Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily. Note: This description may include information from UniProtKB.
Protein type: Transcription factor; Motility/polarity/chemotaxis
Molecular Function: ligand-dependent nuclear receptor binding; protein binding; enzyme binding; double-stranded DNA binding; transcription coactivator activity; transcription factor binding
Biological Process: transcription from RNA polymerase II promoter; response to drug; circadian rhythm; response to light stimulus; response to peptide hormone stimulus; response to cAMP; regulation of cell cycle; response to lipopolysaccharide; negative regulation of transcription from RNA polymerase II promoter; cellular response to hormone stimulus; osteoblast development; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; positive regulation of osteoblast differentiation; response to radiation; response to mechanical stimulus; response to cytokine stimulus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; aging
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.