Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
LDH-C (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
LDH-C Possible role in sperm motility. Belongs to the LDH/MDH superfamily. LDH family. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - cysteine and methionine; Oxidoreductase; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cancer Testis Antigen (CTA); Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - propanoate; EC 1.1.1.27
Cellular Component: cytoplasm; microtubule-based flagellum
Molecular Function: nucleotide binding; L-lactate dehydrogenase activity
Biological Process: sperm motility; glycolysis; ATP biosynthetic process; cellular carbohydrate metabolic process; lactate oxidation; lactate biosynthetic process from pyruvate
Reference #:  P07864 (UniProtKB)
Alt. Names/Synonyms: Cancer/testis antigen 32; CT32; L-lactate dehydrogenase C chain; lactate dehydrogenase C; LDH testis subunit; LDH-C; LDH-X; LDH3; LDHC; LDHX; MGC111073
Gene Symbols: LDHC
Molecular weight: 36,311 Da
Basal Isoelectric point: 7.08  Predict pI for various phosphorylation states
Select Structure to View Below

LDH-C
Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  Pfam  |  ENZYME  |  DISEASE  |  Source  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 1 E17 EKLIEDDENSQCKIT
0 1 K59-a DVALDKLkGEMMDLQ
0 2 S73 QHGSLFFSTSKITSG
0 1 K81 TSKITSGKDYSVSAN
0 1 T95-p NSRIVIVtAGARQQE
0 1 S128 IPAIVHYSPDCKILV
0 1 S137-p DCKILVVsNPVDILT
0 1 T220-p TLDPKLGtDsDKEHW
0 1 S222-p DPKLGtDsDKEHWKN
0 1 K224 KLGtDsDKEHWKNIH
0 1 K228 DsDKEHWKNIHKQVI
0 1 K232 EHWKNIHKQVIQSAY
0 1 K245-u AYEIIKLkGYTSWAI
0 1 S301-p VLGRNGVsDVVKINL
0 1 K317 SEEEALFKKSAEtLW
0 1 T322-p LFKKSAEtLWNIQKD
  mouse

 
K17-u QNLVPEDkLSRCKIT
R59 DADTNKLRGEALDLL
S73-p LHGSLFLsTPKIVFG
K81-u TPKIVFGkDYNVSAN
T95 NSKLVIITAGARMVS
S128-p VPGIVQNsPDCKIII
T137 DCKIIIVTNPVDILT
T220 SLNPAIGTDSDkEHW
S222 NPAIGTDSDkEHWkN
K224-u AIGTDSDkEHWkNVH
K228-u DSDkEHWkNVHkQVV
K232-u EHWkNVHkQVVEGGY
K245 GYEVLNMKGYTSWAI
T301 VLGQSGITDFVKVNM
K317-u AEEEGLLkKSADTLW
T322 LLkKSADTLWNMQKD
  rat

 
K17 QNLAPDEKQSRCKIT
K59 DADENKLKGEALDLL
S73 LHGSLFLSTPKIVFG
K81 TPKIVFGKDYSVSAN
T95 NSKLVIITAGARMVS
S128 VPGVIQNSPDCKIMI
T137 DCKIMIVTNPVDILT
S220 SLNPAIGSDSDKEQW
S222 NPAIGSDSDKEQWKT
K224 AIGSDSDKEQWKTVH
K228 DSDKEQWKTVHKQVV
K232 EQWKTVHKQVVDGGY
K245 GYEVLNLKGYTSWAI
- under review  
K317 TEEEALFKKSCDILW
I322 LFKKSCDILWNIQKD
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.