Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
SSU72 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
SSU72 May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination. Belongs to the SSU72 phosphatase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Phosphatase; EC 3.1.3.16
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; CTD phosphatase activity
Biological Process: mRNA polyadenylation
Reference #:  Q9NP77 (UniProtKB)
Alt. Names/Synonyms: CTD phosphatase SSU72; FLJ13048; HSPC182; PNAS-120; RNA polymerase II subunit A C-terminal domain phosphatase SSU72; SSU72; Ssu72 RNA polymerase II CTD phosphatase homolog; SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
Gene Symbols: SSU72
Molecular weight: 22,574 Da
Basal Isoelectric point: 5.16  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

SSU72

Protein Structure Not Found.


STRING  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  Source  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
1 0 S3-p _____MPssPLRVAV
1 2 S4-p ____MPssPLRVAVV
1 0 S19-p CSSNQNRsMEAHNIL
0 3 K28-ub EAHNILSkRGFSVRS
0 1 T40-p VRSFGTGtHVkLPGP
0 2 K43-ub FGTGtHVkLPGPAPD
0 1 K51-ac LPGPAPDkPNVYDFk
0 6 K51-ub LPGPAPDkPNVYDFk
0 14 K58-ub kPNVYDFkTTYDQMY
0 2 K73-ub NDLLRKDkELYTQNG
  mouse

 
S3 _____MPSSPLRVAV
S4 ____MPSSPLRVAVV
S19 CSSNQNRSMEAHNIL
K28-ub EAHNILSkRGFSVRS
T40 VRSFGTGTHVkLPGP
K43-ub FGTGTHVkLPGPAPD
K51 LPGPAPDKPNVYDFK
K51 LPGPAPDKPNVYDFK
K58 KPNVYDFKTTYDQMY
K73-ub NDLLRKDkELYTQNG
  rat

 
S3 _____MPSSPLRVAV
S4 ____MPSSPLRVAVV
S19 CSSNQNRSMEAHNIL
K28 EAHNILSKRGFSVRS
T40 VRSFGTGTHVKLPGP
K43 FGTGTHVKLPGPAPD
K51 LPGPAPDKPNVYDFK
K51 LPGPAPDKPNVYDFK
K58 KPNVYDFKTTYDQMY
K73 NDLLRKDKELYTQNG
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.