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Protein Page:
PROTOR2 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
PROTOR2 May be part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization. Belongs to the PROTOR family. May replace PROTOR1 in the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Cellular Component: mitochondrion
Reference #:  Q6MZQ0 (UniProtKB)
Alt. Names/Synonyms: FLJ14213; FLJ22630; MGC16218; proline rich 5 like; Protein observed with Rictor-2; Protor-2; PROTOR2; PRR5L
Gene Symbols: PRR5L
Molecular weight: 40,836 Da
Basal Isoelectric point: 6.28  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

PROTOR2
Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 7 S28-p RPRPRFMsSPVLSDL
0 2 K86-u ENIRRLLkSELGSFI
0 1 K182-a LLLLAQSkLPSSIVQ
0 1 S231-p ISGDRSFsGPtYTLA
0 1 T234-p DRSFsGPtYTLARRH
  mouse

 
S28-p RPRPRFMsSPVLSEL
K86 ESIRRLLKSELGSFI
K182 VLLLAQSKLPSSVIQ
S231 ISGDRSCSGPTYSLA
T234 DRSCSGPTYSLARRH
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