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Protein Page:
CDK3 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
CDK3 a protein kinase of the CDK family. May be involved in cell cycle control. Can phosphorylate histone H1. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CMGC; CMGC group; CDK family; CDK/CDK1 subfamily; CDK1 subfamily
Chromosomal Location of Human Ortholog: 17q25.1
Molecular Function: cyclin-dependent protein kinase activity; ATP binding
Biological Process: mitosis; cell proliferation; G0 to G1 transition; regulation of cell cycle; protein amino acid phosphorylation; G1/S transition of mitotic cell cycle
Reference #:  Q00526 (UniProtKB)
Alt. Names/Synonyms: CDK3; Cell division protein kinase 3; cyclin-dependent kinase 3
Gene Symbols: CDK3
Molecular weight: 35,046 Da
Basal Isoelectric point: 8.86  Predict pI for various phosphorylation states
Select Structure to View Below

CDK3

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
1 1496 T14-p VEKIGEGtyGVVyKA
2 3751 Y15-p EKIGEGtyGVVyKAK
0 1598 Y19-p EGtyGVVyKAKNRET
0 1 K33-ub TGQLVALkKIRLDLE
0 10 T158-p AFGVPLRtytHEVVT
0 10 Y159-p FGVPLRtytHEVVTL
0 102 T160-p GVPLRtytHEVVTLW
0 1 T198-p CIFAEMVtRKALFPG
0 1 S207-p KALFPGDsEIDQLFR
0 1 Y236-p GVTQLPDyKGSFPKW
0 1 S272-p QLLQYDPsQRITAKT
  mouse

 
T14-p VEKIGEGtyGVVyKA
Y15-p EKIGEGtyGVVyKAR
Y19-p EGtyGVVyKARNKVT
K33 TGQLVALKKIRLDLE
T158 AFGVPLRTYtHEVVT
Y159 FGVPLRTYtHEVVTL
T160-p GVPLRTYtHEVVTLW
T197 CIFAEMVTGKALFPG
S206 KALFPGDSEIDQLFR
Y235 GVSQMPDYQSSFPKW
S271 RLLQYDPSQRISAKT
  cow

 
T14 VEKIGEGTYGVVYKA
Y15 EKIGEGTYGVVYKAR
Y19 EGTYGVVYKARNKET
K33 TGQLVALKKIRLDLE
T158 AFGVPLRTYTHEVVT
Y159 FGVPLRTYTHEVVTL
T160 GVPLRTYTHEVVTLW
T198 CIFAEMVTRRALFPG
S207 RALFPGDSEIDQLFR
Y236 GVTQLPDYKGSFPKW
S272 QLLQYDPSRRISAKA
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