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Protein Page:
DDX29 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
DDX29 ATP-binding RNA helicase involved in translation initiation. Required for efficient initiation on mammalian mRNAs with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity. Belongs to the DEAD box helicase family. DEAH subfamily. Note: This description may include information from UniProtKB.
Protein type: Translation; EC 3.6.4.13; Helicase; EC 3.6.1.-
Chromosomal Location of Human Ortholog: 5q11.2
Cellular Component: mitochondrion
Molecular Function: translation initiation factor activity; ATP-dependent helicase activity; ribosomal small subunit binding; ATP binding
Biological Process: ATP catabolic process; translational initiation
Reference #:  Q7Z478 (UniProtKB)
Alt. Names/Synonyms: ATP-dependent RNA helicase DHX29; DDX29; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29; DEAH (Asp-Glu-Ala-His) box polypeptide 29; DEAH box protein 29; DHX29; FLJ21492; Nucleic acid helicase DDXx
Gene Symbols: DHX29
Molecular weight: 155,236 Da
Basal Isoelectric point: 8.3  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

DDX29

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 6 S27-p VSASRAKsAEAGIAG
0 1 S38-p GIAGEAQsKKPVSRP
0 11 Y67-p VKQGPKIysFNsTND
0 1 S68-p KQGPKIysFNsTNDS
0 7 S71-p PKIysFNsTNDSSGP
0 1 K87-ac NLDKSILkVVINNkL
0 1 K93-ac LkVVINNkLEQRIIG
0 1 S135-p YMALQAFsFKTKDIE
0 1 T138 LQAFsFKTKDIEDAM
0 1 S157-p LYGGDLHsALDWLCL
0 5 S192-p KSRPKFQsPQIQAtI
0 1 T198-p QsPQIQAtIsPPLQP
0 20 S200-p PQIQAtIsPPLQPKT
0 2 Y210-p LQPKTKTyEEDPKSK
0 1 T333-p RKKPPVAtEGESALN
0 1 S394-p VRKNLPKsPNPSFEK
0 1 K494-ub PRDLFIAkLLNKLkQ
0 1 K500-ub AkLLNKLkQQQQQQQ
0 1 S580-p PVFKHRDsIVETLKR
0 2 S637-p PRRISAVsLANRVCD
0 1 R668-m2 YQIRMESrACESTrL
0 1 R674-m1 SrACESTrLLYCTTG
0 1 S739-p LMSATVDsEKFSTYF
0 1 T795 LEEEEEVTINVTSKA
0 1 Y808-p KAGGIKKyQEyIPVQ
0 24 Y811-p GIKKyQEyIPVQTGA
0 1 T816 QEyIPVQTGAHADLN
0 1 H819 IPVQTGAHADLNPFY
0 1 T1159-p GGYRSEItyCRRNFL
0 1 Y1160-p GYRSEItyCRRNFLN
0 1 S1196 GFSSSTTSTSWEGNR
0 1 T1361-p DKILQIItELIKtEN
0 1 T1366-p IItELIKtENN____
  mouse

 
S27-p VSASRARsAEAGAVG
S38 GAVGEAQSKKPVARP
Y65 VKQGPKIYSFNsAND
S66 KQGPKIYSFNsANDS
S69-p PKIYSFNsANDSGGS
K85 NLDKSILKVVINNKL
K91 LKVVINNKLEQRIIG
S133 YMALQAFSFKtKDIE
T136-p LQAFSFKtKDIEDAM
S155 LHGGDLHSALDWLCL
S190 KSRPKFQSVQIQATL
T196 QSVQIQATLsPPQQT
S198-p VQIQATLsPPQQTKT
Q208 QQTKTKRQEEDPKIK
T331 KKKPAPATEAESALN
S392 VRKNLPKSPNPSFEK
K492 PRDLFIAKLLNKLKQ
K498 AKLLNKLKQQQQQQQ
S579-p PVFKHRDsIVETLKR
S636-p PRRISAVsLATRVCE
R667 YQIRMESRASESTRL
R673 SRASESTRLLYCTTG
S738 LMSATVDSDKFSTYF
T794-p LEEEEEItINVTSKA
Y807 KAGGVKKYQEYIPVQ
Y810 GVKKYQEYIPVQsGA
S815-p QEYIPVQsGAsPELN
S818-p IPVQsGAsPELNPFY
S1158 GGFRSEISYCQRNFL
Y1159 GFRSEISYCQRNFLN
S1192-p KAAGFSSsPSWEGRK
T1357 DKILQIITELIKTEN
T1362 IITELIKTENN____
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