It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line. Interacts with VIM and HINT1. Expressed in placenta, prostate and thymus. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Cellular Component: cytoplasm
Molecular Function: protein binding; zinc ion binding; p53 binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.