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Protein Page:
VAMP1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
VAMP1 Involved in the targeting and/or fusion of transport vesicles to their target membrane. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Cellular Component: mitochondrial outer membrane; neuron projection; synaptic vesicle membrane; integral to plasma membrane; cell junction
Molecular Function: protein binding
Biological Process: vesicle-mediated transport; synaptic transmission; neurotransmitter secretion
Reference #:  P23763 (UniProtKB)
Alt. Names/Synonyms: DKFZp686H12131; SYB1; synaptobrevin 1; Synaptobrevin-1; VAMP-1; VAMP1; Vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1)
Gene Symbols: VAMP1
Molecular weight: 12,902 Da
Basal Isoelectric point: 6.24  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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VAMP1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S2-p ______MsAPAQPPA
0 92 K54-ub IIRVNVDkVLERDQk
0 86 K61-ub kVLERDQkLsELDDR
0 15 S63-p LERDQkLsELDDRAD
0 1 S77 DALQAGASQFESSAA
0 1 S82 GASQFESSAAkLKRK
0 2 K85-ub QFESSAAkLKRKYWW
  mouse

► Hide Isoforms
 
S2 ______MSAPAQPPA
K54-ub IMRVNVDkVLERDQk
K61-ub kVLERDQkLsELDDR
S63-p LERDQkLsELDDRAD
S77-p DALQAGAsQFESsAA
S82-p GAsQFESsAAkLKRK
K85-ub QFESsAAkLKRKYWW
  VAMP1 iso2  
S2 ______MSAPAQPPA
K54 IMRVNVDKVLERDQK
K61 KVLERDQKLSELDDR
S63 LERDQKLSELDDRAD
S77 DALQAGASQFESSAA
S82 GASQFESSAAKLKRK
K85 QFESSAAKLKRKYWW
  rat

 
S2 ______MSAPAQPPA
K54 IMRVNVDKVLERDQK
K61 KVLERDQKLsELDDR
S63-p LERDQKLsELDDRAD
S77 DALQAGASVFESSAA
S82 GASVFESSAAKLKRK
K85 VFESSAAKLKRKYWW
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