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Protein Page:
JunD (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
JunD Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily. Note: This description may include information from UniProtKB.
Protein type: Transcription factor; Motility/polarity/chemotaxis
Cellular Component: protein complex; nucleolus; chromatin; nucleus
Molecular Function: ligand-dependent nuclear receptor binding; protein binding; enzyme binding; sequence-specific DNA binding; double-stranded DNA binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; circadian rhythm; regulation of transcription from RNA polymerase II promoter; response to light stimulus; response to peptide hormone stimulus; positive regulation of osteoblast differentiation; response to mechanical stimulus; response to lipopolysaccharide; positive regulation of transcription from RNA polymerase II promoter; response to organic cyclic substance; osteoblast development; aging
Reference #:  P17535 (UniProtKB)
Alt. Names/Synonyms: activator protein 1; AP-1; jun D proto-oncogene; JUND; JunD-FL isoform; Transcription factor jun-D
Gene Symbols: JUND
Molecular weight: 35,174 Da
Basal Isoelectric point: 6.86  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

JunD

Protein Structure Not Found.


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Sites Implicated In
transcription, induced: S100‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S27-p GSGGSFAsPGRLFPG
0 1 T38-p LFPGAPPtAAAGsMM
0 2 S43-p PPtAAAGsMMKKDAL
0 1 T71-p PAAAPPPtPLRADGA
1 6 S90-p PPDGLLAsPDLGLLk
0 1 K97-ub sPDLGLLkLAsPELE
5 45 S100-p LGLLkLAsPELERLI
1 5 T117-p SNGLVTTtPTSSQFL
0 1 S131-p LYPKVAAsEEQEFAE
0 1 T245 ALKDEPQTVPDVPsF
0 3 S251-p QTVPDVPsFGEsPPL
1 29 S255-p DVPsFGEsPPLsPID
0 25 S259-p FGEsPPLsPIDMDTQ
0 2 T265 LsPIDMDTQERIKAE
0 1 S294-p KRKLERIsRLEEKVK
0 2 S305-p EKVKTLKsQNtELAs
0 1 T308-p KTLKsQNtELAstAs
0 2 S312-p sQNtELAstAsLLRE
0 1 T313-p QNtELAstAsLLREQ
0 1 S315-p tELAstAsLLREQVA
0 1 K325-ub REQVAQLkQKVLSHV
9164 : Phospho-c-Jun (Ser73) Antibody
  mouse

 
P35 PGGGGFAPPGRAFPG
T46 AFPGAPPTSSMLKKD
S48 PGAPPTSSMLKKDAL
S76 PGSATAPSALRPDGA
S90-p APDGLLAsPDLGLLK
K97 sPDLGLLKLAsPELE
S100-p LGLLKLAsPELERLI
T117-p SNGLVTTtPTSTQFL
S131 LYPKVAASEEQEFAE
T239-p ALKDEPQtVPDVPSF
S245 QtVPDVPSFGDsPPL
S249-p DVPSFGDsPPLsPID
S253-p FGDsPPLsPIDMDtQ
T259-p LsPIDMDtQERIKAE
S288 KRKLERISRLEEKVK
S299 EKVKTLKSQNTELAS
T302 KTLKSQNTELASTAS
S306 SQNTELASTASLLRE
T307 QNTELASTASLLREQ
S309 TELASTASLLREQVA
K319 REQVAQLKQKVLSHV
9164 : Phospho-c-Jun (Ser73) Antibody
  rat

 
P35 PGGGGFAPPGRAFPG
T46 AFPGAPPTSSMLKKD
S48 PGAPPTSSMLKKDAL
S76 PGSATAPSALRPDGA
S90 APDGLLASPDLGLLK
K97 SPDLGLLKLAsPELE
S100-p LGLLKLAsPELERLI
T117 SNGLVTTTPTSTQFL
S131 LYPKVAASEEQEFAE
T239 ALKDEPQTVPDVPSF
S245 QTVPDVPSFGDsPPL
S249-p DVPSFGDsPPLsPID
S253-p FGDsPPLsPIDMDTQ
T259 LsPIDMDTQERIKAE
S288 KRKLERISRLEEKVK
S299 EKVKTLKSQNTELAS
T302 KTLKSQNTELASTAS
S306 SQNTELASTASLLRE
T307 QNTELASTASLLREQ
S309 TELASTASLLREQVA
K319 REQVAQLKQKVLSHV
9164 : Phospho-c-Jun (Ser73) Antibody
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