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POU4F2 (human)

Overview POU4F2 Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Belongs to the POU transcription factor family. Class- 4 subfamily. Note: This description may include information from UniProtKB. Protein type: DNA binding protein Cellular Component: nuclear speck; nucleus Molecular Function: chromatin binding Biological Process: neuron differentiation; axon guidance; sensory perception of sound; estrogen receptor signaling pathway; retina development in camera-type eye; axon extension involved in development; MAPKKK cascade; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; neuromuscular process controlling balance; retinal ganglion cell axon guidance Reference #:  Q12837 (UniProtKB) Alt. Names/Synonyms: Brain-3B; Brain-specific homeobox/POU domain protein 3B; Brn-3B; BRN3.2; BRN3B; Brn3b POU domain transcription factor; PO4F2; POU class 4 homeobox 2; POU domain class 4 transcription factor 2; POU domain protein; POU domain, class 4, transcription factor 2; POU4F2 Gene Symbols: POU4F2 Molecular weight: 43,087 Da Basal Isoelectric point: 9.33  Predict pI for various phosphorylation states

Select Structure to View Below POU4F2

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	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		S43-p	SSAPIAPsAsSPSSS
0	1		S45-p	APIAPsAsSPSSSSN
0	1		S76-p	RSSSSSSsGSSGGGG
0	2		S84-p	GSSGGGGsEAMRRAC
0	1		K266-a	EAFAERFkQRRIkLG
0	1		K271-a	RFkQRRIkLGVTQAD
0	1		K345	ELFNGAEKKRKRTSI
0	1		K346	LFNGAEKKRKRTSIA

	mouse
S43	SSAPAAPSASSPSSS
S45	APAAPSASSPSSSSN
G78	SSSSSGSGGSGGGGG
S86	GSGGGGGSEAMRRAC
K268	EAFAERFKQRRIKLG
K273	RFKQRRIKLGVTQAD
K347-a	ELFNGAEkkRKRTSI
K348-a	LFNGAEkkRKRTSIA

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