 EKMLENQNsLLsSSs
0 9 S498-p KMLENQNsLLsSSsG
0 8 S501-p ENQNsLLsSSsGMFk
0 6 S503 QNsLLsSSsGMFkKE
0 9 S504-p NsLLsSSsGMFkKES
0 2 K508-ub sSSsGMFkKESDSII
0 1 S511 sGMFkKESDSII___
  mouse

 
S4 ____MVPSQEEPAAE
N15 PAAERETNEAQPPGP
S208-p GIVTAGSsVFtILLP
T211-p TAGSsVFtILLPLLL
S260-p PSTKEKEsGGSRssF
S263 KEKEsGGSRssFFSR
S265-p KEsGGSRssFFSRRK
S266-p EsGGSRssFFSRRKL
S269 GSRssFFSRRKLSPP
T335 LFMCIGITSGVGRLL
S336 FMCIGITSGVGRLLF
S414-p LVGPQDAsQAIGFLL
K488-ub AGGEKMEkMLENQss
S494-p EkMLENQssLLsGss
S495-p kMLENQssLLsGssG
S498-p ENQssLLsGssGIFk
S500-p QssLLsGssGIFkKD
S501-p ssLLsGssGIFkKDs
K505-ub sGssGIFkKDsASII
S508-p sGIFkKDsASII___
  rat

 
S4 ____MVPSLEEPAAA
N16 AAAERETNEAQPPGP
S210 GIVTAGSSVFTILLP
T213 TAGSSVFTILLPLLL
S262-p PSSKEKEsEDSRssF
S265 KEKEsEDSRssFFSR
S267-p KEsEDSRssFFSRRK
S268-p EsEDSRssFFSRRKL
S271 DSRssFFSRRKLSPP
T337 LFMCIGVTSGVGRLL
S338 FMCIGVTSGVGRLLF
S416 LVGPQDASQAIGFLL
K490 TGGEKMEKMLANQSs
S496 EKMLANQSsLLSSSs
S497-p KMLANQSsLLSSSsG
S500 ANQSsLLSSSsGIFK
S502 QSsLLSSSsGIFKKE
S503-p SsLLSSSsGIFKKEs
K507 SSSsGIFKKEsDSII
S510-p sGIFKKEsDSII___
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