Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily. Note: This description may include information from UniProtKB.
Protein type: Transcription factor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: protein complex; nucleolus; chromatin; nucleus
Molecular Function: ligand-dependent nuclear receptor binding; protein binding; enzyme binding; sequence-specific DNA binding; double-stranded DNA binding; transcription factor activity
Biological Process: circadian rhythm; transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; response to light stimulus; positive regulation of osteoblast differentiation; response to peptide hormone stimulus; response to mechanical stimulus; positive regulation of transcription from RNA polymerase II promoter; response to lipopolysaccharide; response to organic cyclic substance; osteoblast development; aging
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.